Types of immunoglobulins.pdf (1).pdf....

A PowerPoint presentation about types of immunoglobulins.

1. Types of Immunoglobulins

Presented by
Mamdouh Sameh & Basel Ahmed & Ahmed Haitham
Mansoura National University
Faculty of Medicine

2. What are Immunoglobulin
Antibodies are crucial proteins produced by your immune system that provide active
defense against harmful substances entering the body. They effectively bind to these
invaders, aiding their removal from your system. Each antibody consists of four
polypeptide chains: two heavy chains and two light chains, which form a Y-shaped
structure. The unique amino acid sequence at the tips of the "Y" gives each type of
antibody its distinct shape.

3. How are Immunoglobulins produced
Antibodies are produced by B cells, which are
specialized white blood cells.When an antigen
comes into contact with a B cell, it triggers the
B cell to divide and create clones. These
cloned B cells, known as plasma cells, release
millions of antibodies into the bloodstream and
lymphatic system.

4. What are the 5 types of Immunoglobulin

5. IgM ( Immunoglobulin M) :
Types of Immunoglobulin and their function
Located in the blood and lymphatic system, IgM antibodies
serve as the first line of defense against infections and play a
significant role in immune regulation.
IgD ( Immunoglobulin D) :
This antibody is located on the surface of B cells. Although its
precise function remains somewhat ambiguous, experts
suggest that IgD may facilitate B cell maturation and
activation.
I
II

6. Types of Immunoglobulins and their function
Present in saliva, tears, mucus, breast milk, and
intestinal fluid, IgA plays a crucial role in
safeguarding against pathogens that are
ingested or inhaled.
Is the most prevalent antibody, comprising
approximately 70% to 75% of all
immunoglobulins in the body. It is mainly
found in blood and tissue fluids and protects
against viral and bacterial infections.
III
IV
IgG ( Immunoglobulin G) :
IgA ( Immunoglobulin A) :

7. Types of Immunoglobulins and their function
Primarily found in the skin, lungs, and mucous membranes, IgE
antibodies trigger mast cells (a type of white blood cell) to release
histamine and other chemicals into the bloodstream. This response can
lead to allergic reactions.
V
IgE ( Immunoglobulin E) :

8. Presented by
Mamdouh Sameh & Basel Ahmed & Ahmed Haitham