Can the Standard of Care Be Elevated in Spondyloarthropathies? Key Learnings From Rheumacensus Initiatives in PsA and axSpA

Xenofon Baraliakos, MD, PhD, and Philip Helliwell, MD, PhD, discuss spondyloarthritis in this IME activity titled "Can the Standard of Care Be Elevated in Spondyloarthropathies? Key Learnings From Rheumacensus Initiatives in PsA and axSpA." For the full presentation, please visit us at www.peervoice.com/AFQ870.

1. PeerVoice

Can the Standard of Care Be Elevated in Spondyloarthropathies?
Key Learnings From Rheumacensus Initiatives in PSA and axSpA

Learning Objectives
Describe the rationale, design, and key areas of focus of the Rheumacensus
programmes in psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA)

Identify the overarching calls to action needed to implement a paradigm shift
designed to elevate health outcomes in patients with PsA and axSpA, as defined
by the Rheumacensus Consensus Council

Propose practical steps to elevate the standard of care for patients with PsA and
axSpA based upon results of the Rheumacensus Initiatives

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2. PeerVoice

Part 1 of 2: Elevating Standard of Care in PsA:
Gaining Consensus on Where We Should Focus

Philip Helliwell, MD, PhD
University of Leeds

Leeds, United Kingdom
Bradford Hospitals NHS Trust
Bradford, United Kingdom

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Disclosures
Philip Helliwell, MD, PhD, has a financial interest/relationship or affiliation
in the form of:

Consultant for Amgen Inc.
Honoraria from GRAPPA.

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Sub-Optimal Holistic Care
Delay in diagnosis and O
treatment initiation A r +
Lack of collaboration
between specialties
ical
pa

Improvements in
physical and

Disease activity social functioning,
outcomes work productivity

Disparity between
‘eatment targets

Patient
organisations

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Process of the Rheumacensus PsA Programme

Insights-gathering workshop Modified Delphi process
Stakeholder group leads (3 e-consultations)
1 patient representative, 4 patient representatives,
1HCP, 1 payor 4 HCPS, 4 payors

CC meeting
2 patient representatives,
2HCPs, 3 payors?

Shared area of focus |

Consensus statements | | Individual stakeholder CTA

¥

Overarching CTA
To elevate SoC for patients
with PsA

Themes

Narratives

al

* While some participants were absent

from the CC meeting, they provided
their responses separately by email or Consensus statements:
in an individual meeting. appropriate to inspire CTA

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Shared Areas of Focus and Key Themes

Patient
education and
sources of
information

Patient-HCP
consultations

Patient
empowerment

Optimal initial
treatment

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7. PeerVoice

Overarching Calls to Action for Theme 1

Improve the visibility of patients
and patient organisations to
bolster patient support and
strengthen the patient voice
at an organisational level
Support patients to understand

, life with a chronic condition and
Ensure all patients receive the y

HCPs to communicate
support they need to be effectively with patients so they
empowered

appreciate the patient's lived

experience

1. Patient Empowerment

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8. PeerVoice

Overarching Calls to Action for Theme 2

Direct patients to high-quality,
validated, easy-to-access
educational m:

Collaborate to develop tailored,

with patient input, covering th
full patient journey from
diagnosis with a chronic disease
through all life stages

the patient, to improve
knowledge of PsA among
dermatologists and the public

2. Patient Knowledge and Sources of Education

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9. PeerVoice

Overarching Calls to Action for Theme 3

Optimise patient involvement
in shared di on-making

Support HCP communication
techniques, including active
listening, motivational interviewing
and soft skills

Develop and utilise new and
existing tools to better prepare
patients for consultations

3. Patient-HCP Consultations

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): https://elearn.grappanetwork.org/

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10. PeerVoice

Overarching Calls to Action for Theme 4

Personalise treatment by
utilising assessment tools to
monitor patient treatment
journey and response
Improve collaboration and
engagement of payors with Adopt data, tools and algorithms
patients and patient organisations, to better understand drug
to augment a reciprocal comparisons and optimal
understanding of each other treatment
role and perspectives

4. Optimal Initial Treatment

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11. PeerVoice

Summary

a

Effective

and
across all stakeholders to
improve patient care

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12. PeerVoice

Abbreviations and References

Sub-Optimal Holistic Care
Abbreviation(s): QoL: quality of life.

Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.
Process of the Rheumacensus PsA Programme

Abbreviation(s): CC: Consensus Council; CTA: call to action; HCP: healthcare provider; PsA: psoriatic arthritis;
SoC: standard of care.
Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.

Shared Areas of Focus and Key Themes
Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.

