Aliphatic amines part i

It contains about amines content which useful to II SEM B.PHARM & I PHARM D STUDENTS and dealing other organic chemistry profession ,life science students

1. ALIPAHTIC AMINES Unit-VI &POC I II SEM B.PHARM Aliphatic amines part I 06.07.2020 Presented by Mrs. Kavitha K Associate professor Department of pharmaceutical chemistry Karpagam college of pharmacy Coimbatore-32

2. Definition Amines are derivatives Of ammonia in which one or more hydrogen atoms have been replaced by alkyl or aryl groups

3. Classification of amines Primary amine:NH2(amino group)-A amine has only one alkyl group directly attached to the nitrogen Secondary amine: NH (imino group)- A amine has two alkyl group directly attached to the nitrogen atom. Tertiary amine: N(Tertiary nitrogen)-A amine has three alkyl group directly attached to the nitrogen atom

4. Nomenclature common system

5. IUPAC system

6. Structure of amines

7. Preparation of amines Reduction of nitro compounds Reduction of nitriles Reduction of oximes Reduction of amides Reductive amination of aldehydes & ketones Reduction of acyl halide

8. Reduction Of Nitro Compounds

9. Reduction of oximes

10. Reduction of nitriles & amides

11. Reaction of alkyl halides Hofmann”s method

12. Reductive amination of aldehydes & ketones

13. Reduction of acyl halides

14. From Phthalimide