Stages of mitosis final project itp

Stages of mitosis. Slides to accompany wikispaces class site.

1. Stages of Mitosis Kimberly J. Luper B.S. M.S.

2. Objectives Distinguish the difference between mitosis and meiosis. List the functions of mitosis Define the mitotic phase. Discuss and explain the four stages of mitosis. Define cytokinesis.

3. Mitosis v/s Meiosis Mitosis is the duplication of the chromosomes in the nucleus and their separation into two identical sets in the process of somatic (“ of the body ”) cell division. Meiosis is restricted to one purpose, the production of eggs and sperm.

4. Functions of Mitosis Growth of all tissues and organs after birth. Replacement of cells that die. Repair of damaged tissues.

5. Mitotic Phase The mitotic phase of the cell cycle consists of: Nuclear division (mitosis) Cytoplasmic division (cytokinesis) to form two identical cells.

6. Four Stages of Mitosis

7. Prophase Prophase is actually divided into two steps: Early prophase Late prophase

8. Early Prophase Centrioles (two pairs) “Aster rays” Nuclear envelope containing c hromosomes.

9. Late Prophases Chromosome with t wo sisters chromatids Centromere Centrioles Spindle fibers /microtubules

10. Metaphase Metaphase plate Chromosome microtubules

11. Anaphase Daughter chromosomes

12. Telophase Cleavage furrow Nuclear membranes

13. Cytokinesis Daughter cells

14. Cytokinesis Cytoplasmic division : contractile ring from cleavage furrow around the center of the cell, dividing cytoplasm into separate and equal portions.

15. WHY? Why is the mitotic phase or mitosis phase so important?

16. WHY? Cell division or mitosis helps the body to replace dead cells and repair damaged tissue. (Paper cuts to major surgery)

17. Check In PMAT

18. PMAT P ro(before) phase : Chromatin fibers condense into paired chromatids; nucleus envelope disappears; each centrosome moves to an opposite pole of the cell. 2. M eta( after) phase : Centromeres of chromatid pairs line up at metaphase plate.

19. PMAT 3. A na(apart) phase : Centromeres split; identical sets of chromosomes move to opposite poles of the cell. 4. T elo (end) phase : Nuclear envelopes and nucleoli reappear; chromosomes resume chromatin form; mitotic spindles disappear.

20. References Tortora , G.J. & Derrickson , B. (2012). Principles of Anatomy and Physiology (13th ed.). Hoboken, NJ: John Wiley & Sons. Martini, F.H., Nath , J.L. (2012) Fundamentals of Anatomy & Physiology (9th ed.). San Francisco, C.A. Pearson Education, Inc.