I. Umbilical artery Doppler
Idea:
Umbilical Arterial Flow is normally of low
resistance.
In hypoxic states:
relative placental hypoxia:
reactive VC of umbilical artery:
higher resistance:
decrease in diastolic flow
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Interpretation:
•Resistance index: best ability to
predict abnormal outcomes (RCOG,2002
Evidence level II)
•Enddiastolic flow
•Systolic/diastolic ratio
•Pulsatility index
•Diastolic average ratio
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Doppler indices
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•Resistance Index:
In normal pregnancy:
{progressive increase in end-diastolic velocity
{growth& dilatation of the umbilical circulation}:
Resistance index falls.
In fetal growth restriction and/or
preeclampsia:
> 0.72 is outside the normal limits from 26 w.
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•End Diastolic flow
In fetal growth restriction and/or preeclampsia:
is reduced, then
absent (AED) or
reversed (RED) in severe cases
Absent or reversed:
Fetal distress is almost certain:
Immediate BPP or NST or
Delivery may be indicated.
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•S/D
Should be <3.
Small increases in S/D= 3-5:
chronic intrauterine disease manifest by IUGR.
Not strictly useful:
{1. low sensitivity.
2. Gestation age dependent}.
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Normal
Absent
Reversed
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RED
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RED
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Absent
Reversed
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Advantages:Advantages:
1.In low risk
No benefit on mother or baby
(The Cochrane Library, 2003)
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2. In high risk:
Reduction of
perinatal morbidity and mortality
number of antenatal admissions
inductions of labor
resources compared with CTG
(Grade A RCOG, 2002; The Cochrane Library, 2003)
Comparing FHR monitoring, FBP and umbilical artery Doppler:
only umbilical artery Doppler had value in predicting poor perinatal
outcomes in SGA
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•Frequency of monitoring in SGA
fetuses with normal Doppler:
Once/2w (RCOG, 2002 Evidence level II)
•A 4-week U/S measurement interval was shown to be superior to a 2-
week interval, in terms of reducing the false –positive rate (Owen et al,
2001).
•Once/2w (Fortnightly) scans should be undertaken where
1.linear growth velocity is not maintained or
2.AC is below the third centile (IV)
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II.Uterine artery Doppler
•limited use in predicting FGR and
perinatal death (Grade A, RCOG,2002).
•Abnormal uterine artery suggest:
maternal cause for the growth
restriction
•Normal uterine artery Doppler
suggest:
fetal cause
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UAD: Normal
UAD: notch,
decreased diastolic
flow
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Prediction of preeclampsia
(Uterine Doppler velocimetry)
•Persistence of a Diastolic
Notch in uterine artery
waveform after 24 w
•Systolic/diastolic ratio >2.6
•RI > 0.58 after 24 weeks.