Systemic Sclerosis presentation for teaching

Short description of key points on Systemic Sclerosis

1. Systemic Sclerosis (Scleroderma) An Interactive Visual Lecture for Medical Students [Your Name] | [Date]

2. Learning Objectives Define systemic sclerosis (SSc) Understand its pathogenesis Recognize clinical features and subtypes Learn diagnostic criteria and investigations Discuss management principles

3. Classification of Systemic Sclerosis Limited cutaneous systemic sclerosis (lcSSc): skin distal to elbows/knees, face; CREST syndrome Diffuse cutaneous systemic sclerosis (dcSSc): skin of trunk and proximal limbs; early organ involvement

4. Pathogenesis Autoimmunity: activation of fibroblasts Vascular damage: endothelial dysfunction Fibrosis: collagen deposition in skin/organs (Visual diagram on next slide)