Handbook Of Oxidative Stress In Cancer Therapeutic Aspects Sajal Chakraborti

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Handbook Of Oxidative Stress In Cancer Therapeutic Aspects Sajal Chakraborti
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects Sajal Chakraborti
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects Sajal Chakraborti


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Handbook of
Oxidative Stress in
Cancer: Therapeutic
Aspects
Sajal Chakraborti
Editor

Handbook of Oxidative Stress in Cancer:
Therapeutic Aspects

Sajal Chakraborti
Editor
HandbookofOxidative
StressinCancer:
TherapeuticAspects
With 552 Figures and 239 Tables

Editor
Sajal Chakraborti
Department of Biochemistry and Biophysics
University of Kalyani
Kalyani, West Bengal, India
ISBN 978-981-16-5421-3 ISBN 978-981-16-5422-0 (eBook)
https://doi.org/10.1007/978-981-16-5422-0
© Springer Nature Singapore Pte Ltd. 2022
This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether
the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of
illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and
transmission or information storage and retrieval, electronic adaptation, computer software, or by
similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication
does not imply, even in the absence of a specific statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book
are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the
editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors
or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims
in published maps and institutional affiliations.
This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd.
The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721,
Singapore

“Only a life lived for others is a life
worthwhile”–Albert Einstein
Volume 1 is dedicated to:
Mr. Sonu Sood(Film actor and
Philanthropist), who helped millions of
Indians amid the COVID crisis
Mr. Ajay Edward, who had converted the
iconic Glenary’s Bakery, Cafe and Restaurant
to an isolation center amid the COVID crisis
in Darjeeling, West Bengal, India
Red Volunteers, who made a mark amid the
COVID crisis in West Bengal, India
Dr. Abhijit Vinayak Banerjee, Dr. Esther
Duflo and Dr. Michael Kremer(winner of
2019 Nobel Prize in Economic Sciences) for
their experimental approach to alleviating
global poverty
The Three hundred forty three (343)
firefighters of the New York City Fire
Department, who died while fulfilling their
duties at the World Trade Center on
September 11, 2001
Volume 2 is dedicated to:
Dr. Kalyan K Sarkar, Woodlands Hospital,
Kolkata, India

Dr. Arunava Sengupta, Apollo Gleneagles
Hospital, Kolkata, India
Dr. Saradindu Ghosh, Saroj Gupta Cancer
Center and Research Institute, Kolkata, India
Dr. Sanjoy K Maity, Gandhi Memorial
Hospital, Kalyani, West Bengal, India
Dr. Subrata Nag, SSKM Hospital, Kolkata,
India
Volume 3 is dedicated to:
Dr. Gerry Shaw, University of Florida,
Gainesville, Florida, USA
Dr. Malay Ghosh, University of Florida,
Gainesville, Florida, USA
Dr. Pradip K Bose, University of Florida,
Gainesville, Florida, USA
Dr. Dilip K Nag, Wadsworth Center, New York
State Department of Health, Albany,
New York, USA
Late Dr. Prahlad C Ghosh, University of
Delhi, South Campus, New Delhi, India
Volume 4 is dedicated to:
Dr. Siddhartha Das, University of Texas,
El Paso, Texas, USA
Late Dr. Gail H Gurtner, Post-doctoral
supervisor of the editor at the Johns Hopkins
Medical Institution, Baltimore, Maryland,
USA
Dr. John R Michael, Post-doctoral
supervisor of the editor at the University of
Utah Health Sciences Center, Salt Lake City,
Utah, USA
Dr. Ernst W Spannhake, The Johns Hopkins
Bloomberg School of Public Health,
Baltimore, Maryland, USA
Dr. Terry Adams, The Johns Hopkins
Bloomberg School of Public Health,
Baltimore, Maryland, USA

Volume 5 is dedicated to:
Late Swadesh Ranjan Chakraborty. Father
of the editor
Bina Chakraborty. Mother of the editor
Late Samar Ranjan Chakraborty. Elder
brother of the editor

Preface
The aim of science is not to open the door to infinite wisdom, but to set a limit to
infinite error”
Bertolt Brecht–Life of Galileo
Cancer is the term used for diseases that affect any organ in the body, in which
abnormal cells divide in an uncontrolled manner and in some instances can invade
other tissues. Cancer is not just one disease but many diseases with origins in
multiple organ systems. The defining abnormality in cancer is an imbalance between
cell proliferation and normal cell death and is caused by mutations in DNA. Genes
that promote cell growth in tumors are called proto-oncogenes, while tumor sup-
pressor genes code for proteins that mediate anti-proliferation signals and suppress
mitosis and cell growth. Everyone has proto-oncogenes in their body, which can
cause cancer only when a mutation occurs in the gene that results in the gene being
permanently turned on. To describe it poetically, one may cite from a verse of
Sankha Ghosh (a noted Bengali poet):Those who are calm and feeble may in
some situations become frenzy. Upregulation of proto-oncogenes and/or down-
regulation of tumor suppressor genes are common events in cancer.
This book was aimed at (i) introducing basic cellular and molecular concepts to
biomedical researchers to promote collaboration and foster much-needed transla-
tional research and (ii) introducing emerging concepts and approaches of therapeu-
tics in cancer research to the clinical researchers. To accomplish these goals, the
book covers different sections ranging from therapeutic potentialities of natural and
synthetic compounds in the clinical management of metastatic diseases to the system
biology approach to gain insights into the mechanisms of cancer progression and
metastasis. Some of the additional sections covered include radiation and photody-
namic approaches, stem cell therapy, nanotechnology-based therapy and epigenetic
tools, and gene therapy.
The chapters in this book are well-organized themes and are supplemented with
tables and graphics, highlighting the most recent information that aims at determin-
ing therapeutics of different types of cancers. We hope that this book will stimulate
especially young biomedical researchers and graduate students to take up further
investigations on the therapeutics of different types of cancers.
ix

Thanks are due to all contributors for the considerable energy, time, and effort that
they spent in making this book an advancement of knowledge for understanding
therapeutic aspects of oxidative stress-induced cancer. Finally, we thank Mr. Jacob
Arun Raj and Ms T. Rajeswari of Springer Nature for their assistance during the
preparation of the book.
Kalyani, India Sajal Chakraborti
September 2022 Editor
x Preface

Contents
Volume 1
Part I Therapeutic Implications of Natural Compounds......... 1
1 Elimination of Senescent Cells by Polyphenols and
Flavonoids........................................... 3
A. Kühnel Harald
2 Natural Dietary Alkaloids and Its Synthetic Derivatives as
Oxidative Stress-Inducing Agents for Cancer Therapy........ 25
Preksha Shahagadkar and Gnanasekar Munirathinam
3 Natural Therapeutic Strategies for Modulating Oxidative
Stress in Cancer...................................... 39
Gabriela Henríquez and Mahesh Narayan
4 Antioxidant in Cancer.................................. 65
Khushnuma Wahabi, Ahmad Perwez, and Moshahid A. Rizvi
5 Antioxidant Activity of Phytochemicals in Cancer............ 81
Shreyas R. Gaikwad and Sanjay K. Srivastava
6 Therapeutic Application of Microbial Metabolites in Free
Radical–Induced Tumorigenesis.......................... 99
Indranil Chattopadhyay
7 Therapeutic Potential of Natural Agents Against Oxidative
Stress-Influenced Colitis-Associated Cancer................. 115
Aarthy Venkatesan, Saabira Banu Sahubar Sadik, Prathibha
Sivaprakasam, Mohamed A. Adil, Karthikeyan Chandrabose,
Suresh Kumar Anandasadagopan, and Ashok Kumar Pandurangan
8 Oxidative Stress: A Double Edged Sword in Cancer.......... 135
Bhagya N. and Chandrashekar K. R.
xi

9 Prevention of Fertility due to Chemotherapy-Induced
Ovarian Failure: Role of Therapeutic Antioxidants........... 153
Rauf Melekoglu, Umran Karabulut Dogan, Nesibe Zeyveli Celik,
and Ercan Yilmaz
10 Therapeutic Implications of Phytochemicals in ROS-Induced
Cancer.............................................. 173
Dhan Prakash and Charu Gupta
11 Nutraceuticals in Cancer Therapy........................ 189
Shaimaa Fayez, Iriny M. Ayoub, Nada M. Mostafa,
Ashaimaa Y. Moussa, Mariam I. Gamal ElDin, and
Mohamed El-Shazly
12 Potential Natural Product–Derived Compounds for
Lung Cancer Therapy.................................. 209
Pithi Chanvorachote, Pilaiwanwadee Hutamekalin,
Preedakorn Chunhacha, and Zin Zin Ei
13 Role of Dietary Antioxidants in Chemoprevention of
Nitrosamines-Induced Carcinogenesis..................... 253
Uju Dorathy Iliemene Ejike and Mubarak Labaran Liman
14 Natural Antioxidants for the Prevention and
Treatment of Cancer................................... 277
Oana Cioanca, Ionela-Daniela Morariu, and Lucian Hritcu
15 Protective Effect of Quercetin, Luteolin, and Fisetin via
Stimulating the p53-Mediated Signaling in Cancer........... 291
Johirul Islam
16 Flavonoids and Its Anticancer Activity for ROS-Induced Breast
Cancer.............................................. 305
Mayuri Dholaria
17 Role of Indian Ginseng Withaferin A in ROS-Induced Cancer
Chemoprevention and Cancer Therapy.................... 327
Padala Krishna Mounica, Geetanjali Devabattula, and
Chandraiah Godugu
18 Role of Carotenoids in Preventing Oxidative
Stress–Induced Cancer................................. 351
Edakkadath Raghavan Sindhu, Antholi Keloth Kavya, and
Ponnamparambil Purushothaman Binitha
19 Role of Honey in Prevention and Management
of Cancer............................................ 365
Neeladrisingha Das, Chandrachur Ghosh, Surender Saini,
B. L. Saraswat, and Partha Roy
xii Contents

20 Natural Extracts Target NF-κB and Reactive
Oxygen Species....................................... 387
Manas K. Mahapatra and Chandi C. Mandal
21 Natural Compounds fromPlumbago zeylanicaas Complementary
and Alternative Medicine............................... 415
Khalida Bloch, Vijay Singh Parihar, Minna Kellomäki, and
Sougata Ghosh
22 Immunomodulatory Algal Metabolites for Alleviating
Inflammation and Cancer............................... 443
Sriram Srinivasan, Prisilla Arockiasamy, Daniel A. Gideon,
Saravanan Sekaran, Harini Arumugasamy, and Naveen Kumar
Devanga Ragupathi
23 Targeting Natural Compounds to Mitochondria as a
Novel Strategy for Cancer Therapy....................... 465
Rahul Checker, Debojyoti Pal, Deepak Sharma, and
Santosh K. Sandur
24 Recent Updates on the Bioactive Compounds of Ginger
(Zingiber officinale) on Cancer: A Study with Special
Emphasis of Gingerol and Its Anticancer Potential........... 489
Kondeti Ramudu Shanmugam, Bhasha Shanmugam, Gangikunta
Venkatasubbaiah, Sahukari Ravi, and Kesireddy Sathyavelu Reddy
25 Cytotoxic, Antitumor, and Chemopreventive Effects of
Pointed Gourd (Trichosanthes dioica) Root................. 507
Sanjib Bhattacharya
26 Therapeutic Implications of Piperlongumine................ 525
Krushnamurthy PH, Simita Das, Dhananjaya G, and
Nilkamal Mahanta
27 Antioxidant/Pro-oxidant, Anti-inflammatory, and
Immunomodulatory Effects of Thymoquinone in Cancer
Prevention and Treatment............................... 547
Abdurrahim Kocyigit and Eray Metin Guler
28 Therapeutic Implications of Spirulina in ROS-Induced Cancer
Progression.......................................... 561
Huriye Senay Kiziltan
29 The Role of Cannabis Species on Oxidative Stress in
Cancer Cells......................................... 581
Dimakatso Mokoena, Blassan P. George, and Heidi Abrahamse
Contents xiii

30 Natural Chemopreventive Agents for the Treatment and
Prevention of Oral Squamous Cell Carcinoma............... 595
Viji Remadevi, Juberiya M. Azeez, Vini Ravindran,
Sreeharshan Sreeja, Anjana Sasikumar Sujatha, and
Saifudeen Ismael
31 Phytochemicals as Pro-oxidants in Cancer.................. 611
Sailendra Kumar Mahanta and Siva Reddy Challa
32 Protective Role of Pomegranate in ROS-Induced
Prostate Cancer....................................... 621
Tapati Chakraborti, Dibyapriya Roychowdhury, Soni Shaikh,
Suman Kumar Nandy, and Sajal Chakraborti
33 The Effect of Oxidative Nutritional Products on
Cancer.............................................. 637
Takehiko Takayanagi
34 Natural Products as an Alternative Therapy for
Brain Tumors........................................ 653
Sachin Kumar, Mandeep Kumar, Anjali Bijalwan, Shubham Sharma,
and Puneet Kumar
35 Current Evidence and Future Perspectives About
Herbal Therapeutics for Cancer Therapy.................. 679
David Paul, A. Parag, K. S. Aswathi, Dinesh Kumar Chellappan,
Somasundaram Arumugam, and Satheesh Kumar Nanjappan
36 Herbal Remedies for Improving Cancer Treatment
Through Modulation of Redox Balance.................... 709
Sukhchain Kaur, Harkomal Verma, Sharanjot Kaur, Subham Singh,
Anil K. Mantha, and Monisha Dhiman
37 Targeting Redox Homeostasis of Tumor Cells by Therapeutic
Compounds in Cancer.................................. 727
Kanika Vasudeva, Pragya Chaturvedi, Rahul Khan, Prachi Sahu, and
Anjana Munshi
38 Natural Compound-Based Nanoparticles to Target Free
Radicals in Cancer.................................... 745
Umesh Prasad Yadav, M. Rhuthuparna, Kanika Vasudeva, Prabhat
Suman, Anjana Munshi, Santosh Kumar, and Sandeep Singh
Part II Therapeutic Implications of Synthetic Compounds . ..... 759
39 Small Molecule Inhibitors That Target Signal Transduction
Pathways Involved in Oxidative Stress-Induced Cancer....... 761
Naveen Kumar Perumal, Nivya Vijayan, Madan Kumar Perumal,
Devaraj Halagowder, and Niranjali Devaraj Sivasithamparam
xiv Contents

