1st_Transcription about central dogma. science lesson

Central Dogma: Transcription

1. WELCOME TO SCIENCE CLASS!

2. PROTEIN SYNTHESIS TRANSCRIPTION

3. LESSON OBJECTIVES Identify the types and functions of RNA that are responsible for the production of proteins Demonstrate the transcription process

4. SWIPE LEFT OR SWIPE RIGHT ACTIVITY 1

5. The DNA molecule is composed of three types of component molecule: phosphate group, the sugar ribose, and the bases adenine, thymine, cytosine, guanine (A, T, C, G). STATEMENT NO. 1

6. STATEMENT NO. 2 DNA is a double helix like a twisted staircase

7. STATEMENT NO. 3 RNA contains cytosine, adenine, guanine, and uracil

8. STATEMENT NO. 4 Primase is an enzyme that is responsible for unzipping the DNA to prepare for replication process.

9. STATEMENT NO. 5 DNA formed in replication process is semi-conservative

10. BE AWARE, RNA! ACTIVITY 2

11. The messenger RNA (mRNA) contains genetic information from the DNA (through a process of transcription) and it carries it into the cytoplasm, where it is translated by the ribosomes (during the translation to produce proteins. MESSENGER RNA (mRNA)

12. The ribosomal RNA (rRNA) is the structural component of ribosomes. It helps mRNA and tRNA come together in forming polypeptide chains RIBOSOMAL RNA (rRNA)

13. The transfer RNA (tRNA) transport specific amino acids from the cytoplasm to the ribosomes. The amino acids in the ribosomes are then joined together in proper order to make a chain of amino acids (polypeptide chains). TRANSFER RNA (tRNA)

14. MESSENGER RNA GETTING TO KNOW THE RNA TRANSFER RNA RIBOSOMAL RNA

15. GUIDE QUESTIONS 1. What are the three types of RNA that is responsible for the production of proteins? 2. How will you differentiate mRNA, rRNA, and tRNA?

16. PROTEIN SYNTHESIS Get to know...

17. PROTEIN SYTHESIS Protein synthesis is the creation of proteins by cells that uses DNA, RNA, and various enzymes. The process wherein the cells generate proteins is generally divided into two major steps: (1) transcription, and (2) translation.

18. TRANSCRIPT ME, PLEASE ACTIVITY 3

19. GUIDE QUESTIONS What tool did you use to unwind the DNA? How did you put the free nitrogenous bases? What is your answer in the DNA template that you have coded? How many strand/s of mRNA did you produce?

20. PRESENTATION TIME

21. TRANSCRIPT ME, PLEASE

22. GUIDE QUESTIONS What tool did you use to unwind the DNA? How did you put the free nitrogenous bases? What is your answer in the DNA template that you have coded? How many strand/s of mRNA did you produce?

23. TRANSCRIPTION CENTRAL DOGMA

24. It is a process wherein gene coding for a specific protein in the DNA is copied into the RNA. It happens inside the nucleus of a cell. TRANSCRIPTION

25. 3 STAGES OF TRANSCRIPTION INITIATION Initiation happens when RNA polymerase binds to a DNA strand. RNA POLYMERASE- enzyme responsible for opening the DNA molecule that will be transcribed.

26. 3 STAGES OF TRANSCRIPTION ELONGATION It enables the RNA polymerase to copy a single strand of DNA into a single-stranded RNA molecule-the messenger RNA of mRNA. In the process of transcription, complementary nucleotide bases are added.

27. 3 STAGES OF TRANSCRIPTION ELONGATION Instead of Thymine, Uracil will be paired with Adenine. A paired to U, G paired to C, or vice versa.

28. 3 STAGES OF TRANSCRIPTION TERMINATION The stage where DNA strand, mRNA and RNA polymerase dissociates with each other The produced mRNA will now go to cytoplasm to begin translation.

29. TRANSCRIPTION

30. PLAY ME LIKE RNA ACTIVITY 4

31. PLAY ME LIKE RNA Dr. Quack Quack Luksong Baka Luksong Tinik

32. PROCESS QUESTION What do you think is the stage of transcription have been shown in Dr. Quack-Quack, Luksong baka , and Luksong tinik ?

33. PLAY ME LIKE RNA

34. What do you think is the importance of transcription process in central dogma? VALUING How will you relate transcription process to your life as a student?

35. QUIZ TIME APPLICATION

36. What do you call to the process wherein gene coding for a specific protein in the DNA is copied into the RNA? A. Translation B. Replication C. Transcription D. Transformation QUESTION NO. 1

37. It contains genetic information from the DNA and it carries it into the cytoplasm, where it is translated by the ribosomes. A. transfer RNA B. messenger RNA C. massager RNA D. ribosomal RNA QUESTION NO. 2

38. Where does transcription process take place? A. Cytoplasm B. Golgi Bodies C. Nucleolus D. Nucleus QUESTION NO. 3

39. It is an enzyme that binds and opens the DNA molecule that will be transcribed. A. RNA Polymerase B. DNA Polymerase C. Helicase D. Primase QUESTION NO. 4

40. What is the correct order of the stages in transcription process? A. Elongation, Initiation, and Termination B. Initiation, Termination, and Elongation C. Initiation, Elongation. and Termination D. Termination, Elongation, and Initiation QUESTION NO. 5

41. Transcribe the DNA sequence below to form mRNA sequence DNA Strand Template: G G C T T A C G T A T C G TA mRNA:________________________________ FOR NUMBERS 6-10

42. ANSWER KEYS

43. What do you call to the process wherein gene coding for a specific protein in the DNA is copied into the RNA? A. Translation B. Replication C. Transcription D. Transformation QUESTION NO. 1

44. It contains genetic information from the DNA and it carries it into the cytoplasm, where it is translated by the ribosomes. A. transfer RNA B. messenger RNA C. massager RNA D. ribosomal RNA QUESTION NO. 2

45. Where does transcription process take place? A. Cytoplasm B. Golgi Bodies C. Nucleolus D. Nucleus QUESTION NO. 3

46. It is an enzyme that binds and opens the DNA molecule that will be transcribed. A. RNA Polymerase B. DNA Polymerase C. Helicase D. Primase QUESTION NO. 4

47. What is the correct order of the stages in transcription process? A. Elongation, Initiation, and Termination B. Initiation, Termination, and Elongation C. Initiation, Elongation. and Termination D. Termination, Elongation, and Initiation QUESTION NO. 5

48. Transcribe the DNA sequence below to form mRNA sequence DNA Strand Template: G G C T T A C G T A T C G TA mRNA: C C G A A U G C A U A G C A U FOR NUMBERS 6-10

49. THANK YOU!