Stiffed Spine Ankylosing Spondylitis (AS) is a chronic disorder which causes recurring inflammation of the bones in the head and trunk of the body. It is sometimes called Marie- Strümpell disease or Bechterew's syndrome. It most commonly affects the bones of the spine, but it can also affect the pelvis, ribs and even the eyes. Eventually, the disease can lead the vertebrae to fuse together completely, resulting in a condition known as "bamboo spine," in which the spinal column becomes completely rigid. AS usually begins in early adulthood. Men are more likely than women to be affected by the disease. Prevalence AS is most prevalent in Afro-Caribbean populations and Northern European countries. The overall prevalence of the disease is less than 0.3% of the general population. AS is diagnosed twice as often in men as in women, but many doctors believe the number of women with the disease is underestimated because women tend to have milder symptoms. Typically, signs and symptoms of AS usually first appear between the ages of 15 and 25. Risk Factors Sex: Males are more likely to develop ankylosing spondylitis than females. Age: The onset of ankylosing spondylitis generally occurs late in adolescence or in early adulthood. Heredity: The majority of people who develop ankylosing spondylitis have a specific gene known as the HLA-B27 gene. However, there are also many people who have the HLA-B27 gene who never develop AS.
Reasons We still have a lot to learn about what causes ankylosing spondylitis, but we do know quite a lot about what effects it has on the body, and why it causes the vertebrae to become stiff and rigid. People who have the particular HLA-B27 gene have a significantly greater risk of developing AS. It is also possible that infectious agents may be involved in the development of the disease. Classification There are four different types of ankylosing spondylitis: Slowly progressive Slowly progressive with periods of exacerbations Quick progressive Septic