Thymus

Basic of thymus gland for B.Pharm student

1. ENDOCRINE SYSTEM (Thymus gland) Mr N.JEGAN Associate Professor K.M.COLLEGE OF PHARMACY. MADURAI.

2. Thymus gland-Location Location: It is located in the upper front of chest, directly behind your  sternum  and between your lungs.

3. Thymus gland-Structure Shape - Triangular in shape. Colour - Pinkish-gray  Weight - 10-15 gm at birth & grows until puberty. It has two lobes.

4. Thymus gland-Structure Each lobe is surrounded by a capsule It is divided into lobules which are separated from each by interlobular septum . Cortex is the outer portion. Medulla is the centre portion

5. Thymus gland- Internal Structure Cortex contains a large number of small densely packed precursors of T lymphocytes ( thymocytes ). Medulla consists of number of concentric bodies known as Hassall’s corpuscles .

6. Thymus gland- Hormone Secretion of thymus gland collectively called as Thymosin Derivatives of thymosin hormones 1.Thymulin 2.Thymosin α 1 3.Thymopoietin

7. Thymosin - Functions Development and maturation of T lymphocytes cell T Lymphocyte is the type of white blood cell that is an essential of the immune system in our body.

8. Thymosin - Functions

9. Development (Bone marrow) and maturation (Thymus gland) of T lymphocytes cell

10. Thymus gland- Disease Myasthenia gravis ( weakness and rapid fatigue of muscles  ) It  occurs when the thymus is abnormally large and produces antibodies that block or destroy the muscles' receptor sites.

11. Pure red cell aplasia R eduction of red blood cells (erythrocytes) produced by the bone marrow Hypogammaglobulinemia Not enough gamma globulins are produced in the blood .

12. THANKING YOU