40 Pristimerin in Oxidative Stress and Use in Cancer........... 775
Ana Carolina B. da C. Rodrigues, Sara P. Neves,
Carlos V. A. da Silva, Felipe M. A. da Silva, Emmanoel V. Costa,
Hector H. F. Koolen, and Daniel P. Bezerra
41 Polyphenolic Acetates as Potential Therapeutics and
Adjuvant in Radiotherapy of Cancer...................... 799
Kavya Venkateswaran, Amit Verma, and Bilikere S. Dwarakanath
42 Applications of Peptide in Cancer Therapy................. 817
Soumi Biswas and Jishu Naskar
43 The Influence of Protein Disulfide Isomerase Inhibitors
on Oxidative Stress in Breast Cancer Metastasis............. 833
Maria Walczak
44 Beyond Natural Antioxidants in Cancer Therapy: Novel
Synthetic Approaches in Harnessing Oxidative Stress......... 845
Hichem Moulahoum, Faezeh Ghorbanizamani, Suna Timur, and
Figen Zihnioglu
45 Arylboronic Acids and Ester-Based Prodrugs Targeting
Oxidative Stress in Cancer.............................. 863
Md Yousuf, Aasia Ansari, and Rajkumar Banerjee
46 An Overview of Antioxidative Anticancer Therapies with
Reference to the Cancer Stem Cells....................... 885
Subhajit Chatterjee, Chandragouda R. Patil, and Chanakya Nath
Kundu
47 Application of Stimuli-Responsive Polymers in
Cancer Therapy...................................... 909
Parvati Sharma, Asha Poonia, Monika Jangra, and Ankur
48 Evaluation of the Anticancer Activities of Isatin-Based
Derivatives........................................... 923
Daniel A. Gideon, Pushparaj Annadurai, Vijay Nirusimhan,
Abhinav Parashar, Joel James, and V. Violet Dhayabaran
49 Efficacy of Synthetic Organic Molecule Inhibitors of
TRAF2 and NCK-Interacting Kinase (TNIK) Against
Colorectal Cancer..................................... 949
Jesucastin Edward, Karthik Sudarsha, J. Jeyakanthan,
A. Sherlin Rosita, and Daniel A. Gideon
50 Recent Advances in the Development of Synthetic Pro-oxidants:
Implications for ROS-Based Cancer Therapeutics............ 977
Sailendra Kumar Mahanta and Hemant Kumar Sharma
Contents xv

51 Synthetic Small Molecules in Prostate Cancer
Therapeutics......................................... 985
Binil Eldhose and Gartrell C. Bowling
52 Therapeutic Efficacy of Roscovitine Against Cancer..........1005
Sarita Das
53 Oxidative Stress Modulation by G-quadruplex
Binder-Naphthalene Diimide Derivatives and Its
Therapeutic Potential..................................1027
Sumiran Kumar Gurung, Sangeeta Kumari, and Neelima Mondal
54 A Critical Appraisal of Current Status of Synthetic
Antioxidant Molecules in the Treatment of
Breast Cancer........................................1047
Kuldeep Kumar, Akashdeep Singh Pathania, Dhandeep Singh,
Dimple Sethi, Amteshwar S. Jaggi, and Nirmal Singh
Volume 2
Part III Radiation and Photodynamic Approaches in
ROS-Induced Cancer Therapeutics...........................1087
55 Modulatory Effects of Stem Cells on Oxidative Stress and
Antioxidant Defense System in Cancer.....................1089
Osama M. Ahmed, Noha A. Ahmed, Nour Y. S. Yassin, and
Eman R. Abd Elhaliem
56 Emerging Interdisciplinary Techniques to Extend ROS
Modulation for the Benefit of Chemo-/Radiotherapy
in Cancer............................................ 1105
Sunder Singh, Rakesh Dhankhar, Anil K. Dhull, and Kiran Dahiya
57 Photodynamic Therapy-Induced Oxidative Stress for Cancer
Treatment........................................... 1121
Ushasri Chilakamarthi, Padma S. Singu, and Lingamallu Giribabu
58 Elevating the Reactive Oxygen Species in Cancer Cells
by Photodynamic Therapy.............................. 1145
Hillary Shah and Gnanasekar Munirathinam
59 Plasmonic Photothermal Therapy (PPTT) of Cancer.......... 1163
S. S. Verma and P. Bhatia
60 Role of ROS in Combined Radiation Effect in
Cancer Therapy...................................... 1183
Anshoo Gautam and Lipsy Goyal
xvi Contents

61 Application of Photodynamic Therapy for Treatment of
Oral Cancer..........................................1205
Mrinalini Sharma and Arpana Parihar
62 Advances in Photodynamic Protocols for Nonmelanoma
Skin Cancer..........................................1231
Michelle Barreto Requena, Ana Gabriela Salvio, and
Vanderlei Salvador Bagnato
63 Metallic Core-Shell Nanoparticles as Drug Delivery Vehicles
in Targeted Photodynamic Therapy of Cancer...............1245
Gauta Gold Matlou and Heidi Abrahamse
64 Recent Advancements in Nanomaterials for Photodynamic
Therapy of Cancers....................................1261
Asma Musfira Shabbirahmed, Mohanya Kumaravel, Prathap Somu,
Subhankar Paul, and Anjul Khadria
65 Photodynamic Therapy in Cancer........................1285
Pragya Pallavi, Agnishwar Girigoswami, Koyeli Girigoswami,
Surajit Hansda, and Rita Ghosh
66 Radiotherapy-Induced Augmentation of Cellular
Oxidative Stress.......................................1309
Rakesh Dhankhar and Kiran Dahiya
67 Photodynamic Therapy and ROS.........................1325
Rajesh Kumar, Deepika Dalal, Kirti Gupta, and Kiran Dahiya
Part IV Epigenetic Tools and Gene Therapy in ROS Management:
Implications in Cancer Progression..........................1337
68 Oxidative Stress-Mediated miRNA Regulation
in Cancer............................................1339
Debduti Datta and Suvendra N. Bhattacharyya
69 Reactive Oxygen Species: Induced Epigenetic Modification
in the Expression Pattern of Oncogenic Proteins.............1357
Loganayaki Periyasamy, Abhaya Krishnan, Mekhala Kumaravel
Palanichami, Ilangovan Ramachandran, R. Ileng Kumaran,
Jonathan Behlen, Jone A. Stanley, and Sridhar Muthusami
70 Targeting ROS-Induced Epigenetic Reprograming in
Cancer Stem Cells.....................................1373
Hari K. Koul, Sankaralingam Saikolappan, Binod Kumar, and
Sweaty Koul
Contents xvii

71 Therapeutic Implications of Long Non-coding RNA in the
Regulation of Lung Cancer..............................1387
Sukanya Ghosh, Anurima Samanta, Priyanka Prasad, and
Dona Sinha
72 Role of Histone Methylation in Cancer: Pathobiology and
Therapeutics......................................... 1411
Devipriya Nagarajan, Sunilgowda Sunnagatta Nagaraja, and
Shreya Baisakhiya
73 microRNAs-Mediated Regulation of Voltage Gated
Anion Channel 1: A Major Player in ROS Generation and
Cancer Progression....................................1429
Kuntal Dey and Soumasree De
74 Epigenetic Regulators of NRF2...........................1437
Shamee Bhattacharjee
75 Exosomal Non-coding RNAs.............................1457
Rajalakshmi Prakash, Kaumudi Pande, and Anbarasu Kannan
76 miRNA-Mediated Oxidative Stress Management
in Cancer............................................1491
Sourav Hom Choudhury, Syamantak Ghosh, and
Suvendra N. Bhattacharyya
77 A Critical Approach in the Analysis of lncRNA Characteristics
for Cancer Therapy.................................... 1511
Angshuman Bagchi and Gaurav Kumar Bhagat
78 Long Noncoding RNA Acting as Therapeutic Target for
Oxidative Stress-Induced Pancreatic Cancer................1525
Nilabja Sikdar, Akash Bararia, Ashmita Dutta, and Sudeep Banerjee
79 Short Non-coding RNAs: Emerging Molecular Players in
Therapeutics of ROS-Induced Cancer.....................1559
Sarmistha Adhikari, Sanchita Chandra, Anindita Goswami,
Subham Sarkar, and Paramita Mandal
80 Implications of NRF2 in Cancer Progression
and Therapeutics......................................1577
Madhunika Agrawal and Satyam Kumar Agrawal
81 Non-coding RNAs as Trojan Horse in Eliminating
ROS-Induced Cancer..................................1595
Siuli Shaw, Sartaj Khurana, Ranu Nayak, and Sudeep Bose
xviii Contents

82 Role of ROS-Mediated Epigenetic Alterations in the
Development of Solid Tumor.............................1609
Indranil Chattopadhyay
83 Role of Notch Signalling in Oxidative Stress and Stem
Cell Self-Renewal During Colitis and Colon Cancer..........1623
Qasim Andrabi and Satish Ramalingam
84 Oncogenic Virus-Induced Oxidative Stress and
Epigenetic Regulation: An Insight into Host
DNA Methylation.....................................1639
Isha Sengupta, Atanu Mondal, Amrita Sengupta, and Chandrima Das
85 Radiation-Induced Epigenetic Changes and Their Modulation
by Epidrugs..........................................1665
Teena Haritwal, Mrinalini Tiwari, and Paban Agrawala
86 Mucinous Colorectal Cancer Oxidative Stress and Therapeutic
MicroRNAs..........................................1681
Harsha Ganesan, M. K. Makalakshmi, Antara Banerjee,
Hong Zhang, Xiao-Feng Sun, and Surajit Pathak
87 Insights into the Oxidative Stress and microRNA-Based
Therapeutics in Colorectal Cancer........................1699
Sarubala Malayaperumal, Sushmitha Sriramulu, Alakesh Das,
Antara Banerjee, and Surajit Pathak
88 Oxidative Stress Associated Non-coding RNAs in
Pathogenesis of Urologic Cancers: Prognostic and
Therapeutic Importance................................1719
Abhishek Bardhan and Amlan Ghosh
89 Implications of Oxidative Stress and Epigenetic Drivers
in Ovarian Cancer Progression and Therapy................1739
Souvik Das, Sandip Ghosh, Pratiti Bhattacharjee, and Biswarup Basu
90 Noncoding RNA regulation and Oxidative Stress.............1763
Sayantani Bhowmik, Swagata Majumdar, and Soma Banerjee
91 MicroRNAs: The Master Regulators of the Breast
Cancer Tumor Microenvironment........................1787
Riley Feser, Reid Morgan Opperman, Sujit Maiti, and
Mousumi Majumder
92 Role of MicroRNA in ROS Modulation and Its
Implication in Lung Cancer and Therapeutics............... 1811
Ranita Roy, Santanu Paul, Kamal Dua, Gopal Chakrabarti, and
Amlan Das
Contents xix

Volume 3
Part V Stem Cells in Therapeutics of ROS-Induced Cancer . .....1835
93 Interplay of MicroRNAs and Reactive Oxygen Species in
Cancer Stem Cells: New Perspective in
Cancer Metastasis.....................................1837
Sweta Makwana and Chandi C. Mandal
94 Therapeutic Potential of Chemical Compounds in Targeting
Cancer Stem Cells.....................................1865
Pawan Kumar Raghav, Zoya Mann, and Sujata Mohanty
95 Functional Correlation Between ROS and Cancer Stem
Cells in Cancer Progression.............................1905
P. Vishnupriya, A. Aparna, and V. Vijaya Padma
96 Colon Cancer Stem Cells...............................1931
Lokesh Kumar Bhatt, Shivani Gokani, and Kalyani Barve
97 Therapeutic Modalities Regarding ROS in Leukemia and
Hematopoietic Stem/Progenitor Cell Perspective.............1947
Sujata Law and Sayantan Ghosh
98 Stemness and Stromal Niche: Targets in Oxidative
Stress–Induced Oral Cancer.............................1967
Subhashis Ghosh, Paromita Mitra, Kavya Vipparthi,
Priyanka Prasad, and Sandeep Singh
99 Targeting Signaling Pathways in Cancer Stem Cells for
Therapy of Cancer....................................1985
Rhea Conchita Gonsalves, Ekta Tripathi, Prashanthi Karyala,
Bilikere S. Dwarakanath, and Vivek Kumar
100 Cancer Stem Cell Oxidative Phosphorylation: Target for
Cancer Therapy......................................2003
Arvind Palani, Rifika Jain, and Gnanasekar Munirathinam
101 Targeting Oxidative Stress Specific NRF2 in Pancreatic
Cancer Stem Cells.....................................2021
Satish Sagar, Christabelle Rajesh, and Prakash Radhakrishnan
102 Redressal of the Molecular Mechanisms of Colon and Other
Cancer Stem Cell Energetics/Oxidative Stress for Possible
Translation..........................................2043
Shanooja Shanavas, Utsav Sen, P. Sudheer Shenoy, and
Bipasha Bose
xx Contents

103 Regenerative Medicines for ROS-Induced Cancers
Treatment...........................................2063
Dinesh Kumar, Maria Ishaque, and Pawan Kumar Raghav
104 Oxidative Stress-Related Mechanisms That Mediate
Chemoresistance in Cancer Stem Cells.....................2079
Geise Ellen Broto, Janaína Carla da Silva, Stefania Tagliari de
Oliveira, Matheus Ricardo Garbim, Mariane Okamoto Oliveira, and
Carolina Panis
105 Cancer Stem Cells in Therapy Resistance of
Colorectal Cancer.....................................2101
Ying Yang, Wen-Jian Meng, and Zi-Qiang Wang
106 Role of Stem Cells and Reactive Oxygen Species
in Cancer............................................ 2117
Devaraj Ezhilarasan, Perumal Elumalai, Balakrishnan Anandan, and
Anbalagan Muralidharan
107 Therapeutic Strategies Targeting Wnt/β-Catenin Signaling
Pathway in Stem Cells for ROS-Induced
Cancer Progression....................................2133
M. Samatha Jain, M. K. Makalakshmi, Dikshita Deka,
Surajit Pathak, and Antara Banerjee
108 Delineating the Role of PI3K Signaling Pathway in the
Stem Cell Therapeutics of ROS-Induced Carcinomas.........2153
Bhuvanadas Sreeshma, Anjali P. Patni, Rajib Dhar, and Arikketh Devi
109 Therapeutic Strategies for ROS-Dependent Tumor
Angiogenesis Using Vascular Stem Cells....................2179
Sambhavi Bhagavatheeswaran and Anandan Balakrishnan
110 Mesenchymal Stem Cell-Mediated Suicide
Gene Therapy........................................2191
Megala Jayaraman, Parijat Dutta, Khyati Arora, Diveyaa Sivakumar,
Jayesh Telang, Hanumanth Rao Balaji Raghavendran, and
Kayalvizhi Nagarajan
111 Biopolymer-Based Nanocarriers for Stem Cells or
Stem Cell Differentiating Agents and Their
Therapeutic Significance................................2207
Shoba Narayan
Contents xxi

112 Reactive Oxygen Species and Cancer Stem Cells: Molecular
Interactions and Their Implications in Cancer...............2227
Gautham Chengizkhan, Kavitha Sukumar, Ajaikumar B.
Kunnumakkara, Lurdes Queimado, Arasambattu Kannan Munirajan,
Ravi Sankar Bhaskaran, R. Ileng Kumaran, and
Ilangovan Ramachandran
113 The Complex Interplay Between JAK-STAT Pathway and
ROS in Regulating Stem Cells During Inflammation
and Cancer..........................................2269
Sivaramakrishnan Venkatabalasubramanian
114 Emerging Metabolic Regulation of Redox Status in Cancer
Stem Cells Progression and Metastasis.....................2281
Darshan Mehta and Sanjeev K. Waghmare
115 Exosomes Regulate ROS in Cancer Stem Cells..............2297
Raja Natesan Sella
116 Photodynamic Oxidative Stress Targets Cancer as Well
as Cancer Stem Cells...................................2315
Anine Crous, Sajan George, and Heidi Abrahamse
117 Adipose-Derived Stem Cells as Photodynamic Therapeutic
Carriers for Treatment of Glioblastoma Exploiting Reactive
Oxygen Species.......................................2335
Madeleen Jansen van Rensburg, Daniella Da Silva, Anine Crous, and
Heidi Abrahamse
118 Targeting the Metabolism in Cancer Cells for
Cancer Therapy.......................................2357
Manju Mohan, Shabana Thabassum Mohammed Rafi, Sridhar
Muthusami, Satish Ramalingam, Yuvaraj Sambandam, Karuppaiyah
Selvendiran, Ilangovan Ramachandran, and R. Ileng Kumaran
119 Cancer Stem Cells: Reactive Oxygen Species-Induced
Drug Resistance in Cancer..............................2381
Praveen Rajendran, Selvaraj Jayaraman, Ganesh Munuswamy-
Ramanujam, Rajappan Chandra Satish Kumar, Balamurugan
Ramachandran, Yuvaraj Sambandam, Dhanavathy
Gnanasampanthapandian, and Kanagaraj Palaniyandi
xxii Contents

