Zosyn and pneumonia sara bobbitt

Zosyn and Pneumonia

1. Zosyn and Pneumonia

2. Pneumonia Three major categories Bacterial Viral Mycoplasma (atypical)

3. Pathophsiology Extrinsic causes Irritants Causative Direct pulmonary injury

4. Pathophysiology Intrinsic causes Loss of upper airway protective mechanism Stroke Esophageal cancer

5. Pathophysiology Inflammation of the lungs Neutrophil response to bacteria Neutrophils move to extracellular space Neutrophils destroy bacteria causing inflammation

6. Pathophysiology Continued bacterial reproduction results in Ineffective gas exchange Ineffective breathing pattern

7. Zoysn - Pneumonia Treatment Combination Drug Piperacillin Broad-spectrum B-lactam antibiotic Tazobactam Antibacterial penicillin derivative

8. Zosyn Binds to penicillin receptors Effective in the reproductive stage of the bacterial. Has a half life of 0.7 hrs to 1.2 hrs Excreted in urine and feces Piperacillin is also excreted in bile.

9. Patient Safety Five right of medication administration IV fluid compatibility Lactated ringers Drug to drug interactions Vancomycin Allergy to penicillin

10. Conclusion Zosyn is an effective combination drug in the treatment of Pneumonia Patients must be assessed for allergies to penicillin Zosyn reaches peak thirty-min after administration

11. References Bacterial Pneumonia. (2017, November 07). Retrieved December 01, 2017, from https://emedicine.medscape.com/article/300157-overview#a3 Comerford, K. C. (2018).  Nursing 2018 drug handbook (38th ed., Pg. 1225- 1228). Philadelphia: Wolters Kluwer. Piperacillin/tazobactam (Rx). (2016). Retrieved November 12, 2017, from https://reference.medscape.com/drug/zosyn-piperacillin- tazobactam-342485#0 What You Need to Know About Pneumonia. (2017). Retrieved December 01, 2017, from https://www.hopkinsmedicine.org/healthlibrary/conditions/respiratory_dis orders/pneumonia_85,P01321