SEMINAR PRESENTATION NAME:- HITARTHSINH.D.SOLANKI ROLL NO.:- 50 SUBJECT:- TOPIC:- Vehicles used for pharmaceutical preparations
INTRODUCTION :- Vehicles for pharmaceutical preparation Ideal properties
Vehicles For Pharmaceutical Preparation Substance which are of little or no therapeutic value but which are added to the formulation in order to :- Help the production. Maintain physiologically stability. Improve patient acceptability. To improve the functioning of the dosage form as a DDS. Pharmceuticals aids necessities adjuvants or excipients
Ideal Properties Physiologically inert Physiologically stable Do not impart any undesired taste , colour, and odour. Non toxic , Non irritant , Non sensitizing Effective in low concentration Free from microorganism Not interfere with bioavailability of the drug Accepted by regulatory authorities
Medium in which ingredients of a formulation are dissolve suspended or dispersed. Pharmaceuticals vehicles can be classified as under- Vehicles can be of many types depending their use and route of administration. The vehicle can be of any type oily , aqueous , solid and semi solid type VEHICLES
Aqueous vehicles Water , Aromatic water , Alcohol , Glycerine , Propylene glycol. Oily Vehicles Vegetables oils , Minerals oils , Organic oils bases Or Emulsified bases. Vehicles in liquid dosage form
Oleaginous Cacao butter , Adeps neutralis Aqueous PEGs or Glycerinated , gelatine Solid and Semi Solid Sugar and gum Semi solid dosage form
Creams and Gels Oily bases White petroleum , lanolin, cholesterol Aqueous Hydro alcoholic , Alcoholic and Non aqueous