120 Reactive Oxygen Species in Oral Squamous Cell Carcinoma
Progression and Importance of Stem Cells in
Cancer Therapeutics...................................2403
Reji Manjunathan, Selvaraj Jayaraman, Ramya S., R. Ileng
Kumaran, Parthasarathy Chandrakesan, Ponnulakshmi Rajagopal,
and Yuvaraj Sambandam
121 Regulation of ROS in Skin Stem Cells for
Cancer Therapeutics...................................2427
S. Najeeb, Surya Suresh, S. S. Raga, T. M. Binumon, and
Sreejith Parameswara Panicker
122 Modulation of Reactive Oxygen Species and Cancer
Stemness by Catechins.................................2451
T. S. Gopenath, S. Logesh, Deepthi, and B. M. Kanthesh
123 Mesenchymal Stem Cells................................2465
Ragini Yeeravalli and Amitava Das
124 Induction of Oxidative Stress: A Promising Approach in
Female Gynecological Cancer Therapeutic Arsenal...........2489
Cornelia Amalinei, Raluca Anca Balan, and Ludmila Lozneanu
125 Iron Vulnerability of Cancer Stem Cells....................2509
Mushtaq Ahmad Nengroo, Abhipsa Sinha, and Dipak Datta
126 Targeting Epithelial-to-Mesenchymal Transition for
Breast Cancer Stem Cells Therapeutics....................2539
Shruthi Suthakaran, Digvijay Singh, Rohit K. Deshmukh, and
Amitava Das
127 ROS Signaling in Brain Tumor...........................2565
Debashmita Sarkar and Shilpee Dutt
128 Current Insights to Therapeutic Targets of ROS-Induced
Gastric Cancer Stem Cells..............................2585
Amrita Nandan, Pawan Kumar Raghav, Avani Srivastava,
Santosh Kumar Tiwari, Ajay Kumar Shukla, and Vishwas Sharma
129 Clinical Approaches in Targeting ROS-Induced Cancer.......2599
Anugya Sengar, Manisha Sengar, Zoya Mann, and
Pawan Kumar Raghav
130 ROS-Induced Cancers..................................2615
Sibani Sarkar, Malini Basu, and Mrinal K. Ghosh
Contents xxiii

131 An Insight into Targeted Therapy for Ovarian Cancer........2635
Abhishek Chatterjee, Vineet Kumar Mishra, Susmita Saha, and
Snehasikta Swarnakar
Volume 4
Part VI Nanotechnology-Based Therapeutics of
ROS-Induced Cancer . .....................................2657
132 The Multifaceted Function of Nanoparticles in Modulating
Oxidative Stress in Cancer Therapy.......................2659
Shima Masoudi Asil and Mahesh Narayan
133 Selenium Nanoparticle in the Management of Oxidative
Stress During Cancer Chemotherapy......................2677
Ugir Hossain Sk, Debapriya RoyMahapatra, and Sudin Bhattacharya
134 Emerging Role of Redox-Active Nanoceria in Cancer
Therapeutics via Oxidative Stress.........................2709
Neelam Thakur, Joydeep Das, and Parames C. Sil
135 Nanotechnology in ROS-induced Cancer Therapy............2733
Deepika Singh and Ankit Sahoo
136 Nanotechnology-Based ROS-Triggered Therapeutic
Strategies in Multiple Cancer............................2753
Sonali Mohanty and Subhankar Paul
137 Nanotechnology in Cancer Diagnosis and Therapy...........2779
Minakshi Prasad, Lukumoni Buragohain, Mayukh Ghosh, and
Rajesh Kumar
138 Biogenic Nanomaterials Derived ROS for
Cancer Therapy......................................2803
Abu Baker and Mohd Sajid Khan
139 Emerging Nano-selenium: An insight to Its Current Status
and Potentials in ROS-Induced Cancer
Prevention and Therapy................................2817
Tanmoy Rana
140 Oxidative Stress-Dependent Anticancer Potentiality of
Nanotherapeutic Zinc Oxide.............................2829
Noyel Ghosh, Sharmistha Chatterjee, Mousumi Kundu, and
Parames C. Sil
141 Polymeric Nanoparticle-Encapsulated Curcumin:
A Preventive Strategy in ROS-Induced Carcinogenesis........2851
Tapasi Rana
xxiv Contents

142 EPR-Selective Biodegradable Polymer-Based
Nanoparticles for Modulating ROS in the Management
of Cervical Cancer....................................2863
Sujit Kumar Debnath, Barkha Singh, Nidhi Agrawal, and
Rohit Srivastava
143 Graphene-Based Nanomaterials for ROS-Mediated Cancer
Therapeutics.........................................2891
Shagufta Haque, Sanchita Tripathy, and Chitta Ranjan Patra
144 Bio-inspired Protein-Based Nanoparticles in
Cancer Therapy......................................2917
Pradakshina Sharma, Mohd. Rahil Hasan, and Jagriti Narang
145 ROS-Responsive Bioconjugate Nanoparticles in
Cancer Treatment.....................................2941
Fatemeh Bahadori, Ali Asram Sagiroglu, Burak Celik, and
Ahmed Serdar Kozanoglu
146 Harnessing Microenvironment Variation for
Nanotechnology-Based Therapeutics of
ROS-Induced Cancer..................................2959
Vishakha Chaudhary, Anju Anju, Deepika Sharma,
Shubhra Chaturvedi, and Anil K. Mishra
147 Experimental Animal Models to Evaluate the Therapeutic
Efficacy of Nanoformulations Against Cancer...............2971
Shoba Narayan
148 Nanotechnologies in Oncology...........................2993
Hanieh Montaseri and Heidi Abrahamse
149 A Detailed Overview of ROS-Modulating Approaches
in Cancer Treatment...................................3017
Prathap Somu, Sonali Mohanty, and Subhankar Paul
150 Nanotechnology-Based Therapeutics in
ROS-Induced Cancer..................................3039
Hadgu Mendefro Berehu, S. Anupriya, and Srinivas Patnaik
151 Recent Developments in ROS-Based Nanotherapeutic
Modalities in Preclinical Cancer Treatment.................3059
Neha Suyog Potnis, Akbar Ali, and Suchetan Pal
152 Free Radical Chemistry of Carotenoids and Oxidative
Stress Physiology of Cancer.............................3077
Rangaswamy Lakshminarayana and Bishwajit Paul
Contents xxv

153 Targeting Redox Homeostasis in Tumor Cells
Using Nanoparticles...................................3099
Atul Bharde
154 In Silico Analysis of Oxidative Stress Gene Expression
Profile and Biomarker Detection......................... 3117
Kazi Nasrin Sultana and Sandeep Kumar Srivastava
155 Nanomedicines for Tumor-Associated Macrophages..........3133
Abhishek Teli, Prajakta Gaikwad, Sakshi Chakave, Akshay Kane,
and Tuli Dey
156 Synthetic Migrastatic: A New Class of Anticancer Drug.......3157
Sukanya Gayan, Saurav Doshi, and Tuli Dey
157 Targeting Reactive Oxygen Species (ROS) for
Cancer Therapy......................................3181
Hari Mohan, Vandna, Subodh Soni, and Shafiq Syed
Part VII Bioinformatics and System Biology Approach for
Targeting ROS in Cancer Therapy...........................3197
158 Elucidation of Possible Role of Heat Shock Protein as
Potent Therapeutic Agent in ROS-Mediated Cancer
and Its Assessment Through Computational
Biology Methods......................................3199
Sangeeta Mitra, Angshuman Bagchi, and Rakhi Dasgupta
159 An Overview of In Silico Drug Discovery with Emphasis
on Cancer...........................................3215
Sima Biswas and Angshuman Bagchi
160 Application of Bioinformatics Databases in the Study of
Oxidative Stress Related Cancers.........................3229
Angshuman Bagchi and Gaurav Kumar Bhagat
161 Emerging Scope of Computer-Aided Drug Design in
Targeting ROS in Cancer Therapy........................3241
Deepika Sharma, Shubhra Chaturvedi, Vishakha Chaudhary,
Ankur Kaul, and Anil K. Mishra
162 ROS Modulatory Role of HDAC Inhibitors in
Cancer Cells.........................................3259
Janaki Ramaiah Mekala, PrasannaSrinivasan Ramalingam,
Nageswara Rao Moparthi, and Vijay Kumar Kutala
163 Therapeutic Potential of Modulating Oxidative DNA
Damage in Breast Cancer...............................3287
Shaik Mohammad Naushad and Vijay Kumar Kutala
xxvi Contents

164 Systems Biology and Bioinformatics Approaches Unraveling
the Therapeutic Potential of Novel Drugs in Counteracting
the Oxidative Stress Adaptation in Prostate Cancer..........3295
Shaik Mohammad Naushad and Vijay Kumar Kutala
Volume 5
Part VIII Other Aspects of Therapeutics of ROS-Induced
Cancer.................................................. 3305
165 Some Aspects of Oxidative Stress–Induced Prostate
Cancer Therapy......................................3307
Md Nur Alam, Tapati Chakraborti, Priyanka Ghosh,
Pijush Kanti Pramanik, Pujayita Devgupta, and Sajal Chakraborti
166 Reactive Oxygen Species in Glioma.......................3329
Ravindra Pramod Deshpande and Phanithi Prakash Babu
167 Genetic Factors Contributing ROS-Driven Chemotherapy
and Drug Resistance in Cancer...........................3345
Amit K. Maiti
168 Metabolic Oxidative Stress..............................3363
Manika Pal Bhadra, Ganesh Kumar Raut, and Moumita Chakrabarti
169 A CRISPR-Cas9-Based Therapeutics in Oxidative
Stress-Induced Cancer.................................3383
Nivya Vijayan, V. P. Venkatiesh, Vani Vijay, Anbarasu Kannan,
Baskaran Vallikannan, and Madan Kumar Perumal
170 Molecular Mechanism of Oxidative Stress in Cancer
and Its Therapeutics...................................3401
Ashif Iqubal and Syed Ehtaishamul Haque
171 Pro-apoptotic Effects of Dietary Flavonoids in Oxidative
Stress-Induced Cancer.................................3417
Vani Vijay, Nivya Vijayan, V. P. Venkatiesh, Baskaran Vallikannan,
and Madan Kumar Perumal
172 Redox Signaling.......................................3435
Surajit Bhattacharjee, Suman Paul, and Chandan RayBarman
173 Mechanistic and Therapeutic Crosstalk of Lipid Peroxidation
in Oxidative Stress and Breast Cancer.....................3457
Manjari Singh and Gaurav Kaithwas
Contents xxvii

174 Therapeutic Implication of Oxidative Stress Regulators
in Drug-Resistant Cancers..............................3477
Qingbin Cui, Jing-Quan Wang, Dong-Hua Yang, and
Zhe-Sheng Chen
175 Y-Box-Binding Protein-1................................3497
Vinoth Prasanna Gunasekaran, Sudarshan Naidu, and Kumari Nishi
176 Microbe-Induced Oxidative Stress in Cancer
Development and Efficacy of Probiotics as Therapeutics
in Preventing Its Onset and Progression....................3513
Pinaki Biswas, Suchetana Pal, Moubonny Das, and Somasri Dam
177 Role of Forkhead Box Proteins in Regulating
Epithelial-Mesenchymal Transition in Breast Cancer.........3543
Syamala Soumyakrishnan, M. Sreepriya, and G. Sudhandiran
178 Targeting Mitochondria as a Novel Disease-Modifying
Therapeutic Strategy in Cancer..........................3563
Arvinder K. Kapur, Sejal Sharma, and Manish S. Patankar
179 Pathogenesis of Oxidative Stress in Lung Cancer and Its
Therapeutic Aspects...................................3589
V. Ramakrishnan and M. Vajagathali
180 Modulators of ROS/NF-κB Signaling in Cancer Therapy...... 3611
Maria Voura, Eleni Sflakidou, and Vasiliki Sarli
181 Targeting Tumors Through Enhancers of
Oxidative Stress.......................................3629
Gurjit Kaur Bhatti, Paras Pahwa, Anshika Gupta, Inderpal Singh
Sidhu, Uma Shanker Navik, P. Hemachandra Reddy, and
Jasvinder Singh Bhatti
182 Proteomics and Metabolomics in Cancer
Diagnosis and Therapy.................................3649
Minakshi Prasad, Somesh Banerjee, Suman, Rajesh Kumar,
Lukumoni Buragohain, and Mayukh Ghosh
183 Oxidative Stress-Induced Autophagy......................3679
Jyoti Sethi and Utkarsh Sethi
184 Antioxidant Supplementation............................3695
Deepika Dalal, Ashish Kumar Malik, and Kiran Dahiya
185 Matrix Metalloproteinases (MMPs) in Cancer
Immunotherapy.......................................3707
Pavan Kumar Yadav, Mayukh Ghosh, and Meena Kataria
xxviii Contents

186 Pathogens and Cancer..................................3733
Vishal Khatri, Gnanasekar Munirathinam, and
Ramaswamy Kalyanasundaram
187 Susceptibility of PolymorphicGSTas a Risk Factor
in Oxidative Stress-Induced Cancer Development............3757
S. Santhi Priya and K. Kumar Ebenezar
188 Present Status of the Therapeutic Approaches to Treat Uveal
Melanoma...........................................3773
Amritlal Mandal, Mathews Valuparampil Varghese, and Joel James
189 Reactive Oxygen Species–Induced Cancer Cell Death:
A Therapeutic Approach................................3793
Alexander Chota, Blassan P. George, and Heidi Abrahamse
190 Oxidative Stress in Cancer: Therapeutic Implications
of Small-Molecule Kinase Inhibitors.......................3809
Shailender S. Chauhan, Neha Singh, Noel A. Warfel, and
Sathish Kumar Reddy Padi
191 Novel Developmental Therapeutics Targeting Human
Oral Squamous Cell Carcinoma Through Reactive
Oxygen Species-Mediated Apoptosis.......................3827
T. Jesse Joel, Jobin John, Levin Anbu Gomez, and Ritu Shepherd
192 The Link Between Circadian Rhythm and
ROS-Induced Cancer..................................3839
Ahamed Basha Abdul Bari and Prince Johnson Samuel
193 Targeting the Antioxidant Enzymes for the Treatment of
Reactive Oxygen Species (ROS)-Induced Cancer.............3857
Sneha Krishnamoorthy, Kokelavani Nampalli Babu, Loganayaki
Periyasamy, Jone A. Stanley, Ilangovan Ramachandran,
R. Ileng Kumaran, and Sridhar Muthusami
194 A General Overview on Causes, Risk Factors, Diagnosis,
Treatment, and Role of Oxidative Stress Biomarkers
in Colorectal Cancer...................................3877
Sushmitha Sriramulu, Sarubala Malayaperumal, Dikshita Deka,
Antara Banerjee, and Surajit Pathak
195 Oxidative Stress in the Pathogenesis of Ovarian Cancer.......3897
S. Winkins Santosh, Allen J. Freddy, and Daphne Winkins
196 Adipose-Derived Stem Cells.............................3909
Adriana Grigoras and Cornelia Amalinei
Contents xxix

