An invasion of pathogen or microorganism into the body that are capable to producing disease.
Stages of Infection
Incubation Stage
Time from the entrance of pathogen into the body to appearance of the first symptoms, during this time— Pathogen grow and multiply.
Prodome or Prodomal Stage
Time from onset of nonspecific symptoms such as fever, malaise, and fatigue to move specific symptoms .
Illness Stage
Time during which child demonstrates signs and symptoms specific to an infection type.
Convalescent Stage
Time when acute symptoms of illness disappear.
The presence of a pathogen does not mean that an infection will necessarily begin. The development of an infection happens in a cycle that depends on all elements in the chain of infections.
1. Infectious Agent
A microbial organism with the ability to cause disease. The greater the organism virulence (ability to grow and multiply), invasiveness (ability to enter tissue) and pathogenicity (ability to cause disease) the greater the possibility that the organism will cause an infection. Infectious agents are bacteria, virus, fungi, and parasites.
2. Reservoir
A place within which microorganism can thrive and reproduce. For example, microorganism thrive in human beings, animals, and inanimate objects such as water, table tops, and doorknobs.
3. Portal of Exit
A place of exit providing a way for a microorganism to leave the reservoir. For example, the microorganism leave the reservoir through the nose or mouth when someone sneezes or coughs Microorganism, carried away from the body by feces, may also leave the reservoir of an infected vowel
4. Mode of Transmission
Method of transfer by which the organism moves or is carried from one place to another. The hands of health care worker may carry bacteria from one person to another.
5. Portal of Entry
An opening allowing the microorganism to enter the host. Portals also result from tubes placed in body cavities, such as urinary catheters, or from punctures produced by invasive procedures such as intravenous fluid replacement.
6. Host
A person who cannot resist a microorganism invading the body, multiplying, and resulting in infection. The host is susceptible to the disease, lacking immunity or physical resistance to overcome the invasion by the pathogenic microorganism.