Technology transfer

Technology transfer

1. Technology Transfer 1 PRESENTD BY :- PATIL PRANJAY SADASHIV. FIRST YEAR M.PHARM. DEPARTMENT OF QUALITY ASSURANCE. H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur

2. Introduction 1-4 Technology transfer is the practice of transferring scientific findings from one organization to another for further development. Which is mainly concerned with the transfer of technology from the research areas to the “Production and Quality Assurance” environment. The process by which existing knowledge , facilities or capabilities developed under R & D are utilized to fulfill public and private need. 2

3. It is the process by which a developer of technology makes its technology available to commercial partner that will exploit technology. Technology transfer is the intersection between business, science, engineering, law and government. 3

4. Reasons for Technology Transfer 4 Lack of manufacturing capacity. Lack of resources to launch product commercially. Lack of marketing and distribution capability. Form technology alliance to exploit each other’s strength. 4

5. Technology Transfer Agents R&D Units • Universities. • Public Research Centers. • Technology Institutes ( institutions, labs etc ). Companies • Supplier of technology and R&D to third parties. • Large R&D department • Suppliers… 5

6. IDEA Research Development Production Manufacturing Distribution Start-up Firms R & D Firms Larger Companies Universities Research Institutes MARKET 6

7. TYPES OF TECHNOLOGY 5 1)EMERGING TECHNOLOGY- It is a technology that currently is undergoing batch scale testing. 2)INNOVATIVE TECHNOLOGY - It is a technology that the under the scale up. 3)ESTABLISHED TECHNOLOGY- It is a technology which already established in market. 7

8. CONTENT OF TECHNOLOGY TRANSFER 5-6 6 P 8

9. Proper Research – By proper research we mean firstly that in which the result are reproducible and issues such as scale up. Proper work - This refer to work should be in proper way, so that proper guidance will available for further development. 9

10. Pricing – -Too high price can put off buyer, leaving the technology unsold. - There are basically two model regarding pricing Price charged for a technology should depend upon market force. Price charged should include all expenses involved in developing it. Publicity – It is important to identify and then approach buyer i.e. adopt targeted Publicity and not blanket publicity. 10

11. Partnership – This means working along with industry. Industry takes it up, manufacturer and makes available to society. Partnership are important to ensure your technology is successfully adopted. People’s Acceptance – It is no use trying to develop a technology which people will not accept. 11

12. Steps involved in T echnology Transfer 3 1. Development of technology by R & D: Design of procedure and selection of excipients by R & D Identification of specification and quality by R & D 2. Technology transfer from R & D to production: Master formula card. Master packaging card. Master formula. Specifications & standard test procedure. 12

13. 3. Optimization and Production: Validation studies Scale up for production 4. Technology transfer documentation: Development report. Technology transfer plan. Report. 5. Check & Approval: 13

14. FUNCTION OF TECHNOLOGY TRANSFER TEAM 5 Coordinate- Coordinating between technology users and developers, between researchers and manufactures is an important element of technology transfer. Nature- A main ingredient for moving technology from a research laboratory to a new business enterprise successfully is an environment that is supportive. Link- Cataloging resources related to business enterprises and connecting would be researchers and other technology developers to outside groups and organizations which can help in the process of starting new products, companies etc. 14

15. FACTOR AFFECTING TECHNOLOGY TRANSFER 5 Communication Factor Financial Factor External Factor Human Factor Corporate Factor Technology factor 15

16. Technology Transfer Checklist 2,6 1) Production master formula. 2) Manufacturing instruction. 3) Dispensing instruction. 4) Analytical methods. 5) Previous process validation. 6) Stability report. 7) Excipients specification & source. 8) Active specification & source. 16

17. 9) Primary packaging material specification & source. 10) Packaging instruction. 11) Customer complaints. 12) Process deviation file. 13) Analytical deviation file. 14) Reject/Rework file. 15) Specimen manufacturing batch record. 16) Specimen cartons , Labels. 17

18. Objectives of Technology Transfer To offer guidance & assistance to inventors & corporation. To provide a hands-on learning opportunity. To increase the general awareness. To accelerate scale-up and cost reduction. 18

19. EXAMPLE OF TECHNOLOGY TRANSFER 7 Chinese company offer technology for the production of L- Phenyl alanine by the enzyme method. Area of Application # Food industry Advantage- Advanced process. No environmental contamination. Clear production. 19

20. Stage of development Commercialized Economic data Total project cost 4 million Equipment 1.38million Target country world wide Language English 20

21. INSTITUTE IN INDIA ASSISTING IN TECHNOLOGY TRANSFER 8 Asia Pacific Centre for Transfer of Technology (APCTT) - APCTT is a regional institution of the United Nations Economic and Social Commission for Asia and the Pacific, servicing the Asia-Pacific region. - It was established in 1977 with the objective of facilitating technology transfer in the Asia-Pacific region. The Centre headquartered in New Delhi with host facilities provided by the Government of India. 21

22. Technology Bureau for Small Enterprises (TBSE). National Research & Development Corporation. Foundation for Innovation and Technology Transfer. 22

23. Conclusion In pharmaceutical industry, technology transfer means action to transfer of information and technologies necessary to realize quality of design of drugs during manufacturing. In pharmaceutical industry technology transfer refers to The journey from drug discovery to full scale commercialization. Effective technology transfer helps to provide process efficiency , control and maintain product quality 23

24. References Savant DA. The Pharmaceutical Sciences – Pharma Pathaway . Nirali Prakashan . 8 th ed. Chapter 46, Technology Transfer Guidence ; 2010, July: 2.325-2.349. Berry IR. Technology Transfer Consideration for Pharmaceuticals. Encyclopaedia of Pharmaceutical Technology. Wiley India Pvt. Ltd, New Delhi ; 3 rd ed. 2006: 20-30. Singh A, Aggarwal G. Technology Transfer in Pharmaceutical Industry: A Discussion. Int.J . of Pharma and Bio Sci ; 2010,Jul- Sub. 1(3):1-5. Feifei Y, Yingming Y. Research on Technology Transfer in the Pharmaceutical Industry. Ind.j . of Pharm. Sci. IPA; 2008, July- Aug; 70(4):11-14. 24

25. http://www.gdrc.org/uem/techtran.html http://bud.tic.ab.ca/venquest/yqt_home.html http://www.informaworld.com/smpp/title~content=t713172974 http://www.apctt.org/about_us/aboutus.html 25

26. THANKING YOU 26