197 Translational Reprogramming of mRNA in Oxidative
Stress and Cancer.....................................3925
Alina Chakraborty
198 Regulation of Cellular Stress in the Light of mRNA Alternative
Polyadenylation.......................................3941
Srimoyee Mukherjee
199 Impact of Chemotherapeutic Drugs Towards Oxidative
Stress and Associated Multi-organ
Physiological Responses................................3961
Sreemoyee Chakraborti, Adele Stewart, and Biswanath Maity
200 The Role of Endothelin Axis and Reactive Oxygen Species
in Future Therapies of Pancreatic Cancer..................3987
Jaganmay Sarkar and Hiranmoy Das
201 Targeting the Transcription Factors of ROS Tumorigenic
Pathways as a Therapeutic Strategy in Cancer..............4003
Kannappan Sriramajayam, Ravindran Caspa Gokulan, and
Jayaraman Tharmalingam
202 Oxidative Stress in the Pathogenesis of Cervical Cancer.......4023
S. Winkins Santosh, Allen J. Freddy, and Daphne Winkins
203 Antioxidants in Oxidative Stress and Biocatalysts: Their
Correlation with Cancer................................4031
Ratnakar R. Chitte and Sushma Chaphalkar
204 Biofluid Markers Unveiling Cancer Diagnosis and Prognosis:
With Special Reference to Oxidative Stress.................4041
Sonaa Elango, Karpagam Veerappan, and Usha Subbiah
Index.................................................... 4055
xxx Contents

About the Editor
Dr. Sajal Chakrabortiis a Professor of Biochemistry
at the University of Kalyani, West Bengal, India.
His research covers the role of oxidant-mediated
signaling in the pathogenesis of a variety of diseases.
Dr. Chakraborti did is PhD from Calcutta University
(1982) and DSc from Kalyani University (2004). He
also did postdoctoral research at the Johns Hopkins
University, Baltimore; University of Utah Health Sci-
ences Center, Salt Lake City; and New York Medical
College, New York, as a Fulbright Fellow (1987–1990).
He received Department of Biotechnology (Govt. of
India) Senior Overseas Research Award for his research
at the University of Florida, Gainesville (1998–1999).
He has been engaged in teaching and research in Bio-
chemistry for the past 40 years. He has published over
120 original research papers, 22 book chapters, and
15 review articles. He also edited 12 books published
by Springer.
xxxi

Contributors
Mohamed A. AdilSchool of Allied Health Sciences, Meenakshi Academy of
Higher Education and Research (MAHER), Chennai, India
Eman R. Abd ElhaliemPhysiology Division, Zoology Department, Faculty of
Science, Beni-Suef University, Beni-Suef, Egypt
Ahamed Basha Abdul BariDepartment of Physiology, Chettinad Hospital and
Research Institute, Chettinad Academy of Research and Education, Chennai
(Chengalpattu District), Tamil Nadu, India
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University
of Johannesburg, Johannesburg, South Africa
Sarmistha AdhikariBiomedical Genetics Laboratory, Department of Zoology,
The University of Burdwan, Burdwan, West Bengal, India
Madhunika AgrawalUniversity Institute of Pharmaceutical Sciences, Panjab
University, Chandigarh, India
Cellsinvitro Biotech Research Solutions, SAS Nagar (Mohali), Punjab, India
Nidhi AgrawalSchool of Biotechnology and Bioinformatics, D Y Patil Deemed to
be University, Navi Mumbai, India
Satyam Kumar AgrawalCellsinvitro Biotech Research Solutions, SAS Nagar
(Mohali), Punjab, India
Chitkara University Research and Innovation Network, Chitkara University,
Rajpura, Punjab, India
Paban AgrawalaRadiation Genetics and Epigenetics Department, Institute of
Nuclear Medicine and Allied Sciences, Delhi, India
Noha A. AhmedPhysiology Division, Zoology Department, Faculty of Science,
Beni-Suef University, Beni-Suef, Egypt
Osama M. AhmedPhysiology Division, Zoology Department, Faculty of Science,
Beni-Suef University, Beni-Suef, Egypt
Md Nur AlamDepartment of Life Sciences, Presidency University, Kolkata, India
xxxiii

Akbar AliIndian Institute of Technology Bhilai, Raipur, India
Cornelia AmalineiFaculty of Medicine, Department of Morphofunctional
Sciences I,“Grigore T. Popa”University of Medicine and Pharmacy, Iasi, Romania
Balakrishnan AnandanDepartment of Genetics, Dr. ALM Post Graduate institute
Basic Medical sciences, University of Madras, Chennai, TN, India
Suresh Kumar AnandasadagopanDepartment of Biochemistry and Biotechnol-
ogy Lab, CSIR-Central Leather Research Institute, Chennai, India
Qasim AndrabiDepartment of Genetic Engineering, School of Bio-Engineering,
SRM Institute of Science and Technology, Kattankulathur, Kanchipuram, Tamil
Nadu, India
Anju AnjuDivision of Cyclotron and Radiopharmaceutical Sciences, INMAS,
DRDO, Timarpur, Delhi, India
AnkurDepartment of Zoology, Research Scholar, Chaudhary Bansi lal University,
Bhiwani, Haryana, India
Pushparaj AnnaduraiPeriyar EVR College (Autonomous), Tiruchirappalli, India
Aasia AnsariApplied Biology Division, CSIR-Indian Institute of Chemical Tech-
nology, Hyderabad, India
Academy of Scientific and Innovation Research (AcSIR), CSIR-HRDC campus,
Ghaziabad, India
S. AnupriyaDisease Biology Laboratory, School of Biotechnology, KIIT Deemed
to be University, Bhubaneswar, Odisha, India
A. AparnaTranslational Research Laboratory, Department of Biotechnology,
Bharathiar University, Coimbatore, Tamil Nadu, India
Prisilla ArockiasamyDepartment of Biotechnology and Bioinformatics, Bishop
Heber College, Tiruchirappalli, Tamil Nadu, India
Khyati AroraDepartment of Genetic Engineering, Faculty of Engineering and
Technology, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India
Somasundaram Arumugam Department of Pharmacology & Toxicology,
National Institute of Pharmaceutical Education and Research (NIPER), Kolkata,
West Bengal, India
Harini ArumugasamyFaculty of Allied Health Sciences, Dr. M.G.R Educational
and Research Institute, Chennai, Tamil Nadu, India
Shima Masoudi AsilDepartment of Environmental Science & Engineering, The
University of Texas, El Paso, TX, USA
K. S. AswathiDepartment of Pharmaceutical Analysis, St. James’College of
Pharmaceutical Sciences (SJCOPS), Chalakudy, Kerala, India
xxxiv Contributors

Iriny M. AyoubDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams
University, Cairo, Egypt
Juberiya M. AzeezCancer Research Program, Rajiv Gandhi Centre for Biotech-
nology, Thiruvananthapuram, India
Kokelavani Nampalli BabuDepartment of Biochemistry, Karpagam Academy of
Higher Education, Coimbatore, Tamil Nadu, India
Phanithi Prakash BabuDepartment of Biotechnology and Bioinformatics, School
of Life Sciences, University of Hyderabad, Hyderabad, India
Angshuman BagchiDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Vanderlei Salvador BagnatoSao Carlos Institute of Physics, University of Sao
Paulo (USP), Sao Carlos, SP, Brazil
Hagler Institute for Advanced Studies, Texas A&M University, College Station
Texas, TX, USA
Fatemeh BahadoriDepartment of Pharmaceutical Biotechnology, Faculty of
Pharmacy, Bezmialem Vakif University, Istanbul, Turkey
Shreya BaisakhiyaRadiation Biology Lab, AKS-II, School of Chemical and
Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India
Abu BakerNanomedicine and Nanotechnology Lab, Department of Biosciences,
Integral University, Lucknow, Uttar Pradesh, India
Anandan BalakrishnanDepartment of Genetics, Dr. ALM PG IBMS, University
of Madras, Chennai, Tamilnadu, India
Raluca Anca BalanFaculty of Medicine, Department of Morphofunctional Sci-
ences,“Grigore T. Popa”University of Medicine and Pharmacy Iasi, Ias‚i, Romania
Antara BanerjeeDepartment of Medical Biotechnology, Faculty of Allied Health
Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hos-
pital and Research Institute (CHRI), Chennai, Tamil Nadu, India
Rajkumar BanerjeeApplied Biology Division, CSIR-Indian Institute of Chemical
Technology, Hyderabad, India
Academy of Scientific and Innovation Research (AcSIR), CSIR-HRDC campus,
Ghaziabad, India
Soma BanerjeeCenter for Liver Research, School of Digestive and Liver Diseases,
Institute of Post Graduate Medical Education and Research, Kolkata, India
Somesh BanerjeeDepartment of Veterinary Microbiology, Immunology Section,
Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India
Sudeep BanerjeeDepartment of Gastrointestinal Surgery, Tata Medical Center,
Kolkata, West Bengal, India
Contributors xxxv

Akash BarariaHuman Genetics Unit, Indian Statistical Institute, Kolkata, West
Bengal, India
Abhishek BardhanGenetics of Non-communicable Diseases, Department of Life
Sciences, Presidency University, Kolkata, India
Kalyani BarveDepartment of Pharmacology, SPP School of Pharmacy & Tech-
nology Management, NMIMS University, Vile Parle (West), Mumbai, India
Biswarup BasuDepartment of Neuroendocrinology & Experimental Hematology,
Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
Malini BasuDepartment of Microbiology, Dhruba Chand Halder College, Dakshin
Barasat, India
Jonathan BehlenCollege of Veterinary Medicine and Biomedical Sciences, Texas
A&M University, College Station, TX, USA
Hadgu Mendefro BerehuDisease Biology Laboratory, School of Biotechnology,
KIIT Deemed to be University, Bhubaneswar, Odisha, India
Daniel P. BezerraGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-
FIOCRUZ/BA), Salvador, BA, Brazil
Manika Pal BhadraApplied Biology, CSIR-Indian Institute of Chemical Tech-
nology, Hyderabad, Telangana, India
Academy of Scientific and Innovative Research (AcSIR), Training and Development
Complex, CSIR-Human Resource Development Centre, Ghaziabad, India
Gaurav Kumar BhagatDepartment of Biochemistry and Biophysics, University
of Kalyani, Kalyani, West Bengal, India
Sambhavi BhagavatheeswaranDepartment of Genetics, Dr. ALM PG IBMS,
University of Madras, Chennai, Tamilnadu, India
Atul BhardeDepartment of Microbiology, Savitribai Phule Pune University
(Formerly University of Pune), Pune, India
Ravi Sankar BhaskaranDepartment of Endocrinology, Dr. ALM PG Institute of
Basic Medical Sciences, University of Madras, Taramani Campus, Chennai, Tamil
Nadu, India
P. BhatiaDepartment of Physics, Sant Longowal Institute of Engineering and
Technology, Sangrur, Punjab, India
Lokesh Kumar BhattDepartment of Pharmacology, SVKM’s Dr. Bhanuben
Nanavati College of Pharmacy, Vile Parle (West), Mumbai, India
Pratiti BhattacharjeeDepartment of Neuroendocrinology & Experimental Hema-
tology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
xxxvi Contributors

Shamee BhattacharjeeDepartment of Zoology, West Bengal State University,
Kolkata, India
Surajit BhattacharjeeDepartment of Molecular Biology & Bioinformatics,
Tripura University (A Central University), Agartala, Tripura, India
Sanjib BhattacharyaWest Bengal Medical Services Corporation Ltd., Kolkata,
West Bengal, India
Sudin BhattacharyaChittaranjan National Cancer Institute, Kolkata, West Bengal,
India
Suvendra N. BhattacharyyaRNA Biology Research Laboratory, Molecular Genet-
ics Division, CSIR-Indian Institute of Chemical Biology, Kolkata, West Bengal, India
Gurjit Kaur BhattiDepartment of Medical Lab Technology, University Institute
of Applied Health Sciences, Chandigarh University, Mohali, Punjab, India
Jasvinder Singh BhattiDepartment of Biosciences, Sri Guru Gobind Singh
College, Chandigarh, India
Department of Human Genetics and Molecular Medicine, School of Health
Sciences, Central University of Punjab, Bathinda, India
Sayantani BhowmikCenter for Liver Research, School of Digestive and Liver
Diseases, Institute of Post Graduate Medical Education and Research, Kolkata, India
Anjali BijalwanDepartment of Pharmacology, Central University of Punjab,
Bathinda, India
Ponnamparambil Purushothaman BinithaRoyal Dental College, Palakkad
District, Kerala, India
T. M. BinumonDepartment of Zoology, Advanced Centre for Regenerative Med-
icine and Stem cell in Cutaneous Research (AcREM-Stem), University of Kerala,
Thiruvananthapuram, Kerala, India
Pinaki BiswasDepartment of Microbiology, The University of Burdwan,
Burdwan, India
Sima BiswasDepartment of Biochemistry and Biophysics, University of Kalyani,
Kalyani, West Bengal, India
Soumi BiswasDepartment of Biochemistry and Biophysics, University of Kalyani,
Kalyani, West Bengal, India
Khalida BlochDepartment of Microbiology, School of Science, RK University,
Rajkot, Gujarat, India
Bipasha BoseStem Cells and Regenerative Medicine Centre, Yenepoya Research
Centre, Yenepoya (Deemed to be University), Mangalore, Karnataka, India
Contributors xxxvii

Sudeep BoseAmity Institute of Biotechnology, Amity University, Noida,
Uttar Pradesh, India
Amity Institute of Molecular Medicine and Stem Cell Research, Amity University,
Noida, Uttar Pradesh, India
Gartrell C. BowlingSchool of Medicine, Uniformed Services University of Health
Sciences (USUHS), Bethesda, MD, USA
Geise Ellen BrotoLaboratory of Tumor Biology, Post-Graduation Program in
Applied Health Sciences, State University of West Paraná, Unioeste, Francisco
Beltrão, PR, Brazil
Post-Graduation Program in Clinical and Laboratory Physiopathology, State Uni-
versity of Londrina, Londrina, PR, Brazil
Lukumoni BuragohainDepartment of Animal Biotechnology, College of
Veterinary Science, Assam Agricultural University, Guwahati, Assam, India
Ravindran Caspa GokulanDepartment of Surgery, Miller School of Medicine,
University of Miami, Miami, FL, USA
Burak CelikDepartment of Pharmaceutical Technology, Faculty of Pharmacy,
Bezmialem Vakif University, Istanbul, Turkey
Sakshi ChakaveInstitute of Bioinformatics and Biotechnology, Savitribai Phule
Pune University, Pune, Maharashtra, India
Gopal ChakrabartiDepartment of Biotechnology and Dr. B.C. Guha Centre for
Genetic Engineering and Biotechnology, University of Calcutta, Kolkata, West
Bengal, India
Moumita ChakrabartiApplied Biology, CSIR-Indian Institute of Chemical Tech-
nology, Hyderabad, Telangana, India
Academy of Scientific and Innovative Research (AcSIR), Training and Development
Complex, CSIR-Human Resource Development Centre, Ghaziabad, India
Sajal ChakrabortiDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Sreemoyee ChakrabortiCentre of Biomedical Research, Sanjay Gandhi
Post-Graduate Institute of Medical Sciences campus, Lucknow, UP, India
Tapati ChakrabortiDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Alina ChakrabortyInstitut Curie, PSL Research University, CNRS UMR3348,
INSERM U1278, Orsay, France
Université Paris Sud, Université Paris-Saclay, CNRS UMR3348, INSERM U1278,
Orsay, France
Equipe Labellisée Ligue Nationale Contre le Cancer, Orsay, France
xxxviii Contributors

