SECONDARY WOUND HEALING Arjun kumawat M.Sc.Nsg 1 st yr
Objectives Discuss small information about wound healing Definitions wound healing Enlist the types of wound healing Explain the phases of wound healing Describe the complication and factors affecting wound healing.
Definition Wound healing is a complex and dynamic process of restoring cellular structures and tissue layers. Types : - 1.Primary healing 2. Secondary healing Wound
Secondary wound healing This method of healing follow destruction of large amount of tissue or when the edges of a wound cannot be brought into apposition, eg.pressure ulcer . The phases of secondary healing are the same as in primary healing and the time taken for healing depends on the effective removal of the cause and the size of the wound.
Phases The phases of wound healing are :- Inflammatory phase Proliferation phase Maturation phase
1.Inflammatory phase It is initiated immediately after injury and lasts 3-6 days. Two major processes occur during this phase: hemostasis and phagocytosis . The body has stopped any further blood loss by coagulating (clotting.) Once the blood loss has stopped, the body immediately sends fluids containing plasma proteins, blood cells and antibodies to the wound site causing swelling, pain, fever, and redness around the wound site.
Cont……. Neutrophils and macrophages are also dispatched to the injury site to clean, scavenge for bacteria and prepare the injury site for healing. The injured site will be swollen and painful because of the inflammation; most of the pain will subside when the inflammation reduces naturally.
2.Proliferation phase This stage overlaps with the ending of the Inflammatory Phase . Fibroblasts have begun to enter and collect in the wound by around day 3 after the injury; this marks the start of the transition from Inflammatory Phase to Proliferation Phase.
Cont…. Granulation tissue (it consists of new blood vessels, fibroblasts, inflammatory cells, endothelial cells and the components of a new extracellular matrix) will begin to be seen in the wound by the end of the first week, this tissue will continue to grow until the wound is healed. This tissue contains the new blood vessels and other components to fill in the damaged tissue .
Cont…. Granulation tissue is normally bright red, moist, soft to the touch, and has a bumpy appearance. This takes approximately 8 weeks for a standard open healing excision wound and 4 weeks for a closed wound.
3.Maturation phase( Remodeling ) This stage overlaps with the Proliferation Phase towards the end of healing. It is the process of remodeling of the collagen fibres laid down in the proliferation phase. Nerve endings are re-growing and tissue is rearranging itself.
Cont…. In short, there is a lot of activity still happening long after your wound has healed on the surface. You may continue to feel tugging and tension from deep inside the wound for quite a while as the new tissue stabilizes.
Complication and factors affecting wound healing
SUMARIZATION Wound healing is a complex and dynamic process of restoring cellular structures and tissue layers. The human adult wound healing process can be divided into 3 distinct phases: the inflammatory phase, the proliferative phase, and the remodeling phase.
Bibliography Barbara kozier , fundamentals of nursing, edition 7 th ,publisher pearson , page no 860-865. Roos and Wilson, anatomy and physiology, edition 11 th , pub Elsevier, page no 359-362. Gerard j.tortora & bryan H. derrickson , principles of anatomy and physiology, edition 12 th ,pub john wiley , page no 162-164. http://www.biology-online.org/dictionary/Dna. http://www.answers.com/topic/dna. http://en.wikipedia.org/wiki/Chromoso