Drug for dermatology student, Sultan.ppt

Drugs for dermatologu disorders for students

1. 1
Chapter 50
Drugs for Dermatologic Disorders
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

2. 2
Causes of Skin Lesions
Acne vulgaris
Psoriasis
Eczema dermatitis
Contact dermatitis
Drug-induced dermatitis
Burn infections
Viral infections
Herpes simplex, herpes zoster
Fungal infections
Tineapedis, tineacapitis
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

3. 3
Types of Skin Lesions
Macules
Papules
Vesicles
Plaques
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

4. 4
Acne Vulgaris
Characteristics
Nonpharmacologicapproach
Antiacnedrugs
Keratolytics
•Benzoyl peroxide
•Resorcinol
•Salicylic acid
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

5. 5
Acne Vulgaris (Cont.)
Antiacnedrugs
Topical
•Tretinoin(Retin-A, Renova)
•Adapalene(Differin)
•Azelaicacid (Azelex)
•Tazarotene(Tazorac)
Oral antibiotics
•Doxycycline
•Minocycline
•Tetracycline
•Erythromycin
Topical glucocorticoids
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

6. 6
Acne Vulgaris (Cont.)
Antiacnedrugs
Systemic: isotretinoin(Amnesteem)
•Side effects of isotretinoin
Skin irritation, thrombocytopenia, nosebleeds, teratogenic
effects
•Monitoring of blood work
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

7. 7
iPLEDGE
Risk management program for isotretinoin
Includes implications for
Patient
Health care provider
Pharmacist
Wholesaler
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

8. 8
Psoriasis
Characteristics
Psoriasis drug treatment
Topical: Salicylic acid, sulfur, topical
glucocorticoids, anthralin(Psoriatec), calcipotriene
(Dovonex), tazarotene(Tazorac), and coal tar
(Scytera)
Ultraviolet light
Systemic: Methotrexate
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

9. 9
Psoriasis (Cont.)
Biologic agents
Alefacept(Amevive)
Etanercept(Enbrel)
Infliximab (Remicade)
Adalimumab(Humira)
Ustekinumab(Stelara)
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

10. 10
Verruca Vulgaris (Warts)
Characteristics
Drugs for treatment
Salicylic acid
Podophyllumresin
Imiquimod(Aldara, Zyclara)
Podofilox(Condylox)
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

11. 11
Nursing Process: Acne Vulgaris and
Psoriasis
Assessment
Nursing diagnosis
Planning
Nursing interventions
Patient teaching
Cultural considerations
Evaluation
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

12. 12
Drug-Induced Dermatitis
Characteristics
Rash, urticaria, papules, and vesicles
Life-threatening: erythema multiforme(red blisters
over a large portion of the body), Stevens-
Johnson syndrome (large blisters in the oral and
anogenitalmucosa, pharynx, eyes, and viscera),
toxic epidermal necrolysis(widespread
detachment of the epidermis from underlying skin
layers)
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

13. 13
Drug-Induced Dermatitis (Cont.)
Etiology
Penicillin hypersensitivity
Toxic epidermal necrolysis
Discoid lupus erythematosus (DLE)
Exfoliativedermatitis
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

14. 14
Contact Dermatitis
Characteristics
Causes
Chemical: cosmetics, perfume
Plants: poison ivy
Nonpharmacologicmeasures
Pharmacologic measures
Burow’ssolution (aluminum acetate)
Calamine lotion
Glucocorticoid ointments, creams, or gels
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

15. 15
Impetigo
Etiology
Population affected
Treatment
Topical
Systemic
•Mupirocin(Bactroban)
•Retapamulin(Altabax)
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

16. 16
Hair Loss and Baldness
Etiology
Family history
Aging
Drug-induced
Febrile illnesses
Pregnancy
Myxedema
Treatment
Minoxidil(Rogaine)
Finasteride(Propecia, Proscar)
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

17. 17
Sunscreens
Categories of sunscreen
Chemical
Physical
Sun protective factor (SPF)
UVB radiation
Preventive measures
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

18. 18
Burns and Burn Preparations
Degrees of burns
Topical drugs for burns
Mafenide(SulfamylonCream)
•Side effects/adverse reactions
Burning sensations, blistering, superinfection, acidosis
Silver sulfadiazine (Silvadene)
•Side effects
Skin discoloration
Silver nitrate 0.5% solution
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

19. 19
Nursing Process: Burns
Assessment
Nursing diagnoses
Planning
Nursing interventions
Patient teaching
Cultural considerations
Evaluation
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

20. 20
Practice Question #1
Finasteride(Propecia) is used to treat male
pattern baldness. The nurse knows that in
higher doses, the drug is used to treat which
condition?
A.Benign prostatic hypertrophy
B.Gastroesophagealreflux
C.Migraine headache
D.Impotence
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

21. 21
Practice Question#2
A patient is ordered to receive isotretinoin
(Amnesteem) for acne vulgaris. What is
considered priority information in teaching
this patient?
A.Good skin hygiene
B.Optimal nutritional practices
C.Contraception or abstinence from sexual
intercourse
D.Methods to avoid infection
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

22. 22
Practice Question#3
A patient is admitted to the emergency
department with a burn that consists of
pearly white skin with areas that are
charred. The patient is not in pain. The
nurse documents the burn as
A.superficial epidermal.
B.partial thickness superficial.
C.deep thickness.
D.full thickness.
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

23. 23
Practice Question#4
Patients receiving extensive amounts of
mafenideacetate (SulfamylonCream) for
the treatment of burns are most at risk for
the development of which imbalance?
A.Hypomagnesemia
B.Metabolic acidosis
C.Respiratory acidosis
D.Hypocalcemia
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.

24. 24
Practice Question#5
Which medication does the nurse anticipate
administering to a patient with venereal warts?
A.Salicylic acid
B.Podophyllumresin
C.Etanercept
D.Anthralin
Copyright © 2015, 2012, 2009, 2006, 2003, 2000, 1997, 1993 by Saunders, an imprint of Elsevier Inc.