Histology of Thyroid follicle

it is the main histological feature of thyroid gland .i hope this ppt help to understand structure and function of thyroid gland.

1. Difference between follicular cells & parafollicular cells

2. Topics Follicular cells Para-follicular cells Secretion T3 and T4 Calcitonin

3. Topics Follicular cells Para-follicular cells Shape and size of cell It is smaller than the parafollicular cell. The shape of the cell vary according to functional state of gland: from simple squamous to low columnar epithelium It is larger than the follicular cell and the shape of the cell is Round

4. Topics Follicular cells Para-follicular cells Staining It takes more staining It takes less staining

5. Topics Follicular cells Para-follicular cells Exposure to luminal surface It is exposed to luminal surface It is never exposed to luminal surface, it is located peripheral part of thyroid follicle

6. Topics Follicular cells Para-follicular cells Nuclei It contains comparatively dark nuclei with two or three prominent nucleoli It contain large pale stain nuclei

7. Topics Follicular cells Para-follicular cells Golgi complex Golgi complex are supranuclear in position Large amount of golgi complex are present but no definite location

8. Topics Follicular cells Para-follicular cells Secretory vesicles Few and Present in apical region It contains numerous secretory vesicle present though out of the cell

9. Topics Follicular cells Para-follicular cells rER Present basally Present in small amount but no definite location

10. Topics Follicular cells Para-follicular cells Lysosome Abundant Present but not abundant

11. Topics Follicular cells Para-follicular cells Endocytotic vesicles or colloidal resorption droplets Present in the apical region of cell No present

12. Topics Follicular cells Para-follicular cells Microvilli Present Absent

13. Topics Follicular cells Para-follicular cells Development Thyroglossal duct 4 th pharyngeal pouch

14. Topics Follicular cells Para-follicular cells Derived from Endoderm Neural crest

15. Identify the cell

16. Follicular cell

17. Identify the cell

18. Shape of cell : round Secretory granules (SG) are numerous Prominent golgi complex (G) Few rER Nuclei contain more euchromatin

19. Shape of cell : round Secretory granules (SG) are numerous Prominent golgi complex (G) Few rER Nuclei contain more euchromatin Para-follicular cell

20. Follicular cell Para-follicular cell

21. Thank you