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IPP chapt-10.pdfsuspension for regular class
IPP chapt-10.pdfsuspension for regular class
yisihakchalachew
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Jun 08, 2024
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About This Presentation
Ipp unit 10
Size:
546.68 KB
Language:
en
Added:
Jun 08, 2024
Slides:
53 pages
Slide Content
Slide 2
Rete Gender
ee dal of depend phase (ictereal phan) range from
Slide 4
i Types Of Emulsions:
Slide 9
Diluted with Diluted with
Water
No Phase Phase Change
| one 7
Diluted with Diluted with
Mater a
— as | >
Phase Change
WO Emulsion WO Emulsion WO Emulsion
OWEmuislon ‘OW Emulsion OW Emulsion
Slide 10
jotivity Test:
3—Bulb does not
[sem
‘Beaker —
Electrodes
OF
Slide 11
Tests Used To identify Emulsion Type:
1 Dye-Solubility Test:
Slide 13
Aqueous Liquid
'Cantinuous Phase) eer
Organic Solvent
(Bropiet Phase)
Slide 14
Mechanism of action of emulsifying
Slide 15
Film of emulsifier
2
2
5
<
Diagrammatic Representation of the Films Formed by the Emulsifying Agent at the
o/w Interface.
Slide 16
ln, hi
Slide 17
Emulsion W/O (Water / Oil) Emulsion O/W (Oil / Water)
Slide 18
emulmiying
A-These trom vegetable sure
1-hater agent may be coqs inte tros groves:
B-Tbsse bem ciel see
Slide 19
2- Finely divided solid:
Slide 20
3- Syniheiis emulsifying agents as
Alkali song:
Slide 22
Gationic surfacionte
5. Cay! timethyiammanium bromide (Ceirinide)
aed bencahonue ehignde
1 Disadvaniagos:
|
Slide 25
Table Ill: HLB Number vs. Solution Function
ME Wterlileruisiers |
Slide 26
; Calculation of HLB:
Srita equation:
Slide 27
On small scale:
Slide 28
Proportions of:
O eee er |
Volatile oil
Slide 29
1 Continental or dry gum method:
|
;
|
Slide 30
ı English or Wet Gum Method
I
y
|
Slide 31
|
|
|
Slide 32
Emulsion Stability:
The instability of pharmaceutical emulsions
may be classified as the following:
Slide 33
Physical Stability Mechanisms
Stable
Emulsion
Zu
Gravitational Coalescence Phase
Separation or Separation
Flocculati
Ti
Ostwald
Ripening
ion
Slide 34
i. Coalescence Se A ii. Flocculation
Y N
ö Good
Emulsion
iii. Creaming iv. Breaking
Slide 35
i nee and creaming:
Slide 36
flats \"
Slide 37
1 Stoke's equation included the factors that
affect the creaming process:
dx/dt = d2 (pi-pe)g/18n
Slide 38
eve velocity upward creaming ]
pipe =+ve [ downward creaming]
pr
prpe = -ve [i
Ona, However tipo is applied.
AV 1 dome
Slide 41
Definition
Reverersability
Agitation
Emulsifying
film around
particles
Internal phase
globules
Effect of phase
volume ratio
Slide 42
li may be brought abect by:
ale ompision formed by salon siceraio ean bo inveried le
we.
Phess ungen con be mama by:
Slide 43
| Graskieg al emulsion aan be due ta:
eg. Monovalcal soup + divalent emp
00. acignia + calins enuisiying agent
Slide 44
ey dal coop: dosemperod by acs
eq. neneveiost compe cated aut by olontralptos much us
Gg. memes emulsifying agonía we nonmpatnie wah
es, aloshal precigtiaies gums and gelaiin
eg aires of u Savon m whieh to we PRESSE eo
aaishic (alaba)
Slide 45
Preservation from microorganisms:
; methyl, propy! and Duty! parabens
exalta
Slide 46
1 on from oxidation:
ı @g-butyiaiod hydrozyanisolo (BHA)
e.g-buiyiaied hydroryioluene (BHT)
Slide 47
1. Determination of particle size and particie
count:
Slide 48
- In case of ofw emulsions
- In use of w/o emulsiones
EAN
Slide 49
e RI ess ns
Slide 50
siabiiiy of emulsions:
1- Aging and iemperaiure
—
- Freezing damage emulsion more than heating ?
Slide 52
Flocculation b
Coalescence
ence a cc
| or liquid crystal
‘Surfactant
aggregates:
oil
Water
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