Tertiary drug information resources “Literatures”

Drug information

1. Drug information Tertiary drug information resources “Literatures”

2. Classification of Tertiary Resources A. General References They are referral books. Their formats are either monographs or monographs plus chapters. Us e d th r o u gh the i r i n dex e s NOT t h r o u gh the i r conte n t lists. Tertiary resources

3. Classification of Tertiary Resources A. General References A monograph is a specialist work of writing (in contrast to reference works) on a single subject or an aspect of a subject, usually by a single author. Tertiary resources

4. A. General References 1- American Hospital Formulary Service (AHFS) Drug Information: This drug information resource is organized by monographs containing information on both Food and Drug Administration (FDA) approved and off-label uses of medications. Information about dosing in specific populations is also included, as is a wide variety of general information about medications. Tertiary resources

5. A. General References 1 - American Hospi t al Form u lary S erv i ce ( AHF S ) Drug Information: Some info r mation i s also ava i lable ab o ut co m pati b ility and stab ility of injectable formulations. Published annually with quarterly updates More clinically oriented. Available in paper text, internet resource, and a PDA version. Monographs listed alphabetically Infor mat i on i n mo n ograp h : C h e m is tr y , pharmaco l o g y , me chan i sm Dose, administration, pharmacokinetics Drug interactions, preparations, toxicity Tertiary resources

6. A. General References 2- British National Formulary: The standard reference for prescribing and dispensing drugs in Britain. Included a r e notes o n the di f fe r ent drug g r ou p s to help in the cho i ce of appropriate treatment. The BNF is updated in March and September of each year. Available on disk and CD-ROM as the Electronic British National Formulary and an electronic web-based format is also available. Tertiary resources

7. A. General References 3- Egyptian National Formulary: of f e rs the user valuable info r m at i on on a ll drugs i n c l uded i n the EDL regarding: uses, adverse effects, drug interactions, drugs used during pregnancy and lactation, pharmacogenetics, geriatric and paediatric drug use, importance of compliance with treatment regimens. Tertiary resources

8. A. General References 4- Clinical Pharmacology : ► Gold Standard, http://www.clinicalpharmacology.com/. ► T h is ele c t r onic database has monogra p hs o f p r escr i ption and nonprescription products as well as some dietary supplements. ► The database can also screen for drug interactions, create comparison tables for prescription drugs, determine intravenous (IV) compatibility, and search for tablets by description or imprint codes. ► There is a patient education section also. ► It is available via the Internet, CD-ROM, through an organization's Intranet, or for PDAs. Tertiary resources

9. A. General References 5- Drug Facts and Comparisons (F&C) htt p ://ww w .factsan d com p arisons . co m . 6- Drug Information Handbook MICROMEDEX®: Epocrates: http://www.epocrates.com 9-Physicians' Desk Reference (PDR): Tertiary resources

10. B. Specialized References 1- Therapy evaluation/drug of choice Pharma c ot h e r a p y Pathophysiolog i c App r o a ch (Dipi r o ) Focuses on drug therapy, good background information. Also covers non-drug treatment options. Updated edition about every 4 years. Applied Therapeutics: The Clinical Use of Drugs (Koda Kimble) Well-written with focus on drug therapy. • Updated every 4 years. Useful summary tables. • Case presentation format, may be more difficult to use as a quick reference. Tertiary resources

11. B. Specialized References 2- Adverse side effects of drugs Meyler's Side Effects of Drugs Chapters are organized by drug classification; adverse events are organized by drug name and then by organ system within each drug. Information is provided about adverse events and management. . Tertiary resources

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13. Alphabetical order by generic name. For m er l y k no w n as G uide l i nes for Adm i nis tra t i o n of Int ra v enous Medications to Pediatric Patients. Dose, concentration, rate, cautions. Only print edition. B. S p e c i a li z ed Ref e r e T n e c e r s tiary r esou r ces 3- Pediatric: Pediatric Injectable Drugs (“Teddybear Book”)

14. Tertiary resources B. Specialized References 3- PREGNANCY Drugs in Pregnancy and Lactation (Briggs) Excellent reference, gold standard. Updated every 4 years. Alphabetical by generic name. Generic name, class, & pregnancy risk factor. Summaries of risk to fetus and risk during breastfeeding. Referenced.

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16. Tertiary resources B. Specialized References DRUG INTERACTIONS Stockley's Drug Interactions 1. A typical monograph contains a summary, clinical evidence for the interactions under discussion, the probable mechanism, clinical importance and management. Covers interactions between therapeutic drugs, herbal medicines, foods, drinks, pesticides.

17. Tertiary resources B. Specialized References Compatibility and Stability Handbook on Injectable Drugs (Trissel’s) 1. Information on compatibility and stability with diluents and drugs 6- Drug Identification American Drug Index Cross-referenced by brand, generic, and chemical names IDENTIDEX® - Component of MICROMEDEX ® -Identify drug by imprint code.

18. Tertiary resources B. Specialized References Drugs.com Drug site Trust, http://www.drugs.com . This electronic resource has an easy to use imprint search. This is especially useful as it is available to patients and has no charge for use.