Temper resistant packaging

Temper Resistant packaging slide containing multiple types of Packaging system

1. NAME-BIKRAM DUTTA
ROLL-20801914027
SETION-1 , GROUP –B
BHARAT TECHNOLOGY

2. CONTENTS –
Introduction
Materials to be used
Classification
Applications
Criteria

3. INTRODUCTION -
The requirement for temper resistant packaging is now one of the major considerations
in the development of packaging for pharmaceutical products .
Temper resistant package is one having an indicator to entry in which , if missing , can
reasonallybe expected to provide visible evidence to consumers that tempering has
occurred.
FDA approves the following configurations : film wrappers, blister package, strip
package, bubble pack, shrink seals , and bands oil , paper , plastic pouches , bottle seals
, tape seals , breakable caps , aerosol containers.

4. FLIM WRAPPER-
Film wrapping has been used extensively over the years for products
requiring package integrity or environmental protection.
It has categorizes into following types :
1.End folded wrapper.
2.Fin seal wrapper.
3.Shrink wrapper.

5. End folded wrapper-
The end folded wrapper is formed by passing the product into a sheet of over wrapping
film, which forms the film around the product and folds the edges in a gift wrap fashion.
The folded areas are sealed by pressing against a heated bar. The materials co
commonly used for this purpose are cellophane and polypropylene.

6. Fin seal wrapper-
The seals are formed by crimping the film together and sealing together the two inside
surfaces of the film seal.
Fin sealing is superior than end folded wrapper with good seal integrity the over wrap can
removed or opened by tearing the wrapper.
Shrink wrapper-
The wrap concept involves the packaging of the product in a thermoplastic film that has
been stretched and oriented during its manufacture.
An L shaped sealer seals the over wrap.
The major advantage of this type of wrapper are the flexibility and low cost of packaging
equipment.

7. FIN SEAL WRAPPER

8. Blister Package-
The blister package is formed by heat softening sheet of thermoplastic and
vaccumdrawing the softened sheet is released from the mould and proceeds to
the filling station of the packaging machine.
The semi rigid tray is previously formed is filling with tablets/capsules and lidded
with a heat sealable backing material .The backing material is usually heat seal
coated aluminiumfoil . The plastic material used includes PVC , polyethylene
combination . For added moisture protection polyvinyledenefluoride or poly
chlorotrifluoroethylenefilms may be laminated to PVC .
Advantages-
Unit dosage , convenience , child resistant , pleasing appearance , tamper resistant
.

9. BLISTER PACKAGE

10. Strip Packaging-
Strip package is a form of unit dose packaging that is commonly used
for the packaging of tablets and capsules . A strip package is formed by
feeding two webs of a heat sealable flexible film through a heated
crimping roller.
The product is dropped into the pocket formed prior to forming the
final set of seals . A number different packaging. For high barrier
applications a proper/polyethylene/foil/polyethylene laminations
commonly used.

11. STRIP PACKAGE

12. Bubble Pack-
The bubble pack can be made in several ways but is usually formed by
sandwiching the product between a thermoplastic film and a rigid
packing material similar to a sin blister.

13. Bottle Seals-
A bottle may be made temper resistant by bonding and inner seal to the rim of the bottle in such
a way that the product can only be attained by destroying the seal .
Typically glassine liners are two ply laminations use in two sheet of glassine paper bounded
together with wax or adhesive .
For pressure sensitive inner seals pressure sensitive adhesive is coated on the surface of the
inner seal as an encapsulated adhesive .
Tape Seals-
It involves the application of glued or pressure sensitive tape or label around or over the closure
of the package which is to be destroyed to obtain the product .
The paper used must often is a high density light weight paper with poor tear strength.

14. Shrink Banding-
The shrink band concept makes use of the heat shrinking characters of a
stretch oriented polymer usually PVC .
The heat shrinkable polymer-PVC is manufactured as a tube in a
diameter slightly larger then the cap and neck ring of the bottle to be
sealed .
This is the placed over the bottle cap and the package through a heated
tunnel , which shrinks the plastic cover around the cap , preventing the
disengagement of the cap without destroying the shrink band .

15. Breakable Caps-
Breakable closures come in many different designs .
The roll-on cap design of aluminiumshell used for carbonated beverages.
The bottom portion of the cap is rolled around the bottle neck finish.
The lower portion of the cap blank is usually perforated so that it breaks away
when the cap is unscrewed . The bottom portion of the closure has a tear away
strip.

16. Sealed Tubes-
Collapsible tubes used for packaging are constructed of metal , plastic or
lamination of foil , paper and plastic.
Metal tubes are still used for products that required high degree of barrier
protection .
Most of those are made of aluminum.
Extruded plastic tubes are widely used for products that are compactable and
limited protection of plastic .

17. Significance –
Extra strong and secure packaging .
Regulations for some pharmaceuticals require it .
Extra layers of packaging .
Packages can not be resealed .

18. Reference-
Lachman/Lieberman’s the theory and practice of industrial pharmacy ,
page no-1024-1030.

19. THANK YOU