kustha zinc vs modern supplementses.pptx

pharmacology

1. Kushta Zinc: A Traditional Remedy Hakeem Haseeb Ahmad (Bachelor of Eastern Medicine & Surgery) Healing Herb and Harmony Clinic Modern Zinc Supplements vs

2. CONTENTS Zinc: A Vital Element Across Systems and Traditions Introduction to Kushta Modern Supplements And Pharmalogical Effects Of Zinc (a Comparison between Kushta and Modern Supplements Uses and Scientific Research Final Thoughts And Q&A

3. ALL ABOUT 01 ZINC

4. Zinc: Introduction Zinc is a vital micronutrient essential for immune function, DNA synthesis, and enzymatic processes. While modern medicine relies on synthetic zinc supplements (e.g., gluconate, sulfate) , traditional Unani medicine utilizes  Kushta Zinc — a herbo-mineral formulation prepared through calcination

5. Zinc: A Vital Element Across Systems and Traditions Zinc is essential for immune modulation, wound healing, and antioxidant defense , with a Recommended Dietary Allowance of 8-11 mg/day. Traditional systems emphasize its role in Mizaj and treatment.

6. SOURCES OF ZINC Dietary Sources Meat, shellfish, legumes, and seeds. Traditional Source Kushta Zinc ( e.g.,  Gul-e- Gaozaban ). Modern Supplements Tablets (zinc gluconate), lozenges (acetate), and syrups .

7. INTRODUCTION A TRADITIONAL REMEDY TO KUSHTA

8. Introduction to Kushta In Unani medicine , Kushta refers to calcined metals/minerals detoxified through processes like Taklees (incineration) and Tasfiya (purification). Historically, Kushta formulations were used for enhanced bioavailability and rapid action. For example, Kushta Tutia (zinc calx) treats neurological and skin disorders.

9. KUSTHA ZINC OVERVIEW: Preperation 03 PURIFICATION Raw zinc is purified with herbal decoctions (e.g., Zarnab). 01 TRITURATION Ground with plant extracts to reduce particle size to 1–2 µm (nanoscale) INCINERATION Heated in a Puta system (cow-dung cakes) to form oxide. 02 INGREDIENTS: Zinc oxide combined with Arq-e- Gaozaban (borage distillate) for detoxification.

10. Properties of Kushta Zinc Physicochemical Fine, tasteless powder with high solubility (pH 7–8 in 1% solution). Bioavailability Safety Classical methods (e.g., Gile Hikmat sealing) reduce toxicity; heavy metals within WHO limits. Traditional texts claim rapid absorption due to nano-sizing (validated by modern studies using XRD and SEM).

11. MODERN SUPPLEMENTS & A TRADITIONAL REMEDY Pharmalogical Effects Of Zinc

12. MODERN ZINC SUPPLEMENTS: FORMS 01 04 03 02 Zinc Sulfate 23% elemental zinc; used in lozenges. Zinc Picolinate High bioavailability (research-supported). Zinc Gluconate 14.3% zinc; common in syrups. Dosage Forms Tablets (50 mg), syrups (10 mg/5 mL), and topical creams.

13. MECHANISM OF ACTION MODERN SUPPLEMENTS Absorbed in duodenum via ZIP transporters; efficacy depends on salt form (e.g., Picolinate > gluconate). KUSHTA ZINC Hypothesized to act via: NANOPARTICLES Enhanced mucosal uptake HERB-METAL SYNERGY Plant extracts (e.g., Gaozaban ) may modulate absorption.

14. Pharmacological Effects of Zinc 01 02 05 04 03 MODERN Antioxidant (scavenges ROS), anti-inflammatory (inhibits NF- κB ), and immune-boosting (increases IL-2). SKIN Leucoderma (Baras), wounds TRADITIONAL Kushta Zinc is used for various purposes NEUROLOGY Memory enhancement ( Qoowat -e- Hafiza ) REPRODUCTIVE HEALTH Premature ejaculation.

15. COMPARISON BETWEEN KUSHTA & A TRADITIONAL REMEDY MODERN ZINC SUPPLEMENTS

16. Lorem ipsum dolor sit amet, nibh est. A magna maecenas, quam. ABSORPTION Lorem ipsum dolor sit amet, nibh est. A magna maecenas, quam. FOOD INTERFERENCE Lorem ipsum dolor sit amet, nibh est. A magna maecenas, quam. STUDIES FACTORS KUSHTA ZINC Nano-sized particles (~1 µm) Lorem Ipsum Reduced (herbal matrix) Lorem Ipsum Limited clinical trials Lorem Ipsum MODERN SUPPLEMENTS Salt-dependent (20–40%) Lorem Ipsum Inhibited by phytates Lorem Ipsum Extensive pharmacodynamics data Lorem Ipsum Lorem Ipsum Lorem Ipsum Lorem Ipsum Lorem Ipsum Lorem Ipsum Lorem Ipsum COMPARATIVE BIOAVAILABILITY

17. SCIENTIFIC RESEARCHES & A TRADITIONAL REMEDY USES

18. SCIENTIFIC STUDIES ON KUSHTA ZINC XRD Analysis: Confirms ZnO formation in Kushta Tutia (Rani et al., 2018). FTIR: Detects organic ligands from herbs (e.g., polyphenols).

19. CLINCAL USES OF MODERN ZINC 3 2 1 ACNE Topical zinc reduces inflammation. COLD Lozenges reduce duration by 33%. DIARRHEA WHO recommends 20 mg/day for children.

20. CONCLUSION Kushta Zinc offers a holistic approach with historical efficacy, while modern supplements provide precision. Bridging these through scientific validation can revolutionize zinc therapy .

21. Q&A ANY QUESTIONS OR CONFUSION ?

22. THANK YOU! Hakeem Haseeb Ahmad (Bachelor of Eastern Medicine & Surgery) Healing Herb and Harmony Clinic