Clinical Overview and Management Sore throat represents inflammation of any part of the respiratory mucosa of the throat, including the pharynx (pharyngitis) and tonsils (tonsillitis). The condition ranges from mild irritation to severe pain and is one of the most common presenting symptoms in community pharmacy settings.
Epidemiology In the UK, a general practitioner with 2000 patients typically sees approximately 120 people annually with throat infections. However, four to six times as many people visit pharmacies for self-treatment. Adults experience an average of two to three sore throats each year.
Etiology - Viral Infections Viral infections account for 70-90% of all sore throat cases. These cases are typically self-limiting and resolve within one week. Viral causes include: Rhinovirus Coronavirus Epstein-Barr virus (causing glandular fever)
Etiology - Bacterial Infections Bacterial infections comprise 10-20% of cases. The primary bacterial cause is Group A beta- haemolytic Streptococcus (Streptococcus pyogenes). These cases may require antibiotic treatment, though many resolve without intervention.
Pathophysiology - Inflammation Process The underlying mechanism involves Inflammation of the pharyngeal mucosa Local immune response activation Release of inflammatory mediators Development of mucosal edema Increased nerve sensitivity in the affected area
Pathophysiology - Clinical Manifestations The inflammatory process results in: Pain and discomfort Difficulty swallowing Local redness and swelling Possible exudate formation Cervical lymph node enlargement
Patient Assessment - Clinical Features Key features to evaluate: Severity and nature of throat pain Presence and degree of difficulty swallowing Fever occurrence and magnitude Cervical lymph node status Presence of tonsillar exudates Associated symptoms
Patient Assessment - Physical Examination Proper examination technique: Position patient at eye level Use adequate lighting (pen torch) Ask patient to say "ah" Examine tonsils for size, redness, and exudates Check posterior pharyngeal wall Assess cervical lymph nodes
Asking Questions - Age Considerations Age-related patterns: Streptococcal infection uncommon in children under 3 years Higher prevalence in school-age children (5-10 years) Common in young adults (15-25 years) Glandular fever most prevalent in adolescents
Asking Questions - Key Clinical Queries Essential questions for assessment: Duration of symptoms Presence of tender cervical glands Existence of tonsillar exudate History of fever Associated symptoms Previous treatments attempted
Asking Questions - Red Flags Critical symptoms requiring immediate referral: Duration exceeding 2 weeks Significant difficulty breathing Inability to swallow liquids Persistent high fever (>38.5°C) Voice changes Unilateral swelling
Treatment - General Approach Treatment principles: Most cases are self-limiting Focus on symptom relief Consider both local and systemic treatments Regular medication more effective than as-needed Patient education crucial
Treatment : Local Anesthetics Local anesthetic options: Lidocaine (various strengths) Benzocaine preparations Short duration of action Frequent dosing required Generally safe in pregnancy and breastfeeding
Treatment : Anti-inflammatory Agents Anti-inflammatory options: Benzydamine (rinse, spray, lozenge) Flurbiprofen lozenges Evidence supports effectiveness Different formulations for various age groups
Treatment - Systemic Analgesics Systemic pain relief: Paracetamol Ibuprofen Aspirin (adults only) Regular dosing more effective than as-needed Good evidence base for effectiveness
Contraindications - Local Anesthetics Contraindications for local anesthetics: Known hypersensitivity Children under specified age limits Open wounds or lesions Severe gag reflex History of adverse reactions
Contraindications - Anti-inflammatory Agents Contraindications for NSAIDs: Active peptic ulceration Severe renal impairment Third trimester pregnancy Known NSAID sensitivity History of gastrointestinal bleeding
Patient Counseling - Duration and Course Educate patients about: Expected duration (40% symptom-free after 3 days) Natural course of illness Normal progression of symptoms When to expect improvement Signs of complications
Patient Counseling - Self-Care Measures Advise patients on: Proper medication use and timing Adequate fluid intake Rest requirements Avoiding triggers Prevention strategies
Patient Counseling - Warning Signs Instruct patients to seek medical attention for: Symptoms persisting beyond 7 days Development of severe symptoms Appearance of red flags Lack of improvement with treatment New or worsening symptoms
Patient Counseling - Prevention Prevention strategies: Good hand hygiene Avoiding close contact when infectious Not sharing personal items Maintaining general health Avoiding known triggers