mRNA_Vaccines_and_Their_Future_in_Therapeutics.pptx

mRNA vaccines

1. mRNA Vaccines and Their Future in Therapeutics Academic Presentation M.Pharm Level

2. Introduction mRNA vaccines use messenger RNA to instruct cells to produce antigens that trigger an immune response.

3. Mechanism mRNA is delivered via lipid nanoparticles into host cells, where it is translated into antigenic protein, activating immunity.

4. Applications Used in prevention of infectious diseases (COVID-19) and potential in cancer immunotherapy.

5. Advantages Rapid development, no risk of infection, and scalable manufacturing.

6. Limitations Stability issues, cold chain requirements, and short-lived immune response in some cases.

7. Recent Developments mRNA platforms under study for influenza, HIV, and personalized cancer vaccines.

8. Future Prospects Expansion into therapeutic vaccines and autoimmune disease management.

9. Conclusion mRNA vaccines represent a major breakthrough in modern immunization technology.

10. References 1. Pardi N, et al. Nat Rev Drug Discov. 2018;17:261–279. 2. Sahin U, et al. Nature. 2020;585:567–571.