Uso potencial de la luz pulsada como tratamiento de rosacea

uso de la luz pulsada en rosacea

1. POTENTIAL IMPACT OF OCULAR INTENSE PULSED LIGHT ON EYELASH MICROBIOME IN SEVERE MEIBOMIAN GLAND DYSFUNCTION: REPORT OF 2 CASES Goals: To investigate the effect of IPL therapy on the eyelash microbiome of MGD patients compared to healthy individuals.

2. Introduction Introduction Meibomian gland dysfunction (MGD) : It is a common eye disorder that causes irritation, inflammation and dry eyes. It has been linked to an altered microbiome in the eyes. Intense pulsed light (IPL) therapy : It has been adapted as a therapeutic option for treat and improve the symptoms of MGD, offering long-term relief. This study investigates its effect on eyelash microbiota. Methods Two Thai women in their forties were analyzed, one with severe MGD and the other without the disease. Samples were taken before and after 2 to 4 sessions. from IPL.

3. Results Individuals with severe MGD were found to have lower bacterial diversity in their eyelashes compared to healthy individuals. Following IPL treatment, bacterial diversity increased, and the composition of the microbiome more closely resembled that of healthy individuals. The presence of was detected Koribacteraceae p predominated in severe MGD before treatment, with a decrease after IPL, while Bifidobacterium It predominated in healthy individuals and in post-treatment patients, suggesting a possible positive relationship with symptom improvement.

4. Discussion Limitations Microbial alterations : Differences in the ocular microbiome may be related to MGD. IPL Mechanisms : Relief of blockages in the meibomian glands, elimination of mites Demodex , and an increase in species that inhibit bacterial growth. IPL treatment may help restore a healthier microbiome in MGD patients, although more research is needed to confirm its long-term impact. Two participants were included, which limits the generalization of the results. The sample analyzed was homogeneous (Thai women aged 40 years) No other microorganisms such as fungi or viruses were evaluated. The long-term impact of IPL was not explored.

5. Conclusions IPL therapy can induce a positive change in the eyelash microbiome in patients with severe MGD, approaching the profile of healthy individuals, promoting a healthier environment. Further studies with larger samples are required to confirm these findings and better understand the role of certain bacterial taxa in MGD.