Plan
4
Definition/Aimof CardiopulmonaryResuscitation(CPR)
Treatment of VF / PulselessVT
Treatment of non-VF/VT rhythm
Potential reversible causes of cardiac arrest
Airway, IV Access, Drugs
CardiopulmonaryResuscitation
(CPR) -Definition
5
Emergentmedicalapplicationsthatareperformedfora living
whoserespiratoryandcirculationfunctionshavebeenstopped
in an immediateandunexpectedstatus
9
CPR –ILCOR (InternationalLiaisonCommitteeOn Resuscitation)
American Heart Association (AHA)
European Resuscitation Council (ERC)
Heart and Stroke Foundation of Canada (HSFC)
Australian Resuscitation Council (ARC)
Resuscitation Councils of Southern Africa (RCSA)
Council of Latin America for Resuscitation (CLAR)
10
CPR
Basic Life Support
Advanced Life Support
Prolonged Life Support
11
CPR
Basic Life Support
Advanced Life Support
Prolonged Life Support
12
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
•Correct reversible causes
•Check electrode position and
contact
•Attempt / verify:
IV access
airway and oxygen
•Give uninterrupted
compressions when airway
secure
•Give adrenaline every 3-5 min
•Consider:amiodarone,
atropine,
magnesium
Immediately resume
CPR 30:2
for 2 min
AdultALS
Algorithm
13
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
•Correct reversible causes
•Check electrode position and
contact
•Attempt / verify:
IV access
airway and oxygen
•Give uninterrupted
compressions when airway
secure
•Give adrenaline every 3-5 min
•Consider: amiodarone,
magnesium
Immediately resume
CPR 30:2
for 2 min
AdultALS
Algorithm
14
Open Airway
Look for signs of life
…. to confirm cardiac arrest
Patient response
Open airway
Check for normal breathing
(caution agonalbreathing)
Check circulation
Monitoring
15
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
•Correct reversible causes
•Check electrode position and
contact
•Attempt / verify:
IV access
airway and oxygen
•Give uninterrupted
compressions when airway
secure
•Give adrenaline every 3-5 min
•Consider: amiodarone,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
16
Open Airway
Look for signs of life
Call
Resuscitation
Team
Cardiac arrest confirmed
CPR 30:2
Until defibrillator /
monitor attached
18
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
•Correct reversible causes
•Check electrode position and
contact
•Attempt / verify:
IV access
airway and oxygen
•Give uninterrupted
compressions when airway
secure
•Give adrenaline every 3-5 min
•Consider: amiodarone,
atropine,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
19
Adult ALS
Algorithm
Open Airway
Look for signs of life
Call
Resuscitation
Team
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/PulselessVT)
Non-shockable
(PEA/Asystole)
20
Adult ALS
Algorithm
Open Airway
Look for signs of life
Call
Resuscitation
Team
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/PulselessVT)
Non-shockable
(PEA/Asystole)
CARDİAC ARREST RHYTHMS
1.VentricularFibrillation(VF)
2.PulselessVentricularTachicardia(VF)
3.Asystole
4.PulselessElectricalActivity(PEA)
Precordial Thump
Rapid treatment of a
witnessed and monitored
VF/VT cardiac arrest
Used if defibrillator not
immediately available
?