Siva Reddy ChallaDepartment of Cancer Biology and Pharmacology, University
of Illinois College of Medicine, Peoria, IL, USA
Sanchita ChandraBiomedical Genetics Laboratory, Department of Zoology, The
University of Burdwan, Burdwan, West Bengal, India
Karthikeyan ChandraboseSchool of Allied Health Sciences, Meenakshi Acad-
emy of Higher Education and Research (MAHER), Bhopal, India
Parthasarathy ChandrakesanDepartment of Medicine & OU Cancer Institute,
University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Pithi ChanvorachoteDepartment of Pharmacology and Physiology, Center
of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical
Sciences, Chulalongkorn University, Bangkok, Thailand
Sushma ChaphalkarS. P. College, Jejuri, India
Abhishek ChatterjeeInfectious Diseases and Immunology Division, CSIR-Indian
Institute of Chemical Biology, Kolkata, West Bengal, India
Sharmistha ChatterjeeDivision of Molecular Medicine, Bose Institute, Kolkata,
India
Subhajit ChatterjeeCancer Biology Division, School of Biotechnology, Kalinga
Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar,
Odisha, India
Indranil ChattopadhyayDepartment of Life Sciences, Central University of
Tamil Nadu, Thiruvarur, Tamilnadu, India
Pragya ChaturvediDepartment of Human Genetics and Molecular Medicine,
Central University of Punjab, Bathinda, India
Shubhra ChaturvediDivision of Cyclotron and Radiopharmaceutical Sciences
(DCRS), Institute of Nuclear Medicine and Allied Sciences (INMAS)-DRDO,
Delhi, India
Vishakha ChaudharyKirori Mal College, University of Delhi, North Campus,
University Enclave, Delhi, India
Division of Cyclotron and Radiopharmaceutical Sciences (DCRS), Institute of
Nuclear Medicine and Allied Sciences (INMAS)-DRDO, Delhi, India
Shailender S. ChauhanCellular and Molecular Medicine, University of Arizona
Cancer Center, The University of Arizona, Tucson, AZ, USA
Rahul CheckerRadiation Biology & Health Sciences Division, Bio-science
Group, Bhabha Atomic Research Centre, Mumbai, India
Homi Bhabha National Institute, Mumbai, India
Dinesh Kumar ChellappanDepartment of Life Sciences, International Medical
University, KualaLumpur, Malaysia
Contributors xxxix

Zhe-Sheng ChenDepartment of Pharmaceutical Sciences, College of Pharmacy
and Health Sciences, St. John’s University, Queens, NY, USA
Gautham ChengizkhanDepartment of Endocrinology, Dr. ALM PG Institute of
Basic Medical Sciences, University of Madras, Taramani Campus, Chennai, Tamil
Nadu, India
Ushasri ChilakamarthiPolymers and functional materials Division, CSIR-Indian
Institute of Chemical Technology, Hyderabad, Telangana, India
Ratnakar R. ChitteMicrobiology Department, Vanita Vishram Women Univer-
sity, Surat, India
Alexander ChotaLaser Research Centre, Faculty of Health Sciences, University
of Johannesburg, Johannesburg, South Africa
Preedakorn ChunhachaDepartment of Biochemistry and Microbiology, Faculty
of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceu-
tical Sciences, Chulalongkorn University, Bangkok, Thailand
Oana CioancaDepartment of Pharmacognosy-Phytotherapy,“Grigore T. Popa”
University of Medicine and Pharmacy, Faculty of Pharmacy, Iasi, Romania
Emmanoel V. CostaDepartment of Chemistry, Federal University of Amazonas
(UFAM), Manaus, AM, Brazil
Anine CrousLaser Research Centre, Faculty of Health Sciences, University of
Johannesburg, Johannesburg, South Africa
Qingbin CuiDepartment of Pharmaceutical Sciences, College of Pharmacy and
Health Sciences, St. John’s University, Queens, NY, USA
Carlos V. A. da SilvaMetabolomics and Mass Spectrometry Research Group,
University of the State of Amazonas (UEA), Manaus, AM, Brazil
Department of Chemistry, Federal University of Amazonas (UFAM), Manaus, AM,
Brazil
Daniella Da SilvaLaser Research Centre, Faculty of Health Sciences, University
of Johannesburg, Johannesburg, South Africa
Felipe M. A. da SilvaDepartment of Chemistry, Federal University of Amazonas
(UFAM), Manaus, AM, Brazil
Janaína Carla da SilvaLaboratory of Tumor Biology. Post-Graduation Program
in Applied Health Sciences, State University of West Paraná, Unioeste, Francisco
Beltrão, PR, Brazil
Kiran DahiyaDepartment of Radiation Oncology, Pt. BD Sharma PGIMS,
Rohtak, Haryana, India
Department of Biochemistry, Pt. BD Sharma PGIMS, Rohtak, Haryana, India
xl Contributors

Deepika DalalDepartment of Biochemistry, N. C College and Hospital, Panipat,
India
Somasri DamDepartment of Microbiology, The University of Burdwan, Burdwan,
India
Alakesh DasFaculty of Allied Health Sciences, Chettinad Academy of Research
and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai,
India
Amitava DasDepartment of Applied Biology, Council of Scientific & Industrial
Research-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad,
Telangana, India
Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India
Amlan DasNational Institute of Biomedical Genomics, Kalyani, West Bengal,
India
Chandrima DasBiophysics and Structural Genomics Division, Saha Institute of
Nuclear Physics, Kolkata, India
Homi Bhaba National Institute, Mumbai, India
Hiranmoy DasDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of
Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA
Joydeep DasDepartment of Chemistry, Physical Sciences, Mizoram University,
Aizawl, Mizoram, India
Moubonny DasDepartment of Microbiology, The University of Burdwan,
Burdwan, India
Neeladrisingha DasMolecular Endocrinology Laboratory, Department of Biosci-
ences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee,
Uttarakhand, India
Sarita DasMicrobiology Laboratory, Department of Botany, Berhampur Univer-
sity, Berhampur, Odisha, India
Simita DasDepartment of Chemistry, Indian Institute of Technology Dharwad,
Dharwad, Karnataka, India
Souvik DasDepartment of Neuroendocrinology & Experimental Hematology,
Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
Rakhi DasguptaDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Debduti DattaRNA Biology Research Laboratory, Molecular Genetics Division,
CSIR-Indian Institute of Chemical Biology, Kolkata, India
Dipak DattaDivision of Cancer Biology, CSIR-Central Drug Research Institute
(CDRI), Lucknow, India
Contributors xli

Soumasree DeDepartment of Chemistry, Biochemistry & Pharmaceutical
Sciences, University of Bern, Bern, Switzerland
Stefania Tagliari de OliveiraLaboratory of Tumor Biology. Post-Graduation
Program in Applied Health Sciences, State University of West Paraná, Unioeste,
Francisco Beltrão, PR, Brazil
Sujit Kumar DebnathDepartment of Biosciences and Bioengineering, Indian
Institute of Technology Bombay, Mumbai, India
DeepthiDivision of Molecular Biology, Faculty of Life Sciences, JSS Academy of
Higher Education & Research, Mysuru, Karnataka, India
Dikshita DekaDepartment of Medical Biotechnology, Faculty of Allied Health
Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hos-
pital and Research Institute (CHRI), Chennai, Tamil Nadu, India
Rohit K. DeshmukhDepartment of Applied Biology, Council of Scientific&
Industrial Research-Indian Institute of Chemical Technology (CSIR-IICT), Hydera-
bad, Telangana, India
Ravindra Pramod DeshpandeDepartment of Biotechnology and Bioinformatics,
School of Life Sciences, University of Hyderabad, Hyderabad, India
Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem,
NC, USA
Geetanjali DevabattulaDepartment of Biological Sciences (Regulatory Toxicol-
ogy), National Institute of Pharmaceutical Education and Research (NIPER), Hyder-
abad, Telangana, India
Naveen Kumar Devanga RagupathiHonorary Research Fellow Chemical and
Biological Engineering University of Sheffield, Sheffield, UK
Department of Clinical Microbiology, Christian Medical College Vellore, Vellore,
Tamil Nadu, India
Pujayita DevguptaDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Arikketh DeviStem Cell Biology Laboratory, Department of Genetic Engineering,
School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of
Science and Technology, Chennai, Tamil Nadu, India
Kuntal DeyInstitute of Veterinary Physiology, University of Zurich, Zurich,
Switzerland
Tuli DeyInstitute of Bioinformatics and Biotechnology, Savitribai Phule Pune
University, Pune, Maharashtra, India
Rakesh DhankharDepartment of Radiation Oncology, Pt. BD Sharma PGIMS,
Rohtak, Haryana, India
xlii Contributors

Rajib DharStem Cell Biology Laboratory, Department of Genetic Engineering,
School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of
Science and Technology, Chennai, Tamil Nadu, India
V. Violet DhayabaranDepartment of Biotechnology and Bioinformatics, Bishop
Heber College (Autonomous), Tiruchirappalli, India
Monisha DhimanDepartment of Microbiology, School of Basic Sciences, Central
University of Punjab, Bathinda, Punjab, India
Mayuri DholariaDepartment of Medical Technology, Naran Lala College of
Professional and Applied Sciences, Navsari, Veer Narmad South Gujarat University,
Surat, India
Anil K. DhullDepartment of Radiation Oncology, Pt. BD Sharma PGIMS, Rohtak,
Haryana, India
Saurav DoshiInstitute of Bioinformatics and Biotechnology, Savitribai Phule Pune
University, Pune, Maharashtra, India
Kamal DuaDiscipline of Pharmacy, Graduate School of Health, University of
Technology Sydney, Ultimo, NSW, Australia
Australian Research Centre in Complementary and Integrative Medicine, Faculty of
Health, University of Technology Sydney, Ultimo, NSW, Australia
Shilpee DuttShilpee Dutt Laboratory, Tata Memorial Centre, Advanced Centre for
Treatment, Research and Education in Cancer, Navi Mumbai, India
Homi Bhabha National Institute, Mumbai, India
Ashmita DuttaHuman Genetics Unit, Indian Statistical Institute, Kolkata, West
Bengal, India
Parijat DuttaDepartment of Genetic Engineering, Faculty of Engineering and
Technology, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India
Bilikere S. DwarakanathCentral Research Facility, Sri Ramachandra Institute of
Higher Education and Research, Chennai, India
Jesucastin EdwardDepartment of Biotechnology and Bioinformatics, Bishop
Heber College (Autonomous), Affiliated to Bharathidasan University,
Tiruchirappalli, Tamil Nadu, India
Zin Zin EiDepartment of Biochemistry and Microbiology, Faculty of Pharmaceu-
tical Sciences, Chulalongkorn University, Bangkok, Thailand
Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceu-
tical Sciences, Chulalongkorn University, Bangkok, Thailand
Uju Dorathy Iliemene EjikeDepartment of Biochemistry, Faculty of Science &
Technology, Bingham University, Karu, Nasarawa, Nigeria
Contributors xliii

Sonaa ElangoDepartment of Life Sciences, School of Natural Sciences, Univer-
sity of Suwon, Hwaseong-si, Republic of Korea
Binil EldhoseSchool of Medicine, Uniformed Services University of Health Sci-
ences (USUHS), Bethesda, MD, USA
Mohamed El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain
Shams University, Cairo, Egypt
Department of Pharmaceutical Biology, German University in Cairo, Cairo, Egypt
Perumal ElumalaiDepartment of Pharmacology, The Blue Lab, Molecular Med-
icine and Toxicology Division, Saveetha Dental College, Saveetha Institute of
Medical and Technical Sciences, Chennai, TN, India
Devaraj EzhilarasanDepartment of Pharmacology, The Blue Lab, Molecular
Medicine and Toxicology Division, Saveetha Dental College, Saveetha Institute of
Medical and Technical Sciences, Chennai, TN, India
Shaimaa FayezDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams
University, Cairo, Egypt
Riley FeserDepartment of Biology, Brandon University, Brandon, MB, Canada
Allen J. FreddyDepartment of Zoology, Madras Christian College, Chennai, TN,
India
Dhananjaya G.Department of Chemistry, Indian Institute of Technology
Dharwad, Dharwad, Karnataka, India
Shreyas R. GaikwadDepartment of Immunotherapeutics and Biotechnology, and
Center for Tumor immunology and Targeted Cancer Therapy, Texas Tech University
Health Sciences Center, Abilene, TX, USA
Prajakta GaikwadInstitute of Bioinformatics and Biotechnology, Savitribai Phule
Pune University, Pune, Maharashtra, India
Mariam I. Gamal ElDinDepartment of Pharmacognosy, Faculty of Pharmacy,
Ain Shams University, Cairo, Egypt
Harsha GanesanDepartment of Medical Biotechnology, Faculty of Allied Health
Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hos-
pital and Research Institute (CHRI), Chennai, Tamil Nadu, India
Matheus Ricardo GarbimLaboratory of Tumor Biology. Post-Graduation Pro-
gram in Applied Health Sciences, State University of West Paraná, Unioeste,
Francisco Beltrão, PR, Brazil
Anshoo GautamDivision of Molecular and Radiation Biosciences, Institute of
Nuclear Medicine and Allied Sciences, DRDO, New Delhi, India
Sukanya GayanInstitute of Bioinformatics and Biotechnology, Savitribai Phule
Pune University, Pune, Maharashtra, India
xliv Contributors

Blassan P. GeorgeLaser Research Centre, Faculty of Health Sciences, University
of Johannesburg, Johannesburg, South Africa
Sajan GeorgeLaser Research Centre, Faculty of Health Sciences, University of
Johannesburg, Johannesburg, South Africa
School of Biosciences and Technology, Vellore Institute of Technology, Vellore,
Tamil Nadu, India
Faezeh GhorbanizamaniFaculty of Science, Biochemistry Department, Ege Uni-
versity, Izmir, Turkey
Amlan GhoshGenetics of Non-communicable Diseases, Department of Life Sci-
ences, Presidency University, Kolkata, India
Chandrachur GhoshMolecular Endocrinology Laboratory, Department of Bio-
sciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee,
Uttarakhand, India
Mayukh GhoshDepartment of Veterinary Physiology and Biochemistry, RGSC,
Banaras Hindu University, Mirzapur, Uttar Pradesh, India
Faculty of Veterinary and Animal Sciences, Rajiv Gandhi South Campus, Banara
Hindu University, Mirzapur, Uttar Pradesh, India
Mrinal K. GhoshCancer Biology and Inflammatory Disorder Division, Council of
Scientific and Industrial Research-Indian Institute of Chemical Biology (CSIR-
IICB), Kolkata, India
Noyel GhoshDivision of Molecular Medicine, Bose Institute, Kolkata, India
Priyanka GhoshDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Rita GhoshDepartment of Biochemistry and Biophysics, University of Kalyani,
Kalyani, West Bengal, India
Sandip GhoshDepartment of Neuroendocrinology & Experimental Hematology,
Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
Sayantan GhoshDepartment of Biochemistry and Medical Biotechnology, Stem
Cell Research and Application Unit, Calcutta School of Tropical Medicine, Kolkata,
West Bengal, India
Sougata GhoshDepartment of Microbiology, School of Science, RK University,
Rajkot, Gujarat, India
Subhashis GhoshNational Institute of Biomedical Genomics, Kalyani,
West Bengal, India
Sukanya GhoshReceptor Biology and Tumor Metastasis, Chittaranjan National
Cancer Institute, Kolkata, West Bengal, India
Contributors xlv

