Strontium doped beta tricalcium phosphate.pptx

Orthopedic applications

1. DEPRTMENT OF PHYSICS UNIVERSITY OF NARPWAL Synthesis and Characterization of Strontium-doped Beta Tricalcium Phosphate for Potential Orthopedic Applications MUHAMMAD UMAR 21-UON-1069 SUPERVISOR: DR. USMAN TARIQ

2. OUTLINE INTRODUCTION SIGNIFICANCE SCOPE OBJECTIVE RESEARCH METHODOLOGY RESULTS AND DISCUSSION CONCLUSION BONE GRAFTING

3. Pure and Sr- β TCP is a calcium phosphate ceramic that closely resembles the mineral component of bone and teeth. It is widely used in biomedical applications due to its biocompatibility, osteoconductivity, and bioactivity. INTRODUCTION

4. Bone grafting Autograft Self Allograft Different individual, same specie xenograft Different individual, different specie

5. OBJECTIVEs To synthesize pure and Strontium doped β TCP . To characterize of pure and strontium doped β TCP .

6. SIGNIFICANCE Pure beta-tricalcium phosphate (β-TCP) is a biocompatible ceramic material used in bone grafting.  Doping β-TCP with strontium (Sr) enhances its properties, making it a more promising biomaterial for bone regeneration.

7. SCOPE Pure and strontium doped beta tricalcium phosphate prepared using wet chemical precipitation method. Calcination of pure and strontium doped beta tricalcium phosphate was about at temperature 900 C FOR 2h. characterize using XRD and FTIR

8. Research Methodology Filtration Solution Preparation Mixing Aging of prepared solution Drying Calcination Gridding

9. Solution Preparation of β TCP In a typical reaction, calcium nitrate (Ca(NO3)24H2O) was dissolved in (100 mL) double-distilled water .

10. MIXING Diammonium hydrogen phosphate ((NH4)2HPO4) was added drop wise under constant stirring to the solution of calcium nitrate, pH of the solution was adjusted 7 to 9 by using ammonium hydroxide .

11. Nominal composition of Sr -βTCP samples   Reactants (mole) Samples Ca 2+ PO 4 3- Sr 2+ Βtcp 8.88 6.00 0.00 1Sr- βTCP 8.63 6.00 0.25 2Sr- βTCP 8.38 6.00 0.5 3Sr- βTCP 8.13 6.00 0.75 4Sr- βTCP 7.88 6.00 1.00

12. Aging The mixture was refluxed and aging about 24h.

13. Filtration The resulting suspension was filtered, washed with doubly distilled water.

14. Drying Dry at 100C for 3 h.

15. Calcination Calcinate at 900 C for 4 h to produce β -TCP.

16. Grinding Make a sample in powder from by gridding the calcinied β TCP. Note Sr-βTCP series was prepared by using the same method except that the corresponding amount of strontium nitrate was added in the solution of Ca(NO3)24H2O

17. Results and Discussion

18. XRD Spectrum of pure β -TCP

19. FTIR Spectrum of Pure- β TCP FTIR Spectrum of pure β -TCP

20. XRD Spectrum of Sr- β TCP .

21. FTIR Spectrum of Sr- β TCP FTIR Spectrum of pure β -TCP sr - β tcp .

22. CONCLUSION Pure and Strontium doped β TCP has been successfully synthesized using chemical precipitation method. XRD results showed decrease in the degree of crystallinity with increasing Strontium content. The synthesized samples can be useful for injectable cement preparation for potential orthopedic applications .