Tips on using my ppt. You can freely download, edit, modify and put your name etc. Don’t be concerned about number of slides. Half the slides are blanks except for the title. First show the blank slides (eg. Aetiology ) > Ask students what they already know about ethology of today's topic. > Then show next slide which enumerates aetiologies. At the end rerun the show – show blank> ask questions > show next slide. This will be an ACTIVE LEARNING SESSION x three revisions. Good for self study also. See notes for bibliography.
Pathophysiology
Pathophysiology Alcoholics, diabetics, and patients who are immunosuppressed are among the most susceptible to splenic abscesses. Preexisting splenic tissue injury and bacteremia
Pathophysiology Hematogenous embolization to a previously normal spleen . Hematogenous spread in the presence of previously altered splenic architecture . splenic infarcts (from trauma) or multiple splenic infarcts (from sickle cell disease or vasculitis . Contiguous spread -pancreatic abscess, gastric or colonic perforations, or subphrenic abscesses
Organisms associated Polymicrobial (up to 50% of cases) Fungi - Candida Unusual flora – Burkholderiapseudomallei Actinomycetes mycobacteria
Symptoms
Symptoms The classical triad of Fever left-upper-quadrant pain Splenomegaly Kehr sign -shoulder pain Pleuritic chest pain General malaise
Signs
Signs Abdominal tenderness Muscle guarding in the left upper quadrant. Edema of the soft tissues overlying the spleen. Costovertebral tenderness. Splenomegaly . Chest findings are nonspecific – dullness at the left lung base left basilar rales elevation of the left hemidiaphragm
Prognosis
Prognosis Bad.
Complications
Complications Life-threatening hemorrhage from the splenic parenchyma or hilar vessels. Pneumothorax Left-side pleural effusion Subphrenic abscess Perforation of the colon, stomach, or small intestine Pancreatic pseudocyst or fistula Postsplenectomy thrombocytosis OPSI
Complications Atelectasis or pneumonia Subphrenic abscess abscesses in the spleen's upper pole can fistulize into the pleura. Abscesses originating from the lower pole can involve the splenic flexure and communicate with the colonic lumen. The stomach and pancreas can be affected
Complications Late iatrogenic complications, such as residual intra-abdominal abscesses, pancreatic or enteric collections. Intestinal obstruction and ventral hernia Recurrent splenic abscess
Radiograph Plain radiographic films of the abdomen and chest- nonspecific Elevated left hemidiaphragm Pleural effusion . abnormal soft-tissue density or a gas collection in the left upper quadrant
Management
Management Empiric broad-spectrum antibiotic therapy later tailored to the culture results Surgical splenectomy laparoscopic splenectomy Percutaneous CT-guided drainage open splenotomy and drain the collection.
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