Syamantak GhoshRNA Biology Research Laboratory, Molecular Genetics Divi-
sion, CSIR-Indian Institute of Chemical Biology, Kolkata, West Bengal, India
Daniel A. GideonDepartment of Biotechnology and Bioinformatics, Bishop Heber
College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli,
Tamil Nadu, India
Scintelligent Biotechnology Solutions, Tiruchirappalli, Tamil Nadu, India
Lingamallu GiribabuPolymers and functional materials Division, CSIR-Indian
Institute of Chemical Technology, Hyderabad, Telangana, India
Agnishwar GirigoswamiMedical Bionanotechnology, Faculty of Allied Health
Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of
Research and Education, Chennai, India
Koyeli GirigoswamiMedical Bionanotechnology, Faculty of Allied Health Sci-
ences, Chettinad Hospital and Research Institute, Chettinad Academy of Research
and Education, Chennai, India
Dhanavathy GnanasampanthapandianCancer Science Laboratory, Department
of Biotechnology, School of Bioengineering, SRM Institute of Science and Tech-
nology, Chengalpattu, India
Chandraiah GoduguDepartment of Biological Sciences (Regulatory Toxicol-
ogy), National Institute of Pharmaceutical Education and Research (NIPER),
Hyderabad, Telangana, India
Shivani GokaniDepartment of Pharmacology, SVKM’s Dr. Bhanuben Nanavati
College of Pharmacy, Vile Parle (West), Mumbai, India
Levin Anbu GomezDepartment of Biotechnology, School of Agriculture and
Biosciences, Karunya Institute of Technology and Sciences (Deemed to be Univer-
sity), Coimbatore, Tamil Nadu, India
Rhea Conchita GonsalvesDepartment of Biochemistry, Indian Academy Degree
College–Autonomous, Bengaluru, India
T. S. GopenathDepartment of Biotechnology & Bioinformatics, JSS Academy of
Higher Education & Research, Mysuru, Karnataka, India
Anindita GoswamiBiomedical Genetics Laboratory, Department of Zoology, The
University of Burdwan, Burdwan, West Bengal, India
Lipsy GoyalDivision of Molecular and Radiation Biosciences, Institute of Nuclear
Medicine and Allied Sciences, DRDO, New Delhi, India
Adriana GrigorasFaculty of Medicine, Department of Morphofunctional Sci-
ences I,“Grigore T. Popa”University of Medicine and Pharmacy, Iasi, Romania
Eray Metin GulerDepartment of Medical Biochemistry, University of Health
Sciences Turkey, Hamidiye School of Medicine, Istanbul, Turkey
xlvi Contributors

Department of Medical Biochemistry, University of Health Sciences Turkey,
Haydarpasa Numune Health Application and Research Center, Istanbul, Turkey
Vinoth Prasanna GunasekaranAmity Institute of Biotechnology, Amity Univer-
sity, Mumbai, India
Anshika GuptaDepartment of Biosciences, Sri Guru Gobind Singh College,
Chandigarh, India
Charu GuptaAmity Institute of Herbal Research & Studies, Amity University-
Uttar Pradesh, Noida, India
Kirti GuptaSub Divisional Hospital Meham, Rohtak, India
Sumiran Kumar GurungSchool of Life Sciences, Jawaharlal Nehru University,
New Delhi, India
Devaraj HalagowderDepartment of Zoology, University of Madras, Chennai,
Tamilnadu, India
Surajit HansdaDepartment of Biochemistry and Biophysics, University of
Kalyani, Kalyani, West Bengal, India
Shagufta HaqueDepartment of Applied Biology, CSIR-Indian Institute of Chem-
ical Technology, Hyderabad, Telangana State, India
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, UP, India
Syed Ehtaishamul HaqueDepartment of Pharmacology, School of Pharmaceuti-
cal Education and Research, Jamia Hamdard, New Delhi, India
A. Kühnel HaraldFH-Campus Vienna, Department of applied live science,
Section of Bioengineering, Vienna, Austria
Teena HaritwalRadiation Genetics and Epigenetics Department, Institute of
Nuclear Medicine and Allied Sciences, Delhi, India
Mohd. Rahil HasanDepartment of Biotechnology, School of Chemical and Life
Sciences, New Delhi, India
Gabriela HenríquezDepartment of Environmental Science and Engineering, The
University of Texas at El Paso (UTEP), El Paso, TX, USA
Sourav Hom ChoudhuryRNA Biology Research Laboratory, Molecular Genetics
Division, CSIR-Indian Institute of Chemical Biology, Kolkata, West Bengal, India
Lucian HritcuDepartment of Biology, Alexandru Ioan Cuza University of Iasi,
Faculty of Biology, Iasi, Romania
Pilaiwanwadee HutamekalinPrince of Songkla University, Songkhla, Thailand
Ashif IqubalDepartment of Pharmacology, School of Pharmaceutical Education
and Research, Jamia Hamdard, New Delhi, India
Contributors xlvii

Maria IshaqueDepartment of Biotechnology, Jaypee Institute of Information
Technology, Noida, India
Johirul IslamDepartment of Toxicology, Jamia Hamdard, New Delhi, India
Saifudeen IsmaelDepartment of Anatomy and Neurobiology, College of Medi-
cine, University of Tennessee Health Science Center, Memphis, TN, USA
Amteshwar S. JaggiDepartment of Pharmaceutical Sciences and Drug Research,
Punjabi University, Patiala, Punjab, India
Rifika JainDepartment of Biomedical Sciences, University of Illinois-College of
Medicine, Rockford, IL, USA
Joel JamesDepartment of Medicine, Department of Physiology, University of
Arizona, Tucson, AZ, USA
Department of Medicine, Division of Endocrinology, University of Arizona College
of Medicine, Tucson, AZ, USA
Monika JangraDepartment of Zoology, Research Scholar, Chaudhary Bansi lal
University, Bhiwani, Haryana, India
Megala JayaramanDepartment of Genetic Engineering, Faculty of Engineering
and Technology, SRM Institute of Science and Technology, Chennai, Tamil Nadu,
India
Selvaraj JayaramanDepartment of Biochemistry, Saveetha Dental College &
Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS),
Saveetha University, Chennai, India
T. Jesse JoelDepartment of Biotechnology, School of Agriculture and Biosciences,
Karunya Institute of Technology and Sciences (Deemed to be University), Coimba-
tore, Tamil Nadu, India
J. JeyakanthanDepartment of Bioinformatics, Alagappa University Science
Block, Karaikudi, Tamil Nadu, India
Jobin JohnDepartment of Biotechnology, School of Agriculture and Biosciences,
Karunya Institute of Technology and Sciences (Deemed to be University), Coimba-
tore, Tamil Nadu, India
Gaurav KaithwasDepartment of Pharmaceutical Sciences, Babasaheb Bhimrao
Ambedkar University, Lucknow, Uttar Pradesh, India
Ramaswamy KalyanasundaramDepartment of Biomedical Sciences, University
of Illinois College of Medicine, Rockford, IL, USA
Akshay KaneInstitute of Bioinformatics and Biotechnology, Savitribai Phule Pune
University, Pune, Maharashtra, India
Anbarasu KannanDepartment of Protein Chemistry and Technology, CSIR-
Central Food Technological Research Institute, Mysore, India
xlviii Contributors

Academy of Scientific and Innovative Research (AcSIR), CSIR-Central Food Tech-
nological Research Institute (CSIR-CFTRI) Campus, Mysore, India
B. M. KantheshDivision of Molecular Biology, Faculty of Life Sciences, JSS
Academy of Higher Education & Research, Mysuru, Karnataka, India
Arvinder K. KapurQIAGEN Technical Support, Germantown, MD, USA
Umran Karabulut DoganDepartment of Obstetrics and Gynecology, University
of Inonu, Faculty of Medicine, Malatya, Turkey
Prashanthi KaryalaDepartment of Biotechnology, Faculty of Life and Allied
Health Science, M S Ramaiah University of Applied Sciences, Bengaluru, India
Meena KatariaICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly,
Uttar Pradesh, India
Ankur KaulDivision of Cyclotron and Radiopharmaceutical Sciences (DCRS),
Institute of Nuclear Medicine and Allied Sciences (INMAS)-DRDO, Delhi, India
Sharanjot KaurDepartment of Microbiology, School of Basic Sciences, Central
University of Punjab, Bathinda, Punjab, India
Sukhchain KaurDepartment of Microbiology, School of Basic Sciences, Central
University of Punjab, Bathinda, Punjab, India
Antholi Keloth KavyaDepartment of Biochemistry, Co operative Institute of
Health Sciences, Kannur, Kerala, India
Minna KellomäkiBiomaterials and Tissue Engineering Group, BioMediTech,
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
Anjul KhadriaStructural Biology and Nanomedicine Laboratory, Department of
Biotechnology and Medical Engineering, National Institute of Technology,
Rourkela, Odisha, India
Andrew and Peggy Cherng Department of Medical Engineering, California Institute
of Technology, Pasadena, CA, USA
Mohd Sajid KhanDepartment of Biochemistry, Faculty of Life Sciences, Aligarh
Muslim University, Aligarh, Uttar Pradesh, India
Rahul KhanDepartment of Human Genetics and Molecular Medicine, Central
University of Punjab, Bathinda, India
Vishal KhatriDepartment of Biomedical Sciences, University of Illinois College
of Medicine, Rockford, IL, USA
Sartaj KhuranaAmity Institute of Biotechnology, Amity University, Noida, Uttar
Pradesh, India
Amity Institute of Molecular Medicine and Stem Cell Research, Amity University,
Noida, Uttar Pradesh, India
Contributors xlix

Huriye Senay KiziltanDepartment of Radiation Oncology, University of Health
Sciences, Başakşehir Çam and Sakura City Hospital,İstanbul, Turkey
Abdurrahim KocyigitDepartment of Medical Biochemistry, Bezmialem Vakif
University School of Medicine, Istanbul, Turkey
Bezmialem Vakif University Traditional and Complementary Medicine Advanced
Research Applications and Research Center, Istanbul, Turkey
Hector H. F. KoolenMetabolomics and Mass Spectrometry Research Group,
University of the State of Amazonas (UEA), Manaus, AM, Brazil
Hari K. KoulDepartment of Biochemistry & Molecular Biology, Urology and
Interdisciplinary Oncology, Stanley S. Scott Cancer Center, LSUHSC School of
Medicine, New Orleans, LA, USA
Sweaty KoulDepartments of Urology, Interdisciplinary Oncology, and Stanley S.
Scott Cancer Center, School of Medicine LSUHSC, New Orleans, LA, USA
Ahmed Serdar KozanogluDepartment of Pharmaceutical Technology, Faculty of
Pharmacy, Bezmialem Vakif University, Istanbul, Turkey
Sneha KrishnamoorthyDepartment of Biochemistry, Karpagam Academy of
Higher Education, Coimbatore, Tamil Nadu, India
Abhaya KrishnanDepartment of Biochemistry, Karpagam Academy of Higher
Education, Coimbatore, Tamil Nadu, India
Binod KumarNewborn Screening Program, and Department of Pediatrics, UMass
Medical School, Worcester, MA, USA
Dinesh KumarDivision of Molecular Biology, National Institute of Cancer
Prevention and Research, Indian Council of Medical Research, Noida, India
Kuldeep KumarDepartment of Pharmaceutical Sciences and Drug Research,
Punjabi University, Patiala, Punjab, India
Mandeep KumarPharmacology and Toxicology, University of Genoa, Genoa,
Italy
Puneet KumarDepartment of Pharmacology, Central University of Punjab,
Bathinda, India
Rajappan Chandra Satish KumarInterdisciplinary Institute of Indian System of
Medicine, SRM Institute of Science and Technology, Chengalpattu, India
Rajesh KumarDepartment of Biochemistry, World College of Medical Sciences
and Research, Jhajjar, Haryana, India
Rajesh KumarDepartment of Veterinary Physiology and Biochemistry, Lala
Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India
l Contributors

Sachin KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja
Ranjit Singh Punjab Technical University, Bathinda, India
Santosh KumarDepartment of Biochemistry, All India Institute of Medical Sci-
ences, Patna, India
Vivek KumarR&D Dept, Shanghai Proton and Heavy Ion Centre (SPHIC),
Shanghai, China
K. Kumar EbenezarNatural Medicine and Molecular Physiology Lab, Faculty of
Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Acad-
emy of Research & Education, Kelambakkam, Chengalpattu Dt, TN, India
R. Ileng KumaranBiology Department, Farmingdale State College, Farmingdale,
NY, USA
Mohanya KumaravelDepartment of Biotechnology, School of Agriculture and
Bioscience, Karunya Institute of Technology and Sciences (Deemed-to-be Univer-
sity), Coimbatore, Tamil Nadu, India
Sangeeta KumariSchool of Life Sciences, Jawaharlal Nehru University,
New Delhi, India
Chanakya Nath KunduCancer Biology Division, School of Biotechnology,
Kalinga Institute of Industrial Technology (KIIT), Deemed to be University,
Bhubaneswar, Odisha, India
Mousumi KunduDivision of Molecular Medicine, Bose Institute, Kolkata, India
Ajaikumar B. KunnumakkaraDepartment of Biosciences and Bioengineering,
Indian Institute of Technology (IIT) Guwahati, Guwahati, Assam, India
Vijay Kumar KutalaDepartment of Clinical Pharmacology and Therapeutics,
Nizam Institute of Medical Sciences (NIIMS), Hyderabad, India
Rangaswamy LakshminarayanaDepartment of Microbiology and Biotechnol-
ogy, Jnana Bharathi Campus, Bangalore University, Bengaluru, India
Sujata LawDepartment of Biochemistry and Medical Biotechnology, Stem Cell
Research and Application Unit, Calcutta School of Tropical Medicine, Kolkata,
West Bengal, India
Mubarak Labaran LimanDepartment of Science Laboratory Technology, Nuhu
Bamalli Polytechnic, Zaria, Kaduna, Nigeria
S. LogeshDepartment of Biotechnology & Bioinformatics, JSS Academy of
Higher Education & Research, Mysuru, Karnataka, India
Ludmila LozneanuFaculty of Medicine, Department of Morphofunctional Sci-
ences,“Grigore T. Popa”University of Medicine and Pharmacy Iasi, Ias‚i, Romania
Nilkamal MahantaDepartment of Chemistry, Indian Institute of Technology
Dharwad, Dharwad, Karnataka, India
Contributors li

