Water soluble vitamins-B complex vitamins(D. Pharmacy)

Introduction, Water soluble vitamins ,B complex vitamins, Thiamine, Riboflavin ,Niacin ,Pyridoxine ,Folic acid ,Pantothenic acid ,Cyanocobalamin
Ascorbic acid

1. Water soluble vitamins (B complex vitamins) By Shaikh SANIYA m. pharmacy

2. Content Water soluble vitamins B complex vitamins Thiamine Riboflavin Niacin Pyridoxine Folic acid Pantothenic acid Cyanocobalamin Ascorbic acid

3. Water soluble vitamins A  vitamin  that can dissolve in  water .  Water - soluble vitamins  are carried to the body's tissues but are not stored in the body. They are found in plant and animal foods or dietary supplements and must be taken in daily. Any excess of  water - soluble vitamins  is quickly excreted in urine and will rarely accumulate to toxic levels.

4. B complex vitamins B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. Vitamin B complex  helps prevent infections and helps support or promote: cell health. growth of red blood cells. These include thiamine ( vitamin  B1), riboflavin ( vitamin  B2), niacin ( vitamin  B3), pantothenic acid ( vitamin  B5), pyridoxine ( vitamin  B6), biotin, folic acid and the cobalamins ( vitamin  B12).

5. Thiamine (vitamin B 1 )

6. 1.Thiamine It is first water soluble vitamin. Thiamine  is vitamin B1.  Thiamine  is found in foods such as cereals, whole grains, meat, nuts, beans, and peas.  Thiamine  is important in the breakdown of carbohydrates from foods into products needed by the body.

7. Physical properties It is Colorless crystals or white crystalline powder It has characteristic odor. It is Soluble in water. Its aqueous solution is most stable at pH 2 and stability decreases with increase in pH . It is unstable at pH at 5 Stability and storage It is oxidized on exposure to air It is stored in tightly closed containers and light resistant containers

8. Uses It is used to treat beriberi in main and polyneuritis in birds It involved in the synthesis of acetylcholine.

9. 2.Riboflavin (vitamin B 2 ) Riboflavin, also known as vitamin B₂, is a vitamin found in food and used as a dietary supplement.  Riboflavin  is a vitamin that is needed for growth and overall good health. It helps the body break down carbohydrates, proteins and fats to produce energy, and it allows oxygen to be used by the body.

10. Stability and storage Dry riboflavin is not affected by diffused light but in solution it is decomposed by presence of alkali. It is stored in tightly closed containers and light resistant containers Uses It is used to treat ariboflavinosis

11. 3.Niacin Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B₃, an essential human nutrient. It is white crystalline powder. It is odorless It is acidic taste Soluble in boiling water.

12. Stability and storage Niacin is most stable vitamin and is not destroyed by heating in acid or alkaline solution. It is stored in tightly closed containers and light resistant containers USES It is used for prophylaxis and treatment of pellagra. It is used to treat acute exacerbation of pellagra. It is used to treat peripheral vascular disease.

13. 4.Pyridoxine Pyridoxine  is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body.  Pyridoxine  is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia  Properties It is white crystalline powder. It is odorless It has bitter taste Soluble in water

14. Uses It is used to treat Epilepsy Hydrochronic anemia Nausea during pregnancy To get relief from depression Megaloblastic anemia Peripheral neuritis Dosage form: pyridoxine tablets

15. Folic acid

16. 5. Folic acid Folate, also known as vitamin B₉ and folacin, is one of the B vitamins. Folic acid  is a type of B vitamin that is normally found in foods such as dried beans, peas, lentils, oranges, whole-wheat products, liver, asparagus, beets, broccoli, brussels sprouts, and spinach.   Folic acid  helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer.

17. Properties It is an orange yellow microcrystalline powder. Odorless and tasteless Insoluble in water Soluble in dilute alkali hydroxides and carbonate solution Stability and storage: It is affected by light and atmosphere It is stored in tightly closed containers and light resistant containers

18. Uses It is used In synthesis of DNA To treat megaloblastic anemia For normal production of RBC To treat deficiency syndrome To treat mental deterioration due to its deficiency.

19. 6.Panthothenic acid Pantothenic acid , also called vitamin B 5  is a water-soluble B vitamin and therefore an essential nutrient. Properties Pantothenic acid is optically active White powder Odorless and bitter taste It is slightly hygroscopic Water soluble

20. Stability and storage It is stable in air but is slightly hydroscopic . It is unstable to acid , bases and heat. It is stored in tight closed containers and light resistant containers Uses To release energy from carbohydrate For degradation and metabolism of fatty acids In synthesis of steroids and steroid hormones. In its deficiency symptoms like neurological disorders, headaches, fatigue, sleep disturbance, nausea and vomiting.

21. Cyanocobalamins

22. 7.Cyanocobalamin (vitaminB 12 ) Vitamin B₁₂, also known as cobalamin It is a water-soluble vitamin It contains cobalt to which cyano group is covalently. It is composed of two heterocyclic systems.

23. Sources Vitamin B12 is naturally found in  animal products , including fish, meat,  eggs ,  milk , and  milk  products.

24. Properties It occurs as dark red crystals or crystalline powder. It is Odorless Tasteless It is sparingly soluble in water but soluble in alcohol.

25. Stability and storage It is hygroscopic and is affected by light. It is stored in tightly closed containers and light resistant containers

26. Uses It is used to treat pernicious anemia and its neurological disorder. It is used to treat macrocyclic anemia. It is used to treat neuroblastoma in children. It is used to treat megaloblastic anemia. Dosage form: Cyanocobalamin injection

27. Vitamin H

28. 8.Biotin Biotin  is a water-soluble vitamin. It's also known as vitamin H. biotin   helps to convert certain nutrients into energy. It also plays an important role in the health of your hair, skin, and nails. A biotin deficiency can lead to brittle nails.  taking supplements that contain biotin could improve the strength of their nails. Biotin deficiencies are relatively rare, but they can cause skin, hair, and nail problems.

29. Sources organ meats, such as liver and kidney yeast egg yolks cheese legumes, such as soybeans and peanuts leafy greens cauliflower mushrooms nuts and nut butters

30. Uses

31. Ascorbic acid

32. Ascorbic acid Vitamin C  is a water-soluble  vitamin  that's found in many foods, particularly fruits and vegetables. It's well known for being a potent antioxidant

33. Sources

34. Properties It occurs as colorless crystals or white or pale yellow crystalline powder. Odorless Acidic taste Soluble in water and alcohol Stability and storage It darkens slowly when exposed to air. It is stored in tight closed containers and light resistant containers

35. Uses It is used to prevent and treat scurvy. It is used to maintaining healthy skin,  blood vessels , bones and cartilage. It promotes healing of wounds and fractures it is used as antioxidants

36. Dosage forms Tablets Injections Capsules

37. Thankyou !