TERPENOIDS - I D.Pharm ER-20:13T

Unit-IV

1. TERPENOIDS
PRESENTED BY
M.NITHYA., B.PHARM,
LECTURER, ECOP.

2. CONTENT
•Introduction
•Classification of Terpenoids
•Occurrence
•Distribution
•Isolation
•Identification test
•Therapeutic activity
•Pharmaceutical application

3. INTRODUCTION
DEFINITION:
❖Terpenoids are the volatile and aromatic substances
present in plants and giving them their characteristics
fragrance and odour.
❖Terpenoids have been defined as the hydrocarbons of the
plant origin of the general formula (C
5H
8)
n.as well as their
oxygenated, hydrogenated and dehydrogenated
derivatives.

4. CLASSIFICATION OF TERPENOIDS
NAME OF THE CLASS OF
TERPENOIDS
EXAMPLES
Monoterpenes Vetiver, Cumin,Lavander,
Cinnamon,Coriander
Sesquiterpenes Artemisia,Clove,
Diterpenes Taxus
Triterpenes Ambergris
Tetraterpenes Saffron

5. OCCURRENCE
VOLATILEOILS TERPENOIDSPRESENT
CarawayOil Carvone,Limonene
Eucalyptus Oil Cineole
Peppermint Oil Menthol
Fennel Oil Anethol
CloveOil Eugenol
Ginger Oil Zingiberene

6. DISTRIBUTION
❖Widely distributed in certain plant families
E.g., Pinacaae, Lauraceae, Rutaceae, Umbelliferae.
Petals -Rose
Bark and the leaves -Cinnamon
Pericorp –Umbelliferous fruits
Glandular hairs of the stems and leaves –Mints
Flower petals and Rind -Orange

7. ISOLATION OF TERPENOIDS

8. IDENTIFICATION TEST FOR TERPENOIDS
EXPERIMENT OBSERVATION INFERENCE
Salkowskitest:
Extract (5 ml) was mixed
with chloroform (2 ml),
and concentrated
sulphuric acid (3 ml) was
carefully added to form a
layer.
Reddish brown
colouration at the
junction of two
layers
Presence of
Terpenoids

9. Cont.,
EXPERIMENT OBSERVATION INFERENCE
Copperacetate test:
Extract were dissolved in
water and treated with
2-3 drops of copper acetate
solution.
Formation of
Emerald green
colour
Presence of
Terpenoids

10. THERAPEUTIC ACTIVITY OF TERPENOIDS
Sources Medicinal importance
Citrusfruits, Bay leaves,
Eucalyptus, Wild thyme, Lemon
grass.
Analgesic,Anti-Inflammatory,
Antibiotics, Anti-mutagenic
properties.
Balsamicresin, Pine woods and
some citrus fruit.
Anti-Inflammatory, Expectorant,
Bronchodilator and Local
antiseptic.
Thai basil, Clove,Cinnamon leave,
Black Pepper.
Antioxidant, Anti-Inflammatory,
Prevent nephrotoxicity caused by
anti-cancer chemotherapy.
Rose, Lemon. Antibacterial and Antifungal.

11. PHARMACEUTICAL APPLICATION OF
TERPENOIDS
❖Artemisinin –Anti-malarial
❖Glycyrrhizin –Antiulcer, Hepaticidal, Antimicrobial and
Diuretic Properties.
❖Taxol-Anticancer Property.

12. Thank you