Overarching Calls to Action for Theme 1
Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.

Overarching Calls to Action for Theme 2
Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.

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Abbreviations and References (Cont'd)

Overarching Calls to Action for Theme 3

Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi10.1007/540744-024-00664-3.
Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). GRAPPA Career Boost eLearning.
Effective clinical communication for improved outcomes 2023. https://elearn.grappanetwork.org/. Accessed 20 May
2024.

Overarching Calls to Action for Theme 4

Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024, doi:10.1007/540744-024-00664-3.

Summary
Reference(s): Verbinnen | et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00664-3.

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14. PeerVoice

Part 2 of 2: Actions to Elevate Standard of Care in axSpA:

Multistakeholder Consensus on Key Recommendations

Xenofon Baraliakos, MD, PhD
| Ruhr-University Bochum
} Bochum, Germany

Rheumazentrum Ruhrgebiet Herne

i } Herne, Germany

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Disclosures

Xenofon Baraliakos, MD, PhD, has no financial interests/relationships or
affiliations in relation to this activity.

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Sub-Optimal Holistic Care

First Symptoms: Disparity
dr Initiation of Comorbidities between
NEGIQUECISSRES, treatment = treatment
Lack of awareness targets

4 iveitis 'ypı N

Progressive HyBeriipidsenie
back pain Obesity

Morning
stiffness

Fatigue

Functional
impairment

(GC

Irreversible
structural damage of
the axial skeleton

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17. PeerVoice

Process of the Rheumacensus axSpA Programme

Insights-gathering workshop Modified Delphi process
Stakeholder group leads (3 e-consultations)
1 patient representative, 4 patient representatives,
1HCP, 1 payor 4HCPs, 4 payors

CC meeting
2 patient representatives,
3 HCPs, 4 payors®

Shared area of focus |

Consensus statements | | Individual stakeholder CTA

¥

Overarching CTA
To elevate SoC for patients
with axSpA

Themes

Narratives

“While some participants were absent
from the CC meeting, they provided Consensus statements
their responses separately by email. appropriate to inspire CTA

al

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18. PeerVoice

Shared Area of Focus
ET)

Personalised
ET) care

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19. PeerVoice

Overarching Calls to Action for Theme 1

Audit currently available patient
empowerment measures and
tailor these to

Make patients aware of th:
in their care and
support them to voice their

before
implementation in the clinic

y ©

experience, ask questions, and
state their treatment goals

Patient Empowerment

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20. PeerVoice

Overarching Calls to Action for Theme 2

Provide patients with

, tailored to their
, on any aspect of
living with axSpA that interests
them (including clinical, holistic, and
health economic topics)

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Patient Knowledge

Forge collaborations between HCPs
and patient representatives to

high-quality information
to patients and become the
recognised sources of
information

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21. PeerVoice

Overarching Calls to Action for Theme 3

to the patient's
lived experience of axSpA and
take this into account, rather
than solely using laboratory
results/clinical findings to guide
management

Collaborate with specialist
rheumatology nurses to ascertain
patients’ needs to
inform and set tailored treatment
goals

Structure and tailor
consultations according to
e patient's agenda to

Support patients to

with HCPs patient

and reach a shared
treatment decision

Patient-HCP Consultations

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Overarching Calls to Action for Theme 4

Raise pharmacist
awareness of the effects
of non-consensual
switching to a biosimilar
Involve the t
in formulary
committees and guideline
development

Optimal Initial Treatment

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Ensure equity of
timely access to biologics
across regions

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23. PeerVoice

Summary

Patient empowerment

4

decision-making

Effective wr

la tion, and edu:

across all stakeholders to
improve patient care

and timely of
appropriate treatment choices

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24. PeerVoice

Abbreviations and References

Sub-Optimal Holistic Care
Abbreviation(s): IBD: inflammatory bowel disease.

Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/540744-024-00663-4.
Process of the Rheumacensus axSpA Programme

Abbreviation(s): axSpA: axial spondyloarthritis; CC: Consensus Council; HCP: healthcare provider; SoC: standard of
care.
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/540744-024-00663-4.

Shared Area of Focus
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/540744-024-00663-4.

Overarching Calls to Action for Theme 1
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/540744-024-00663-4.

Overarching Calls to Action for Theme 2
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00663-4.

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25. PeerVoice

Abbreviations and References (Cont'd)

Overarching Calls to Action for Theme 3
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/s40744-024-00663-4.

Overarching Calls to Action for Theme 4
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi:10.1007/540744-024-00663-4.

Summary
Reference(s): Phoka A et al. Rheumatol Ther. Published online 25 April 2024. doi10.1007/540744-024-00663-4.

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