Sailendra Kumar MahantaDepartment of Pharmacy, School of Health Sciences,
The Assam Kaziranga University, Jorhat, Assam, India
Manas K. MahapatraDepartment of Biochemistry, School of Life Sciences,
Central University of Rajasthan, Ajmer, Rajasthan, India
Amit K. MaitiDepartment of Genetics and Genomics, Mydnavar, Troy, MI, USA
Sujit MaitiDepartment of Biology, Brandon University, Brandon, MB, Canada
Biswanath MaityCentre of Biomedical Research, Sanjay Gandhi Post-Graduate
Institute of Medical Sciences campus, Lucknow, UP, India
Swagata MajumdarCenter for Liver Research, School of Digestive and Liver
Diseases, Institute of Post Graduate Medical Education and Research, Kolkata, India
Mousumi MajumderDepartment of Biology, Brandon University, Brandon, MB,
Canada
M. K. MakalakshmiDepartment of Medical Biotechnology, Faculty of Allied
Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad
Hospital and Research Institute (CHRI), Chennai, Tamil Nadu, India
Sweta MakwanaDepartment of Biochemistry, School of Life Sciences, Central
University of Rajasthan, Ajmer, Rajasthan, India
Sarubala MalayaperumalDepartment of Medical Biotechnology, Faculty of
Allied Health Sciences, Chettinad Academy of Research and Education (CARE),
Chettinad Hospital and Research Institute (CHRI), Chennai, Tamil Nadu, India
Ashish Kumar MalikDepartment of Psychiatry, N. C. Medical College and
Hospital, Israna, Israna, Panipat, Haryana, India
Amritlal MandalDepartment of Physiology, University of Arizona, Tucson, AZ,
USA
Chandi C. MandalDepartment of Biochemistry, School of Life Sciences, Central
University of Rajasthan, Ajmer, Rajasthan, India
Paramita MandalBiomedical Genetics Laboratory, Department of Zoology, The
University of Burdwan, Burdwan, West Bengal, India
Reji ManjunathanMulti-Disciplinary Research Unit, Chengalpattu Government
Medical College, Kanchipuram, India
Zoya MannStem Cell Facility, DBT Centre of Excellence for Stem Cell Research,
All India Institute of Medical Sciences, New Delhi, India
Anil K. ManthaDepartment of Zoology, School of Biological Sciences, Central
University of Punjab, Bathinda, Punjab, India
Gauta Gold MatlouLaser Research Centre, Faculty of Health Sciences, Univer-
sity of Johannesburg, Johannesburg, South Africa
lii Contributors

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Abb. 148. Bauer aus Weißig.
Liebhaberaufnahme von H. Engert in Dresden. (Zu Seite 160.)
In Schöna und Reinhardtsdorf wird noch jetzt der Todbaum, eine
aufgeputzte Birke, unter Gesang durchs Dorf getragen. Die Kinder
selbst ziehen mit grünen Maien hinterher. Fällt Lätare zu zeitig, daß
das Laub noch nicht heraus ist, dann legt man vorher die
Birkenreiser ins Wasser, um die Knospen zu treiben. Dieser Zweig
wurde dann später bei Aufgang der Sonne in fließendes Wasser
geworfen, um den Tod zu ersäufen. Während des Umzuges durchs
Dorf erklang das Lied:

Lobedanz.
Den Tod, den Tod haben wir ausgetrieben,
Den lieben Sommer bringen wir wieder.
Die Mädchen und die Maien;
Da wachsen Blümlein und Feigeln,
Wir haben getrieben, wir haben gejagt
Durch Hamburg, durch die große Stadt,
Durch Magdeburg über die Brücke.
Gott gebe Euch Gelücke!
An den Todbaum werden die erhaltenen Geschenke gehängt. In
Rathmannsdorf bei Schandau hat sich noch ein letzter Rest dieses
alten Brauches insofern erhalten, als zu Ostern mit bunten
Papierstreifen, Eierschalen u. s. w. aufgeputzte Birken als
Osterbäume vor den Häusern aufgestellt werden. Doch ist ein
Umzug oder ein Gesang nicht mehr damit verbunden.
Geographische Erinnerungen an die Ersäufung der Todpuppe
finden sich in mehreren Benennungen, z. B. der Todhübel bei
Ostrau, ein Waldsteig bei Kleinhennersdorf heißt der Todweg, ebenso
der Todweg nördlich von Cunnersdorf.
Dieser Brauch des Todaustreibens
war im Gebirge wohl am originellsten
ausgebildet. Die anderen sogenannten
Feste haben dergleichen Eigenarten nicht aufzuweisen. Nur ein
ursprünglich wohl lokal ganz beschränktes Fest mag noch etwas
näher betrachtet werden. Daß es schon aus recht alter Zeit stammt,
mag wohl schon der seltsame, in seiner jetzigen Gestalt
unverständlich gewordene Name „Lobedanz“ beweisen. Allerdings
wird auf diesem Feste, wie ursprünglich wohl bei allen, auch
getanzt; aber daraufhin darf man das Wort „danz“ nicht deuten.
Vielmehr soll es Lob- und Dankfest heißen und ist ein kirchliches
Fest, das 14 Tage nach Pfingsten — nach unsicherer Vermutung und
Überlieferung — wohl entstanden ist, als die Orte Schöna und
Reinhardsdorf von einer schweren Pest heimgesucht und dann davon
befreit wurden oder überhaupt verschont geblieben waren. Nach der
kirchlichen Feier folgt am Abend ein freier Tanz und dabei, jedenfalls

Mundart in der Sächsischen
Schweiz.
mit besonderer Beziehung zu der Veranlassung des Festes, der
„Blumentanz“. Blumen und Laubschmuck bleiben aber zur
Erinnerung noch erhalten, bis vier Wochen darauf der „Rascheltanz“
damit aufräumt.
Die in der Sächsischen Schweiz vom
Volk gesprochene Mundart ist die
obersächsische. Diese Mundart herrscht
im größten Teile des nordwestlichen Sachsen und noch in die Provinz
Sachsen hinein; ihre Südgrenze findet sich am höheren Erzgebirge,
im Osten endigt sie an der Lausitzer Grenze. Der besondere Zweig
dieser Mundart, der namentlich im Elbtal und in dem
Sandsteingebirge verbreitet wird, ist die meißnische Mundart. Im
Erzgebirge und im Lausitzer Gebirge haben sich besondere
Mundarten entwickelt, in der Sächsischen Schweiz nicht. Trotzdem
findet ein geübtes Ohr bald den Unterschied in der Sprache eines
Talbewohners unterhalb Dresdens und eines Gebirgsbewohners aus
den Dörfern oberhalb Königsteins heraus.
K. Franke gibt in der Sächsischen Volkskunde von Wuttke eine
ganze Reihe von Wörtern, von denen er meint, sie kehrten in den
meisten obersächsischen Mundarten wieder, z. B. apblatn (einzelne
Blätter von den Kräutern nehmen), aptofln (ausschelten), ärpern
(Kartoffeln), bärladsch (Filzschuh), bemme (ein flachgeschnittenes
Stück Brot), betäpperd (verblüfft), blaudse (Brust), breedn (fertig
bringen), tattrich (Zittern), debs (Lärm), tembrn (die Zeit
vertrödeln), titsche (Sauce, Verlegenheit), towrich (schwül), tutch
(dumm), eschrn (sich abmühen). Diese wenigen genügen hier, um
den eigentümlichen Wortschatz dieser Mundart zu kennzeichnen. Es
wird hier vielleicht noch besser am Platze sein, zum Schluß unserer
ganzen Darstellung eine Probe der meißnischen Mundart und ganz
besonders aus der Sächsischen Schweiz selbst zu geben. Wir
entnehmen diese Probe einem älteren, immer noch sehr geschätzten
Werke von K. Preusker (Blicke in die Vaterländische Vorzeit, Leipzig
1843, II. 56); und wenn auch die Schreibweise nicht mehr den
neuen Anforderungen einer schärfer unterscheidenden
Sprachwissenschaft genügt, so scheint uns doch eine Umschmelzung

für unsere Darstellung nicht am Platze, namentlich da die Zeit der
ersten Niederschrift Preuskers schon um 60 Jahre zurückliegt.
Abb. 149. Hochzeitszug bei Naundorf.
Liebhaberaufnahme von H. Engert in Dresden. (Zu Seite 160.)
Mundart der Elbgegend um Hohnstein und Wehlen.
Ein Steinbrecher bietet sich einer von der Bastei
herabkommenden Gesellschaft als Führer an und erklärt nun das
Bemerkenswerteste nach seiner Weise: „Wenn Se hier fremde sein
duhn un nich wissen, wo der Wahk giht, su will ich Se führen, wenn
Se wunn. Sähn Se hier ungen leit Roaden (Rathen) un doa uben leit
eene oale Burg, weil Se oaber schune runger sein, doa wären Se
nich erscht roan steign; man sieht nischt wedder als en oaln Durm,

un drunger ees e Kaller. In oalen Zeiden han eemoal oale Ridder
druben gewohnt, ich weeß oaber nischt darvunn, un’s gibt wull lange
keene raichten me, wenn oach manche so duhn, als wärn’s welche.
Uff dr linken Seite ees de Elbe; se hat wedder uben viäl Strum, doa
missen se Ucksen firspann, wenn sie ni furt kinn. Ooch’s oale
Dampfschiff (das zuerst erbaute) ees schund uft liegen gebliebn. ’s
ies en schund raicht, weil se unsern Schiffleiden viäl Abbruch dhun.
Jetzt sein mer bale unger der Bastei. Do iber uns is a Fels, der heeßt
de Steenschloider, do haben de Raiber sonst Steene bis uff de
Schiffe in der Elbe geschmissen, die se han beroben wunn; ’s is aber
nicht wohr; ’s is gar weit nibber, un wenn mer von dort uben en
Steen nider werfen dhut, kommt er nur e klee Stückel her un dhut
gleich an Felsen runger fallen. Sähn Se, hier han mir Steenbrecher
eene Wand gefällt, e Sticke dervund leit in der Elbe. ’s ees duch
immer besser, als wenn’s uffn Steenbrechern liegen dhäte. Se globen
mersch wuhl nich? Vor dreizen Jahren, ’s war grade na Fingsten,
kamen eemoal dreizen unger eene sicke Wand, ochte waren glei dut
geschmissen, oaber finfe wurden erschtn sechsten Toag
rausgesoh’n. Ich hoa sälber mit gereimt. Un wie se raus kummen
dhaten, doa kunnten se nich giähn, se läbten oaber noch, un weil se
so hungrich gewiäßt waren, doa hatten se vun en duten
Kammeraden e Stickel abgeschniden un gegässen. ’s is och in en
Bichel gedruckt wurrn. Hier müßmer fix giähn, denn weil eene
Doafel doa stiht (zur Warnung wegen sich lösender
Sandsteinwände), doa werd wieder eene Wand fallen. Hernachens
kummer uff eene Wiese, doa giht’s bässer, die ees ä Sticke geflastert
(nämlich wegen darauf gefallener Sandsteine). Durt sähmer schund
Willstädtel (Wehlen, Wehlstädel). Ich hoa oach eene Schwester durt,
die hatte en Schiffmann, er dhate oaber in der Elbe ersaufen. De
Kerche ees oach racht schihn, eegentlich summer nachen Kinsten
(Königstein) giähn, oaber doas es zu weit, de Kinder mißmer oaber
durt doafen lassen. Un durt uben, übern Stadtel, is oach en oales
Schluß gewiäsen. Da hoat sich in e oales Gemeier vun de oalen
Riddern ä Schuster eigebaut un dhut sich stulz druf. — Ich muß
abber nu furt, denn weil ich kee Schild hoaben dhue, doa derf ich

kennen urdentlichen Führer machen. Bis Berne (Pirna) ees es nuch
anderthalb Stunden. Schloafen Se wuhl. ’s giht nu grade aus.“
Dergleichen Unterhaltungen und Belehrungen konnte man in
früheren Zeiten auch von den privilegierten Führern hören. Gerade
darum ist dieses Beispiel der Mundart hier am Platze, wo es sich
nicht bloß um die richtige Erkenntnis der Natur, sondern auch um
Mitteilungen aus der Volkskunde handelt. Das Führerwesen selbst
wird aber auch wohl bald der Vergangenheit angehören. Denn wo
eine Berglandschaft so bequem zugänglich gemacht ist und überall
genügende Wegweiser hat, wo die bekanntesten Wege so viel
begangen werden, und manche Teile parkartige Szenerien bieten: da
ist der Naturfreund nicht mehr auf fremde Führung angewiesen und
nimmt allein und ungestört die mannigfachen Schönheiten der
Sächsischen Schweiz tiefer in sich auf denn sonst.

Literatur.
A. von Gutbier, Geognostische Skizze aus der sächsischen
Schweiz. Leipzig 1858.
Hettner, Gebirgsbau und Oberflächengestaltung der
sächsischen Schweiz. 1887. — (Forschungen zur
deutschen Landes- und Volkskunde. Band 2.)
C. Gurlitt, Das Schloß zu Meißen. Dresden 1881.
Deichmüller, Sachsens vorgeschichtliche Zeit. (Wuttkes
sächsische Volkskunde. 2. Aufl. Dresden 1901.)
R. Beck, Geologischer Wegweiser. Dresdner Elbtalgebiet.
Berlin 1897.
Erläuterungen zur geologischen Karte von Sachsen.
R. Beck, Die sächsische Schweiz und der Elbdurchbruch
zwischen Tetschen und Pirna. (Himmel und Erde II. 4. S.
182. Berlin 1890.)
O. Schulze, Kolonisation und Germanisierung des Gebiets
zwischen Saale und Elbe. Leipzig 1896.
M. Wießner, Die Akademie der bildenden Künste zu
Dresden. Dresden 1864.
Über Berg und Tal, Organ des Gebirgsvereins für die
sächsische Schweiz. Seit 1878. (Aufsätze von Martin
Teile, Meiche, Lehmann u. a. )
O. Lehmann, Dresden, sächsische Schweiz und Lausitzer
Gebirge. 5. Aufl. Leipzig und Wien 1900. (Meyers
Reisebücher.)
A. Penck, Das deutsche Reich (A. Kirchhoff, Länderkunde
von Europa. Prag und Leipzig 1885).

Nikolai, Wegweiser durch die sächsische Schweiz. Pirna
1901.
Götzinger, Schandau und seine Umgebung — oder
Beschreibung der sogen. sächsischen Schweiz. Bautzen
1804.
A. Schiffner, Beschreibung der gesamten sächsisch-
böhmischen Schweiz in ihrer neusten Gestalt. Meißen o.
J. (1835).
C. J. Weber, Deutschland oder Briefe eines in Deutschland
reisenden Deutschen. Band 3. Stuttgart 1834.
M. Chr. Weiß, Wanderungen in Sachsen, Schlesien, Glatz
und Böhmen. 2. Aufl. 2 Teile. Leipzig 1796/7.
Joh. Christ. Heik, Beschreibung des pirnischen
Sandsteingebirges. (Hamburger Magazin VI. 213 bis 219.
Hamburg 1750.)
O. v. Odeleben, Die topographische Aufnahme der
sächsischen Schweiz. Ein Kommentar zu der Karte der
Gegend von Hohnstein und Schandau. Dresden 1830.
M. Martin, Die Elbflößerei. (Beilage der A. Z. 1896. Nr. 273
u. 274.)
K. Berling, Das Meißner Porzellan und seine Geschichte.
Leipzig 1900.
G. Lehnert, Das Porzellan. Bielefeld und Leipzig 1902.
W. Schäfer, Die königl. Gemäldegalerie. Dresden 1860.
K. v. Weber, Aus vier Jahrhunderten. 2 Bände. Leipzig
1857.

