Gastric cancer has a significant impact in India, considering its large population and diverse socioeconomic factors. Here's an overview of the impact: Epidemiology: Incidence: 10-15 per 100,000 population (higher in North-East India and coastal regions) Mortality: 8-12 per 100,000 population Ranked 3rd among cancers in India (after breast and lung cancer)4. Age-standardized incidence rate (ASR): 11.1 per 100,000 (men) and 6.8 per 100,000 (women)
Regional Variations: 1. North-East India: Higher incidence due to dietary habits (e.g., fermented fish) 2. Coastal regions: Higher incidence due to dietary habits (e.g., high salt intake) 3. Urban areas: Higher incidence due to lifestyle factors (e.g., smoking, obesity) Socioeconomic Factors: Low socioeconomic status: Increased risk due to poor nutrition and healthcare access Education: Lower levels of education associated with higher incidence Occupation: Increased risk among those with high-stress jobs or exposure to carcinogens
Healthcare Challenges: 1. Limited access to screening and early detection 2. Inadequate healthcare infrastructure in rural areas 3. Delayed diagnosis and treatment 4. High treatment costs Economic Burden: 1. Estimated annual healthcare cost: ₹5,000-7,000 crores (~ $750-1 billion USD) 2. Loss of productivity: ₹10,000-15,000 crores (~ $1.5-2.2 billion USD) 3. Indirect costs (e.g., travel, food): ₹5,000-10,000 crores (~ $750-1.5 billion USD)
Government Initiatives: 1. National Cancer Control Programme (NCCP) 2. National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) 3. Ayushman Bharat Yojana (ABY) Recommendations: 1. Improve screening and early detection 2. Enhance healthcare infrastructure 3. Increase awareness and education 4. Promote healthy lifestyle habits 5. Implement effective treatment and palliative care
Research Focus: 1. Genetic predisposition 2. Dietary and lifestyle factors 3. Helicobacter pylori (H. pylori) infection 4. Biomarkers for early detection 5. Targeted therapies and immunotherapy Sources:- Indian Council of Medical Research (ICMR) National Centre for Disease Control (NCDC) World Health Organization (WHO) International Agency for Research on Cancer (IARC National Cancer Registry Programme (NCRP)