Bambang Setiawan Department of Biochemistry and Molecular Biology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin, South Kalimantan, Indonesia Nucleic acid as biomolecule 1 Kuliah Biomedik PSKM 2020
Nucleotide functions Nucleic acid functions Energy for metabolisme (ATP) Enzyme cofactors (NAD + ) Signal transduction (cAMP) Storage of genetic info (DNA) Transmission of genetic infor (mRNA) Processing of genetic information (ribozymes) Protein synthesis (tRNA and rRNA) Nucleotide and nucleic acid 2 Kuliah PSIK AJ 2018
Kuliah PSIK AJ 2018 3
Nucleotide and nucleoside 4 Kuliah PSIK AJ 2018
Nucleotide and nucleoside 5 Kuliah PSIK AJ 2018
Pyrimidine bases Cytosine is found in DNA and RNA Thymine is found only in DNA (rarely in RNA) Uracil is found only in RNA (rarely in DNA) 6 Kuliah PSIK AJ 2018
Purine bases Adenine and guanine are found in both DNA and RNA 7 Kuliah PSIK AJ 2018
Nucleic acid Kuliah PSIK AJ 2018 8 They are polymers of four nucleotides. Linked by alternating sugar-phosphate bonds. They are: - RNA (ribonucleic acid) whose sugar is ribose - DNA (deoxyribonucleic acid) whose sugar is deoxyribose