Verzeichnis der Abbildungen.

Abb.  Seite
1. Der Liebethaler Grund. Lochmühle 2
2. Dresden von der Marienbrücke
gesehen 3
3. Altes Landhaus bei der Bahnwiese.
Oberlößnitz 4
4. Groß-Sedlitz bei Pirna. Schloßgarten 5
5. Die Begerburg im Plauischen Grunde6
6. Schloß Scharfenberg bei Meißen 7
7. Dohna 8
8. Schloß Weesenstein 9
9. Weesenstein vom Belvedere aus 11
10. Die Albrechtsburg in Meißen 13
11. Kötzschenbroda-Niederlößnitz 14
12. Hosterwitz bei Pillnitz 15
13. Keppmühle im Keppgrunde bei
Hosterwitz 17
14. Loschwitz 18
15. Loschwitz 19
16. Pavillon auf Körners Weinberg in
Loschwitz, wo Schiller wohnte 20
17. Talsiedelungen und Felsformen.
Lößnitzgrund 21
18. Jagdschloß Moritzburg 22
19. Partie aus Brießnitz 23
20. Meißen 25
21. Der Dom und die Albrechtsburg in
Meißen 26
22. Die große Appellationsstube in der
Albrechtsburg zu Meißen 27
23. Die Königl. Porzellan-Manufaktur in
Meißen 28
24. Drehen, Formen und Gießen in der
Königlichen Porzellan-Manufaktur zu
Meißen 29
25. Malersaal der Königl. Porzellan-

Manufaktur zu Meißen 30
26. Porzellanbrennofen der Königl.
Porzellan-Manufaktur zu Meißen 31
27. Meißener Gefäße in Scharffeuerfarben32
28. Das Mädchen aus der Fremde.
Erzeugnis der Königl. Porzellan-
Manufaktur zu Meißen
33
29. Der Große Markt in Meißen 34
30. Rote Stufen in Meißen 35
31. Dresden von der Bärbastei. 1820 36
32. Hof im Königl. Schlosse zu Dresden 37
33. Der Altmarkt mit dem Rathause zu
Dresden 38
34. Pirnaischer Platz in Dresden 39
35. Neustädter Markt in Dresden 40
36. Großer Ballsaal im Königl. Schlosse zu
Dresden 41
37. Gobelinzimmer im Königl. Schlosse zu
Dresden 42
38. Arbeitszimmer des Königs von Sachsen43
39. Palais und Teich im Großen Garten zu
Dresden 44
40. Der Zwinger in Dresden.
Gesamtansicht 45
41. Der Zwinger in Dresden 46
42. Äußere Ansicht des Zwingers 47
43. Der Zwingerteich in Dresden 48
44. Die Frauenkirche in Dresden 49
45. Ansicht von Dresden mit der Alten
Brücke 51
46. Belvedere und Landeplatz der
Dampfschiffe in Dresden 52
47. Treppe zur Brühlschen Terrasse in
Dresden 53
48. Die katholische Hofkirche und das
Königl. Schloß in Dresden 54
 

49. Die heilige Nacht. Gemälde von
Correggio in der Dresdener Galerie 55
50. Die Madonna mit dem heiligen Georg.
Gemälde von Correggio in der
Dresdener Galerie 56
51. Der Zinsgroschen. Gemälde von Tizian
in der Dresdener Galerie 57
52. Die Sixtinische Madonna. Gemälde von
Raffael in der Dresdener Galerie 58
53. Maria mit dem Jesusknaben. Gemälde
von Murillo in der Dresdener Galerie59
54. Der Galeriehof des Königl. Schlosses
zu Dresden 60
55. Die Gemäldegalerie in Dresden.
Fassade nach dem Theaterplatz 61
56. Die Königl. Kunstakademie in Dresden,
von der Neustadt gesehen 62
57. Die Königl. Kunstakademie in Dresden.
Ausstellungsbau 63
58. Das Hofopernhaus in Dresden 64
59. Das Königliche Schloß und die
Wettinsäule in Dresden 65
60. Weber-Denkmal in Dresden 66
61. Das Japanische Palais in Dresden 67
62. Die Kreuzschule und das Körner-
Denkmal in Dresden 68
63. Der Hauptbahnhof in Dresden 69
64. An der Elbe bei Königstein. Zeichnung
von Adrian Zingg. 1766 70
65. Schandau. Nach einem kolorierten
Stich von Adrian Zingg 71
66. Ausblick von der Bastei elbaufwärts73
67. Der Lilienstein 74
68. Bodenbach und die Schäferwand 75
69. Tetschen und Obergrund 76
70. Schloß zu Tetschen 77
 

71. Der Schreckenstein 78
72. Die Elbe bei Niedergrund 79
73. Die Elbe bei Wehlen, flußaufwärts
gesehen 80
74. Gasthaus an der Dürrkamnitz 81
75. Die Grundmühle 82
76. Die Wilde Klamm 83
77. Wilde Klamm. Dreyfußfelsen 84
78. Im Edmundsgrunde. Winterstimmung 85
79. Die Edmundsklamm 86
80. Herrnskretschen, von der Elbe
gesehen 87
81. Herrnskretschen. Talsiedelung 89
82. Die Obere Schleuse 91
83. Partie aus dem Kirnitzschtal bei Hinter-
Hermsdorf 92
84. Die Buschmühle im Kirnitzschtal 93
85. Lichtenhainer Wasserfall 94
86. Der Hockstein 95
87. Hohnstein und das Polenztal 96
88. Die Königskiefer über dem
Polenzgrunde 97
89. Der Eingang in den Liebethaler Grund98
90. Schloß Lohmen 99
91. Der Zscherregrund 100
92. Die Basteibrücke, vom Ferdinandstein
gesehen 101
93. Die Schwedenlöcher 102
94. Grundriß der Felsplatte des Gorisch103
95. Die Kleine Gans 104
96. Der Amselfall 105
97. Der Talwächter am Großen Dom 106
98. Eisgrotte in der Weberschlüchte 107
99. Bad Schweizermühle 108
100. Die Herkulessäulen bei Bad
Schweizermühle 109
 

101. Die Barbarine beim Pfaffenstein 110
102. Felsenturm an der Heiligen Stiege111
103. Am Wildschützensteige 112
104. Der Bloßstock, fälschlich Blaustock;
alleinstehender Felsen 113
105. Zuckerhut am Gabrielensteig im
Prebischgrunde 114
106. Felsentor im Uttewalder Grund 115
107. Tyssaer Wände nach Franzens Aussicht116
108. Eingang zur Götzinger-Höhle
(Diebeskeller) am Bärenstein 117
109. Der Naundorfer Bärenstein mit
schräger Klüftung, rechts schräge und
senkrechte Klüftung wechselnd 119
110. Im Tal oberhalb des Großen Domes 120
111. Aussicht von den Schrammsteinen 121
112. Aussicht vom Hohen Torstein über die
Schrammsteine, Ostertürme,
Schrammtürme und Dreifingerturm123
113. Das Pechofenhorn am Zeughauswege125
114. Verwitterung des Sandsteins auf dem
Gorisch 126
115. Höhlenartige Auswitterungen am Fuße
des Gorisch 127
116. Der Kuhstall 128
117. Der Kleinstein 129
118. Rostfarbene Auswitterungen am
Thürmsdorfer Diebeskeller (Götzinger-
Höhle) 130
119. Schwammartige Auswitterungen
oberhalb des Großen Domes 131
120. Auf dem Hohen Schneeberg 132
121. Der Gorisch 133
122. Auf dem Gipfel des Gorisch 134
123. Der Pfaffenstein. Gesamtansicht von
Südwesten gesehen 135
 

124. Stadt und Festung Königstein 136
125. Die Schrammsteine 137
126. Dittersbach 138
127. Das Prebischtor und der Rosenberg139
128. Am Rauschentor bei Schmilka 140
129. Schmilka 141
130. Das Felsentor auf dem Neurathen 142
131. Bastei von der Elbseite 143
132. Rathen 145
133. Ernte bei Weißig 146
134. Steinbruch in der alten Posta 147
135. Steinbruch in der alten Posta 148
136. Steinbruch in der alten Posta 149
137. Pirna und der Sonnenstein 151
138. Sebnitz 152
139. Topographischer Plan der Festung
Königstein 153
140. Stadt und Festung Königstein 155
141. Schandau 157
142. Die alte Burg Wehlen um 1755 158
143. Wehlen 159
144. Stadt und Schloß Hohnstein, vom
Hockstein 161
145. Hohnstein 162
146. Altes Häuschen im Dorfe Wehlen 163
147. Altes Haus im Dorfe Wehlen 164
148. Bauer aus Weißig 165
149. Hochzeitszug bei Naundorf 167

Register.
Affenstein 128.
Alberthafen 138.
Alberthöhe 10.
Albertitz 24.
Albrechtsburg (Meißen) 13 (Abb. 10). 26
(Abb. 21). 27 (Abb. 22). 33.
Altendorf 129.
Altzelle 28. 38.
Amselfall 90. 105 (Abb. 96).
Arkynnen 3.
Auswitterung 111. 130 (Abb. 118). 131
(Abb. 119).
Babisnauer Pappel 8.
Bahnwiese, Landhaus 4 (Abb. 3).
Barbarine 103. 110 (Abb. 101).
Bärenstein, Großer 108. 117. 119 (Abb.
109). 122. 131.
Bärenstein, Kleiner 106. 117. 122. 131.
Bärreute 85.
Basaltberge 74.

Bastei 67. 85. 88. 90. 115. 124. 132. 133.
143 (Abb. 131);
Ausblick elbaufwärts 73 (Abb. 66).
Basteibrücke 101 (Abb. 92).
Bauernhaus 160.
Begerburg 6 (Abb. 5).
Bergbau 10.
Bergwerk (Ort) 10.
Bernhardstein 117.
Berntitz 24.
Besiedelungsgeschichte 22 ff.
Bevölkerung 22 ff.;
ländliche 160 ff.;
Sitten 161.
Biela 94.
Bieler Grund 114.
Birkwitz 16.
Birkwitzer See 21.
Blasewitz 23.
Bloßstock (Blaustock) 103. 113 (Abb. 104).
Blumenfabrikation 146. 148.
Bodenbach 70. 75 (Abb. 78).
Böhmer Straße 127.
Böhmerwald 62.
Böhmisch-Kamnitz 79.
Bomätschen 138.

Bonnewitz 14.
Boritz 37.
Boxdorf 20.
Brand 84. 110. 124. 132.
Brießnitz 8. 23 (Abb. 19). 26. 35.
Bühlau 28.
Burkhardtswalde 8. 10.
Buschmühle 82. 93 (Abb. 84).
Cölln 22. 31.
Conradesdorf 24.
Conratiz 24.
Cossebaude 10. 14.
Cotta 57. 144.
Cottaer Spitzberg 76. 128.
Cunnersbach 72.
Cunnersdorf 72.
Cunnersdorfer Bach 94.
Daube 86.
Daubitz 126.
Diebeskeller 106. 111. 117 (Abb. 108).
Dittersbach 79. 124. 126. 127. 138 (Abb.
126).
Dohna 8 (Abb. 7). 10. 26. 144.
Döltzschen 10.

Dom, Großer 93. 120 (Abb. 110). 131 (Abb.
119).
Dreifingerturm 123 (Abb. 112).
Dresden 23. 24. 35 ff. 36 bis 40 (Abb. 31–
35). 51 (Abb. 45). 138. 141;
von der Marienbrücke gesehen 3 (Abb.
2);
Augustusbrücke 43;
Bevölkerung 57;
Belvedere 52 (Abb. 46);
Bibliothek 58;
Brühlsche Terrasse 45. 53 (Abb. 47);
Frauenkirche 36. 42. 49 (Abb. 44);
Gemäldegalerie 48 ff. 55–59 (Abb. 49–
53). 61 (Abb. 55);
Georgenschloß 40;
Großer Garten 41. 44 (Abb. 39);
Hauptbahnhof 69 (Abb. 63);
Hochschulen 58;
Japanisches Palais 58. 67 (Abb. 61);
Königl. Schloß 41–43 (Abb. 36–38). 54
(Abb. 48). 60 (Abb. 54). 65 (Abb. 59);
Körner-Denkmal 68 (Abb. 62);
Kreuzkirche 38;
Kreuzschule 68 (Abb. 62);
Kunstakademie 56. 62 (Abb. 56). 63
(Abb. 57);
Museum 56;
Opernhaus 56. 64 (Abb. 58);
Schulen 58;
Taschenberg 37;
Weber-Denkmal 66 (Abb. 60);
Wettinsäule 65 (Abb. 59);
Zwinger 39 ff. 45–48 (Abb. 40–43).

Dresdener Heide 16.
Dresdener Talbecken 5 ff.
Dreyfußfelsen 84 (Abb. 77).
Dürrkamnitzbach 79;
Gasthaus am 81 (Abb. 74).
Ebenheiten 68.
Edmundsklamm (Edmundsgrund) 80. 85.
86 (Abb. 79).
Eiland 94.
Eisenbahnverkehr 59.
Eishöhle (Eisgrotte) 93. 107 (Abb. 98).
Eiszeit 10. 72. 74.
Elbe 21. 67. 70 (Abb. 64). 77 ff. 79 (Abb.
72). 80 (Abb. 73). 87. 98. 136;
Brücken 136;
Dampfschiffahrt 136;
Flößerei 140;
Güterverkehr 140;
Häfen 138;
Schiffahrt 59;
Segelschiffahrt 138.
Elbsandsteingebirge, Aufbau 67 ff.
Elbtalgebirge 7.
Eulaer Bach 116.
Falkenstein 128.
Fastenbeten 161.
Ferdinandsklamm 79.
Forstmühle 98.

Franzens Aussicht 116.
Freiberg 29.
Fremdenweg 129.
Friedensburg 14 (Abb. 11). 15. 20.
Friedrichsgrund 16.
Gabrielensteig 103. 114 (Abb. 105).
Galitzstein 118.
Gamighügel 9.
Gans, Kleine 104 (Abb. 95).
Gauernitz 10.
Goës 144.
Goldene Höhe 8.
Goppeln 38.
Gorisch 74. 102. 103 (Abb. 94). 110. 111.
117. 118. 126 (Abb. 114). 127 (Abb. 115).
133 (Abb. 121). 134 (Abb. 122). 160.
Gottleuba 95.
Gottleuber Grund 96.
Götzinger-Höhle 106. 113. 117 (Abb. 108).
130 (Abb. 118).
Großer Bärenstein 108. 117. 122.
Großer Dom 93. 103. 109. 113. 120 (Abb.
110). 131 (Abb. 119).
Großer Winterberg 74. 115. 128. 130.
Großer Zschand 92. 93. 110.
Großer Zschirnstein 74. 112. 115. 116. 117.

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