What is Gene Therapy and its implications to society, health and environment

For everyone use purposes

1. GT What is Gene Therapy?

2. GT The practice of inserting genes into person’s genome to replace faulty genes.

3. What does Gene Therapy use? 3 A vector, typically a virus, to deliver a gene to the cell where it’s needed

4. Gene reading machinery uses the information in the gene to build RNA and protein molecules. Add a footer 4 What happens once a vector is inside?

5. Single gene mutation. Add a footer 5 Who tend to be good candidate for gene therapy?

6. Which genes to pursue, have DNA of the genes in the lab, which tissues the disorder affects, what role the protein encoded by the gene plays within the cell of the tissues. Add a footer 6 What do you need to know about the patient before conducting gene therapy?

7. Only dividing cells, Can not target cells that have stopped dividing, nonviral . Add a footer 7 What does a retrovirus vector infect?

8. 8,000 base pairs . Add a footer 8 What is the maximum length of RNA in retrovirus vector?

9. RNA Add a footer 9 How does a retrovirus vector carry its genetic material?

10. Herpes Simplex Virus (HSV), known as Herpes, is a common infection that can cause painful blisters of ulcers. It primarily spreads by skin-to-skin contact. Its is treatable but not curable. Add a footer 10 What does the HSV do?

11. Type 1 (HSV-1) mostly spreads by oral contact and causes infections in or around the mouth (oral herpes or cold herpes). It can also cause genital herpes. Most adults are infected with HSV-1 Add a footer 11 Types of HSV

12. Type 2 (HSV-2) spreads by sexual contact and causes genital herpes. Most people have no symptoms or only mild symptoms. The infection can cause blisters or ulcers that can recur over time. Medicines can reduce symptoms but cant cure the infection. Add a footer 12