Value of a chemiluminescent microparticle immunoassay (CMIA) in neurosyphilis diagnosis.

Value of a chemiluminescent microparticle immunoassay (CMIA) in neurosyphilis diagnosis.

1. Value of a chemiluminescent microparticle immunoassay (CMIA) in neurosyphilis diagnosis . Jesús Martínez-López , Mª José Zamora- López , Rubén Tato -Rodríguez, Mª Ángeles Pallarés -González, Sandra Cortizo -Vidal, Santiago Pérez- Cachafeiro , Matilde Trigo-Daporta , Marta García-Campello Test Sensitivity Specificity Positive Predictive Value Negative Predictive Value R Spearman CSF-TP-CMIA 100% [66,4-100] 94,6% [81,8-99,3] 81,8% [48,2-97,2] 100% [90,1-100] 0,89 CSF-TPHA 100 % [66,4-100] 97,3% [85,8-99,9] 90,0% [55,5-99,9] 100% [90,3-100] 0,86 CSF-WBC COUNT 55,6% [24,4-86,0] 73,0% [55,9-86,2] 33,3% [11,9-61,6] 87,1% [70,1-96,3] 0,25 CSF-PROTEIN LEVEL 55,6% [21,4-86] 48,7 % [31,9-65,6] 20,8% [7,2-42,1] 81,8% [59,7-94,7] 0,01 SERUM-TP-CMIA 100% [66,2-100] 10,8% [3,1-25,4] 21,4% [10,3-36,8] 100% [40,2-100] 0,52 SERUM-RPR TITER 100% [66,2-100] 83,8% [68,0-93,8] 60,0% [32,3-83,6] 100% [88,7-100] 0,69 Table 1. Results - 95% CI are shown in brackets