1
st
shock
150 -200 J biphasic
360 J monophasic
Assess
Rhythm
Shockable
(VF/Pulseless VT)
1 Shock
150-360 J biphasic
or 360 J monophasic
Immediately resume
CPR 30:2
for 2 min
Defibrillation Energies
Vary with manufacturer
Check local equipment
If unsure, deliver 200 J (do not delay shock)
Deliver 2
nd
shock
Deliver 3
rd
shock
CPR for 2 min
If VF/VT persists
CPR for 2 min
Deliver 4
th
shock
Adrenalin,1mg iV
Amiodaron, 300 mg
2
nd
and subsequent shocks
Max. (270-360J)biphasic
360 J monophasic
Minimise delays between CPR
and shocks (< 10 s)
After delivery of shock
Continue CPR for another 2 min
stop CPR only if patient shows signs of life
After 2 min, assess rhythm:
If organised electrical activity, check for signs of life:
if ROSC start post resuscitation care
if no ROSC go to non VF/VT algorithm
If asystole, go to non VF/VT algorithm
Asystole
Pulseless Electrical
Activity (PEA)
Assess
Rhythm
Non-shockable
(PEA/Asystole)
Immediately resume
CPR 30:2
for 2 min
Absent ventricular (QRS) activity
Atrial activity (P waves) may persist
Rarelya straight line trace
Treat fine VF as asystole
Non-shockable
(Asystole)
Asystole
During CPR:
check leads are attached
adrenaline 1 mg IV every 3 –5 min
Clinical features of cardiac arrest
ECG normally associated with an output
Non-shockable
(PEA)
Pulseless Electrical Activity
(PEA)
Exclude/treat reversible causes
Adrenaline 1 mg IV every 3-5 min
During CPR:
Correct reversible causes
Check electrode position and contact
Attempt / verify:
-IV access
-Airwayand oxygen
Give uninterrupted compressions when airway
secure
Give adrenaline every 3-5 min
Consider: amiodarone, magnesium
Airway and Ventilation
Secure airway:
tracheal tube
supraglottic airway device
e.g. LMA
Once airway secured, if possible, do not
interrupt chest compressions for ventilation
Avoid hyperventilation
Intravenous Access
Peripheral versus central veins
Intraosseous Access
TRACHEAL ACCESSx
Drugs
Adrenaline
Amiodarone
Magnesium
Thrombolytics
Sodium bicarbonate
O
2
Adrenaline
Actions:
agonistarterial vasoconstriction
systemic vascular resistance
cerebral and coronary blood flow
agonistheart rate
force of contraction
myocardial O
2demand
(may increase ischaemia)
Adrenaline
Indications:
During cardiac arrest
VF/VT –give after3
rd
shock
Non VF/VT –give immediately
Repeat every 3-5 min
1 mg IV
Cautious use after ROSC
Amiodarone
Actions:
Lengthens duration of action potential
Prolongs QT interval
Mild negative inotrope -may cause
hypotension
Amiodarone
Indications:
Shock refractory VF/VT
300 mg IV
Give after 3
rd
shock
If unavailable give lidocaine 1.5mg/kgIV
Atropine
Indications:
Peri-arrest
Symptomatic sinus, atrial or nodal bradycardia
500 mcg IV increments to 3 mg
Magnesium
Hypomagnesaemia often co-exists with
hypokalaemia
Actions:
Depresses neurological and myocardial
function
A physiological calcium blocker
Magnesium
Indications:
VF / VT with hypomagnesaemia
Torsade de pointes
Atrial fibrillation
Digoxin toxicity
Dose:
cardiac arrest 2 g (8 mmol) IV bolus
peri-arrest 2 g (8 mmol) IV over 10 min
Thrombolytic Drugs
Actions:
Dissolves thrombus
Improves cerebral blood flow
Has a role in coronary thrombosis and
pulmonary embolism
Thrombolytic Drugs
Indications:
Cardiac arrest caused by suspected pulmonary
embolus
Can take up to 60 min to have effect
Dose:
Tenecteplase500-600 mcg kg
-1
IV over 10 sec
Alteplase(rt-PA) 10 mg IV over 1-2 min followed
by IV infusion of 90 mg over 2 h
Sodium Bicarbonate
Indications:
Life-threatening hyperkalaemia
Tricyclic overdose
Severe metabolic acidosis (pH < 7.1)
Dose:
50 ml 8.4% sodium bicarbonate IV
Summary
•ALS algorhythm provides a standardised approach to
cardiac arrest treatment
•Shockable rhythms (VF/pulseless VT)
•Non-shockable rhythms (Asystole, PEA)
•Reversible reasons of cardiac arrest (4H,4T)
LAST WORDS
Drugs role in cardiac arrest becomes after
effective chest compression, effective ventilation
with high oxygen concentration and defibrillation