Sudama Meher ATVA P.P. final draft 2.pptx

Phosphorus poisoning

1. Phosphorus Poisoning Govt. Ayurvedic College & Hospital , Balangir Dept. Of Agad Tantra Presented by ; Sudama Meher Roll No : 31 2nd Prof. BAMS Guided by Dr. Lincon Sethi ( HOD ) Dr. Subrat Kumar Bhutiya Dr. Lily Meher

2. CONTENT 1. Introduction 2. It’s uses 3. Poisoning & it’s types 4. Diagnosis 5. Treatment 6. PM findings 7. Medico Legal Aspects

3. Introduction Phosphorus, an essential mineral, is naturally present in many foods and available as a dietary supplement. Phosphorus is a component of bones, teeth, DNA, and RNA. It has symbol P and atomic number 15. Elemental phosphorus exists in two major forms, white phosphorus and red phosphorus.

4. Pictures of different types of phosphorus available.

5. Use Matches Fireworks Military Uses like bombs , bullets etc Insecticides & Rodenticide ( Zinc Phosphide ) Fertilizer Medicine ( Homeopathy )

6. Poisoning Fatal dose - 60mg -120mg Mode of action – protoplasmic poison, hepatotoxin Cause shock, CVS collapse; skin, mucosa irritant. Poisoning types : 1. Fulminant 2. Acute 3. Chronic

7. Fulminant poisoning Ingestion of massive doses - <2g Peripheral vessel collapse Death in 12 to 24 hours

8. Acute poisoning Common type Stages I II & II Stage I up to 3 days Local side effects – burning pain, vomiting, diarrhoea, pain abdomen. Stage II Up to several days after stage- I Symptom-free. Patient well enough to be discharged

9. Stage III Due to systemic effects after absorption Gl symptoms reappear, more severe Prominent liver damage manifestations – hepatomegaly, jaundice, pruritus, bleeding, hepatic encephalopathy – drowsiness, confusion, ataxia, flapping tremor, stupor, coma.

10. Chronic poisoning Long term occupational exposure to phosphorus pentoxide fumes Phossy jaw, Glass jaw, Lucifer’s jaw. Toothache recurrence extraction – bone exposed – necrosis, osteomyelitis of lower jaw.

11. Diagnosis Garlicky odour of breath & vomit. Fuming, luminous vomitus & stools. Evidence of hepatic, renal failure Haemorrhages of skin & mucous membranes Hypokalaemia, hyperchloraemia , hypocalcaemia, hyperphosphataemia , hypophosphataemia

12. TREATMENT Gastric Lavage with KMnO4 (1:5000) IV Fluids (Glucose , Calcium Gluconate) to treat shock, hypoglycaemia, hypocalcaemia etc Use of steroids ( dexamethasone like corticosteroid to treat shock) Anti convulsants for Seizures. ( Clonapazam ) Use analgesics for pain relief . ( Aceclofenac , Diclofenac etc )

13. PM FINDINGS EXTERNAL Phossy jaw Purple rashes Garlic like smell Mucous membrane of mouth is corroded. INTERNAL Multiple haemorrhages in muscle , serosa , mucosa , liver , lungs , brain. Liver is swollen , yellow and soft. Stomach and intestine’s mucous membrane are corroded in patches

14. Medico-Legal Aspects Accidental ; by children , or by contaminated food Suicidal ; Rat killing paste are often used Homicidal ; Formerly used. Now rare. Abortifacient ; Oral , Vaginal

15. Thank you… @ sudamameher _